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Akademický článek

CAMK2D: a novel molecular target for BAP1-deficient malignant mesothelioma

Autor: Sivasundaram Karnan, Akinobu Ota, Hideki Murakami, Md. Lutfur Rahman, Md Wahiduzzaman, Muhammad Nazmul Hasan, Lam Quang Vu, Ichiro Hanamura, Akihito Inoko, Miho Riku, Hideaki Ito, Yoshifumi Kaneko, Toshinori Hyodo, Hiroyuki Konishi, Shinobu Tsuzuki, Yoshitaka Hosokawa

Publikováno v: Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)

Abstract Malignant mesothelioma (MMe) is a rare but aggressive malignancy. Although the molecular genetics of MMe is known, including BRCA1-associated protein-1 (BAP1) gene alterations, the prognosis of MMe patients remains poor. Here, we generated B

Externí odkaz: https://doaj.org/article/ec1ed1cefb4f43d0a333234d3c0668cd

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Akademický článek

Expression and Prognostic Significance of CD47–SIRPA Macrophage Checkpoint Molecules in Colorectal Cancer

Autor: Akane Sugimura-Nagata, Akira Koshino, Satoshi Inoue, Aya Matsuo-Nagano, Masayuki Komura, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Toyonori Tsuzuki, Satoru Takahashi, Kunio Kasugai, Kenji Kasai, Shingo Inaguma

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 5, p 2690 (2021)

Despite the confirmed anti-cancer effects of T-cell immune checkpoint inhibitors, in colorectal cancer (CRC) they are only effective in a small subset of patients with microsatellite-unstable tumors. Thus, therapeutics targeting other types of CRCs o

Externí odkaz: https://doaj.org/article/813367c0850e497a925e7928b0f30c15

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