Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mihovil Pletikos"'
Autor:
Marco Onorati, Zhen Li, Fuchen Liu, André M.M. Sousa, Naoki Nakagawa, Mingfeng Li, Maria Teresa Dell’Anno, Forrest O. Gulden, Sirisha Pochareddy, Andrew T.N. Tebbenkamp, Wenqi Han, Mihovil Pletikos, Tianliuyun Gao, Ying Zhu, Candace Bichsel, Luis Varela, Klara Szigeti-Buck, Steven Lisgo, Yalan Zhang, Anze Testen, Xiao-Bing Gao, Jernej Mlakar, Mara Popovic, Marie Flamand, Stephen M. Strittmatter, Leonard K. Kaczmarek, E.S. Anton, Tamas L. Horvath, Brett D. Lindenbach, Nenad Sestan
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2576-2592 (2016)
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation and characterization, including single-cell RNA-seq, of neocortical and spinal cord neuroep
Externí odkaz:
https://doaj.org/article/7ed0523b8c024cdea2dcfa2c3cd7c835
Autor:
Yury M. Morozov, Zhen W. Zhuang, Stefano G. Daniele, Mihovil Pletikos, Mario Skarica, Stephen G. Waxman, Rafeed Alkawadri, Navjot Kaur, John Silbereis, Francesca Talpo, Nenad Sestan, Brian S. Tanaka, Zvonimir Vrselja, Stephen R. Latham, André M. M. Sousa, Zhao Liu, Albert J. Sinusas
Publikováno v:
Nature. 568:336-343
The brains of humans and other mammals are highly vulnerable to interruptions in blood flow and decreases in oxygen levels. Here we describe the restoration and maintenance of microcirculation and molecular and cellular functions of the intact pig br
Autor:
Ed S. Lein, Yuka Imamura Kawasawa, Mingfeng Li, Melissa K. Edler, James P. Noonan, Mario Skarica, Marta Melé, Raquel Garcia Perez, Nenad Sestan, Joel E. Kleinman, Mihovil Pletikos, Patrick R. Hof, Kyle A. Meyer, Bernardo Stutz, Forrest O. Gulden, Alexa R. Stephenson, John D. Elsworth, Mary Ann Raghanti, Thomas M. Hyde, Daniel R. Weinberger, Mark Gerstein, Matthew W. State, Akemi Shibata, John J. Ely, Ying Zhu, Tiago Carvalho, Marco Onorati, Chet C. Sherwood, Richard P. Lifton, André M. M. Sousa, Mark Reimers, Fuchen Liu, Shrikant Mane, Tamas L. Horvath, Robert R. Kitchen, Tomas Marques-Bonet, James A. Knowles, Andrew T.N. Tebbenkamp
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat. Dipósit de la Recerca de Catalunya
To better understand the molecular and cellular differences in brain organization between human and nonhuman primates, we performed transcriptome sequencing of 16 regions of adult human, chimpanzee, and macaque brains. Integration with human single-c
Autor:
Jean Kanyo, Angus C. Nairn, Edward Z. Voss, Becky C. Carlyle, André M. M. Sousa, Mihovil Pletikos, Nenad Sestan, TuKiet T. Lam, Robert R. Kitchen, Mark Gerstein
Publikováno v:
Nature neuroscience
Detailed observations of transcriptional, translational and post-translational events in the human brain are essential to improving our understanding of its development, function and vulnerability to disease. Here, we exploited label-free quantitativ
Autor:
Virendra Mishra, Susumu Mori, Qinmu Peng, Qiaowen Yu, Lei Feng, Nenad Sestan, Hao Huang, Mihovil Pletikos, Shuwei Liu, Tina Jeon, Steven S. Hsiao, Minhui Ouyang, Michael I. Miller
Publikováno v:
Brain Structure and Function. 222:4131-4147
Animal models of the rhesus macaque (Macaca mulatta), the most widely used nonhuman primate, have been irreplaceable in neurobiological studies. However, a population-averaged macaque brain diffusion tensor imaging (DTI) atlas, including comprehensiv
Autor:
James T.R. Walters, Ed S. Lein, Donna M. Werling, Paola Giusti-Rodríguez, Mark Gerstein, Shuang Liu, Mihovil Pletikos, Patrick F. Sullivan, Susan M. Sunkin, Fulai Jin, Daniel R. Weinberger, Yuka Imamura Kawasawa, Daifeng Wang, Ming Hu, Michael Conlon O'Donovan, Mingfeng Li, Matthew W. State, Stephen Sanders, Hyo Jung Kang, Jinmyung Choi, Daniel H. Geschwind, Thomas M. Hyde, Michael Hawrylycz, Mark Reimers, Yurae Shin, James A. Knowles, Sirisha Pochareddy, Pat Levitt, Christiaan de Leeuw, Nenad Sestan, Gabriel Santpere, André M. M. Sousa, Danielle Posthuma, Sydney Muchnik, Ying Zhu, Michael John Owen, Oleg V. Evgrafov, Hyejung Won, PsychENCODE Developmental Subgroup, Xuming Xu, Forrest O. Gulden, Zhen Li, Yun Li, Robert R. Kitchen, Antonio F. Pardiñas, Joel E. Kleinman, Belen Lorente-Galdos
Publikováno v:
Science (New York, N.Y.), vol 362, iss 6420
Science, 362(6420):1264, 1-15. American Association for the Advancement of Science
Li, M, Santpere, G, Kawasawa, Y I, Evgrafov, O V, Gulden, F O, Pochareddy, S, Sunkin, S M, Li, Z, Shin, Y, Zhu, Y, Sousa, A M M, Werling, D M, Kitchen, R R, Kang, H J, Pletikos, M, Choi, J, Muchnik, S, Xu, X, Wang, D, Lorente-Galdos, B, Liu, S, Giusti-Rodríguez, P, Won, H, De Leeuw, C A, Pardiñas, A F, Hu, M, Jin, F, Li, Y, Owen, M J, O'Donovan, M C, Walters, J T R, Posthuma, D, Levitt, P, Weinberger, D R, Hyde, T M, Kleinman, J E, Geschwind, D H, Hawrylycz, M J, State, M W, Sanders, S J, Sullivan, P F, Gerstein, M B, Lein, E S, Knowles, J A & Sestan, N 2018, ' Integrative functional genomic analysis of human brain development and neuropsychiatric risks ', Science, vol. 362, no. 6420, 1264, pp. 1-15 . https://doi.org/10.1126/science.aat7615
Science, 362(6420):1264, 1-15. American Association for the Advancement of Science
Li, M, Santpere, G, Kawasawa, Y I, Evgrafov, O V, Gulden, F O, Pochareddy, S, Sunkin, S M, Li, Z, Shin, Y, Zhu, Y, Sousa, A M M, Werling, D M, Kitchen, R R, Kang, H J, Pletikos, M, Choi, J, Muchnik, S, Xu, X, Wang, D, Lorente-Galdos, B, Liu, S, Giusti-Rodríguez, P, Won, H, De Leeuw, C A, Pardiñas, A F, Hu, M, Jin, F, Li, Y, Owen, M J, O'Donovan, M C, Walters, J T R, Posthuma, D, Levitt, P, Weinberger, D R, Hyde, T M, Kleinman, J E, Geschwind, D H, Hawrylycz, M J, State, M W, Sanders, S J, Sullivan, P F, Gerstein, M B, Lein, E S, Knowles, J A & Sestan, N 2018, ' Integrative functional genomic analysis of human brain development and neuropsychiatric risks ', Science, vol. 362, no. 6420, 1264, pp. 1-15 . https://doi.org/10.1126/science.aat7615
INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes us uniquely human. The development of the brain is a highly complex process, and this process is reliant on precise regulation of molecular and cellular events grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d2f55db6e1ad43aca6bf9fa87db245
https://escholarship.org/uc/item/2gt1b22t
https://escholarship.org/uc/item/2gt1b22t
Autor:
Zvonimir, Vrselja, Stefano G, Daniele, John, Silbereis, Francesca, Talpo, Yury M, Morozov, André M M, Sousa, Brian S, Tanaka, Mario, Skarica, Mihovil, Pletikos, Navjot, Kaur, Zhen W, Zhuang, Zhao, Liu, Rafeed, Alkawadri, Albert J, Sinusas, Stephen R, Latham, Stephen G, Waxman, Nenad, Sestan
Publikováno v:
Nature. 568(7752)
The brains of humans and other mammals are highly vulnerable to interruptions in blood flow and decreases in oxygen levels. Here we describe the restoration and maintenance of microcirculation and molecular and cellular functions of the intact pig br
Autor:
Daniel Franjic, Flora M. Vaccarino, Mihovil Pletikos, Bo Zhou, Jessica Mariani, Bo Juen Chen, Elisa Venturini, Alexej Abyzov, Alexander E. Urban, Reenal Pattni, Nenad Sestan, Tanmoy Roychowdhury, Taejeong Bae, Bridget Riley-Gillis, Livia Tomasini
Publikováno v:
Science (New York, N.Y.). 359(6375)
Brain mutations, young and old Most neurons that make up the human brain are postmitotic, living and functioning for a very long time without renewal (see the Perspective by Lee). Bae et al. examined the genomes of single neurons from the prenatal de
Autor:
Amy F.T. Arnsten, Peter Davies, Kelly A. Bordner, Arthur A. Simen, Mihovil Pletikos, Becky C. Carlyle, Nenad Sestan, Lu E. Jin, George E. Craft, Min Wang, Constantinos D. Paspalas, Angus C. Nairn, Yang Yang, Brian P. Ramos
Publikováno v:
Proceedings of the National Academy of Sciences. 111:5036-5041
The pattern of neurodegeneration in Alzheimer's disease (AD) is very distinctive: neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau selectively affect pyramidal neurons of the aging association cortex that interconnect extensively th
Autor:
Yuka Imamura Kawasawa, Mingfeng Li, Kyle A. Meyer, Mihovil Pletikos, Ying Zhu, Feng Cheng, Nenad Sestan, André M. M. Sousa, Goran Sedmak
Publikováno v:
Neuron. 81:321-332
SummaryTranscriptional events involved in the development of human cerebral neocortex are poorly understood. Here, we analyzed the temporal dynamics and laterality of gene expression in human and macaque monkey neocortex. We found that interareal dif