Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mihoka Kojima"'
Autor:
Takayuki Matsumoto, Tomoki Katome, Tsuneo Kobayashi, Keisuke Takayanagi, Mihoka Kojima, Kumiko Taguchi
Publikováno v:
Pharmacology. 106:435-445
Introduction: Femoral arterial dysfunction including abnormal vascular responsiveness to endogenous ligands was often seen in arterial hypertension. Extracellular nucleotides including uridine 5′-diphosphate (UDP) and uridine 5′-triphosphate (UTP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e12442a5be48bd6d33fd176fbecaaa
https://doi.org/10.1159/000516893
https://doi.org/10.1159/000516893
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1987-1992
Extracellular nucleotides play an important role in the regulation of vascular function, and an abnormal vascular function is an important participant in the development and progression of diabetic vascular complications. The purpose of this study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a097bda9709cfe8de54966075902c3
https://doi.org/10.1248/bpb.b20-00653
https://doi.org/10.1248/bpb.b20-00653
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:569-573
Although substantial evidence suggests that an increase in the level of trimethylamine-N-oxide (TMAO) is associated with the risk of cardiovascular diseases, including atherosclerosis, chronic kidney diseases, and hypertension, the direct effect of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b5c97992a17517c47aee1770cd644c
https://doi.org/10.1248/bpb.b19-00957
https://doi.org/10.1248/bpb.b19-00957
Publikováno v:
American Journal of Hypertension
Gut microbiota have been emerging as important contributors to the regulation of host homeostasis. Accordingly, several substances converted by gut microbiota can have beneficial or adverse effects on human health. Among them, S-equol, which is produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfa27b4ab6f8eb423f882d3b374c1d5
http://europepmc.org/articles/PMC7481967
http://europepmc.org/articles/PMC7481967
Publikováno v:
Cell and tissue research. 390(2)
Matrix metalloproteinases (MMPs) and tumor necrosis factor (TNF)-α contribute to the pathogenesis of several ocular diseases. Previous studies have shown that MMP-9 activation plays an important role in capillary degeneration in injured retinas. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa44171052414e43adbc9136d483771c
https://pubmed.ncbi.nlm.nih.gov/35895162
https://pubmed.ncbi.nlm.nih.gov/35895162
Autor:
Tsuneo Kobayashi, Kumiko Taguchi, Tomoki Katome, Mihoka Kojima, Keisuke Takayanagi, Takayuki Matsumoto
Publikováno v:
Biologicalpharmaceutical bulletin. 44(10)
We investigated the vascular response to nucleobase adenine using freshly isolated superior mesenteric arteries of spontaneously hypertensive rats (SHR) and its control, Wistar Kyoto (WKY) rats. Endothelium-dependent and endothelium-independent relax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0738a20ae31d662a9cb5eae59072d73
https://pubmed.ncbi.nlm.nih.gov/34602562
https://pubmed.ncbi.nlm.nih.gov/34602562
Autor:
Mihoka Kojima, Kumiko Taguchi, Keisuke Takayanagi, Shota Kobayashi, Takayuki Matsumoto, Tsuneo Kobayashi
Publikováno v:
Biological and Pharmaceutical Bulletin. 42:1048-1053
Previous research has indicated that high insulin affects vascular function. Equol is an active metabolite of daidzein, an isoflavone produced from soy by intestinal microbial flora, with beneficial effects on the vascular system. This study investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d861447273729e68d3d46ba8978bf1f
https://doi.org/10.1248/bpb.b19-00051
https://doi.org/10.1248/bpb.b19-00051
Publikováno v:
Biologicalpharmaceutical bulletin. 43(8)
Although vascular dysfunction is a key event in the development of diabetic complications, and abnormal toll-like receptor 4 (TLR4) may contribute to the pathophysiology of vascular diseases, the direct relationships between TLR4 and vascular functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c5c71460fd6e3f26230a7372fd1acf
https://pubmed.ncbi.nlm.nih.gov/32741952
https://pubmed.ncbi.nlm.nih.gov/32741952
Autor:
Mihoka Kojima, Keisuke Takayanagi, Tomoki Katome, Takayuki Matsumoto, Tsuneo Kobayashi, Kumiko Taguchi
Publikováno v:
Purinergic Signal
Uridine 5′-triphosphate (UTP) has an important role as an extracellular signaling molecule that regulates inflammation, angiogenesis, and vascular tone. While chronic hypertension has been shown to promote alterations in arterial vascular tone regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7007a094dc0f6ff5e8bebc96b485b0f1
https://pubmed.ncbi.nlm.nih.gov/32862324
https://pubmed.ncbi.nlm.nih.gov/32862324
Publikováno v:
Biologicalpharmaceutical bulletin. 43(3)
Although substantial evidence suggests that an increase in the level of trimethylamine-N-oxide (TMAO) is associated with the risk of cardiovascular diseases, including atherosclerosis, chronic kidney diseases, and hypertension, the direct effect of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29ef0d2d389edd440647aa39880f2327
https://pubmed.ncbi.nlm.nih.gov/32115516
https://pubmed.ncbi.nlm.nih.gov/32115516