Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mihyun Hwang"'
Autor:
Mihyun Hwang, Carine Savarin, Jihye Kim, Jennifer Powers, Natasha Towne, Hyunsuk Oh, Cornelia C. Bergmann
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Triggering receptor expressed on myeloid cells 2 (Trem2) plays a protective role in neurodegenerative diseases. By contrast, Trem2 functions can exacerbate tissue damage during respiratory viral or liver infections. We, therefore,
Externí odkaz:
https://doaj.org/article/fcd86fde0b8444dbb9d773136fefe928
Publikováno v:
Viruses, Vol 15, Iss 12, p 2400 (2023)
Recognition of viruses invading the central nervous system (CNS) by pattern recognition receptors (PRRs) is crucial to elicit early innate responses that stem dissemination. These innate responses comprise both type I interferon (IFN-I)-mediated defe
Externí odkaz:
https://doaj.org/article/02433b735d0d4b28bac3563fc15bf895
Autor:
Eveline Kindler, Cristina Gil-Cruz, Julia Spanier, Yize Li, Jochen Wilhelm, Huib H Rabouw, Roland Züst, Mihyun Hwang, Philip V'kovski, Hanspeter Stalder, Sabrina Marti, Matthias Habjan, Luisa Cervantes-Barragan, Ruth Elliot, Nadja Karl, Christina Gaughan, Frank J M van Kuppeveld, Robert H Silverman, Markus Keller, Burkhard Ludewig, Cornelia C Bergmann, John Ziebuhr, Susan R Weiss, Ulrich Kalinke, Volker Thiel
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006195 (2017)
Coronaviruses are of veterinary and medical importance and include highly pathogenic zoonotic viruses, such as SARS-CoV and MERS-CoV. They are known to efficiently evade early innate immune responses, manifesting in almost negligible expression of ty
Externí odkaz:
https://doaj.org/article/2a3c2f89056640d2ba120a052b6db146
Autor:
Mihyun Hwang, Carine Savarin, Jihye Kim, Jennifer Powers, Natasha Towne, Cornelia C. Bergmann
Background Triggering receptor expressed on myeloid cells 2 (Trem2) plays a protective role in neurodegenerative diseases. By contrast, Trem2 functions can exacerbate tissue damage during respiratory viral or liver infections. We therefore investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327e983fa94494bfadf82c17ec5b5ae9
https://doi.org/10.21203/rs.3.rs-1769173/v1
https://doi.org/10.21203/rs.3.rs-1769173/v1
Autor:
Amy C. Burrows, Patricia Rayman, Ganes C. Sen, Cornelia C. Bergmann, Mihyun Hwang, Soumya Kundu, Nikhil Sharma, Jayasri Das Sarma
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 11, p e1009034 (2020)
PLoS Pathogens, Vol 16, Iss 11, p e1009034 (2020)
The interferon-induced tetratricopeptide repeat protein (Ifit2) protects mice from lethal neurotropic viruses. Neurotropic coronavirus MHV-RSA59 infection of Ifit2-/- mice caused pronounced morbidity and mortality accompanied by rampant virus replica
Autor:
Cornelia C. Bergmann, Mihyun Hwang
Publikováno v:
Viral Immunology
A variety of viruses can induce central nervous system (CNS) infections and neurological diseases, although the incidence is rare. Similar to peripheral infections, IFNα/β induction and signaling constitutes a first line of defense to limit virus d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568074124547a0ea149192648f55368d
https://europepmc.org/articles/PMC6350053/
https://europepmc.org/articles/PMC6350053/
Publikováno v:
Journal of Virology
The prevalence and role of antigen-specific Bmem in the CNS during viral encephalomyelitis is largely undefined. A lack of reliable markers identifying murine Bmem has made it difficult to assess their contribution to local antiviral protection via a
Autor:
David R. Hinton, Mihyun Hwang, Cornelia C. Bergmann, Stephen A. Stohlman, Booki Min, Timothy W. Phares
Publikováno v:
Immunology
CD4 T-cell help is not a universal requirement for effective primary CD8 T cells but is essential to generate memory CD8 T cells capable of recall responses. This study examined how CD4 T cells affect primary and secondary anti-viral CD8 T-cell respo
Autor:
Mihyun Hwang1, Bergmann, Cornelia C.1 bergmac@ccf.org
Publikováno v:
Journal of Virology. Oct2020, Vol. 94 Issue 20, p1-20. 20p.
Autor:
Nadja Karl, Hanspeter Stalder, Mihyun Hwang, Luisa Cervantes-Barragan, Yize Li, Volker Thiel, Sabrina Marti, Philip V'kovski, Julia Spanier, Christina Gaughan, Markus Keller, Susan R. Weiss, Cornelia C. Bergmann, Robert H. Silverman, Cristina Gil-Cruz, Jochen Wilhelm, Matthias Habjan, Ulrich Kalinke, Frank J. M. van Kuppeveld, Burkhard Ludewig, Roland Züst, Huib H. Rabouw, Eveline Kindler, Ruth Elliot, John Ziebuhr
Publikováno v:
PLOS Pathogens
Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195
PLoS Pathogens, 13(2). Public Library of Science
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 2, p e1006195 (2017)
Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195
PLoS Pathogens, 13(2). Public Library of Science
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 2, p e1006195 (2017)
Coronaviruses are of veterinary and medical importance and include highly pathogenic zoonotic viruses, such as SARS-CoV and MERS-CoV. They are known to efficiently evade early innate immune responses, manifesting in almost negligible expression of ty