Výsledky vyhledávání - "Miho Murachi"

Drug design and synthesis of ε opioid receptor agonist: 17-(cyclopropylmethyl)-4,5α-epoxy-3,6β-dihydroxy-6,14-endoethenomorphinan-7α-(N-methyl-N-phenethyl)carboxamide (TAN-821) inducing antinociception mediated by putative ε opioid receptor

Autor: Miho Murachi, Koji Kawai, Toshiaki Tanaka, Minoru Narita, Hirokazu Mizoguchi, Leon F. Tseng, Hideaki Fujii, Hiroshi Nagase

Publikováno v: Bioorganic & Medicinal Chemistry. 12:4133-4145

Here we report the new drug design and synthesis of a series of 6,14-endoethenomorphinan-7-carboxamide derivatives as a putative epsilon opioid receptor agonist. One of these compounds, 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,6beta-dihydroxy-6,14-end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d196434b4c550f64202ca8dc1766dadd
https://doi.org/10.1016/j.bmc.2004.05.024

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SUPPRESSION OF ALLOGRAFT RESPONSES INDUCED BY INTERLEUKIN-6, WHICH SELECTIVELY MODULATES INTERFERON-?? BUT NOT INTERLEUKIN-2 PRODUCTION1

Autor: Hiromi Fujiwara, Xu-Guang Tai, Miho Murachi, Michio Tomura, Izumi Nakatani, Kazuhito Toyo-oka

Publikováno v: Transplantation. 64:757-763

BACKGROUND Interferon (IFN)-gamma produced by activated T cells represents an important effector cytokine in mediating an inflammatory response. METHODS The present study investigated the modulation of allograft responses by inhibiting IFN-gamma prod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa07debf5476b78189bfbce7ba6ae812
https://doi.org/10.1097/00007890-199709150-00017

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