Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Miho Kasama"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 273:H1800-H1806
To investigate the selective parasympathetic control of atrioventricular (AV) conduction during sympathetic activation, we studied the effects of cervical vagus nerve stimulation on the positive dromotropic responses to sympathetic interventions befo
Autor:
Yuji Hoyano, Yasuyuki Furukawa, Miho Kasama, Hirofumi Nakano, Shigetoshi Chiba, Hiroshi Imamura, Kyohei Yamazaki
Publikováno v:
Journal of Cardiovascular Pharmacology. 28:507-512
To investigate the role of delayed rectifier potassium current (I K ) on the sympathetic control of the heart, we studied the effects of E-403 1, a blocker of the rapidly activating type of I K (I Kr ), on the chronotropic, dromotropic, and inotropic
Autor:
Yuji Hoyano, Shigetoshi Chiba, Hirosi Imamura, Miho Kasama, Takanori Yonezawa, Yasuyuki Furukawa
Publikováno v:
European Journal of Pharmacology. 309:51-58
We investigated the effects of a novel bradycardic agent, bertosamil (3-isobutyl-7-isopropyl-9,9-pentamethylene-3,7-diazabicyclo[3.3.1]nonane sesquihydrogenfumarate), on the sinus rate and atrial contractile force and the left ventricular contractile
Autor:
Hirofumi Nakano, Shigetoshi Chiba, Hiroshi Imamura, Miho Kasama, Yasuyuki Furukawa, Kyouhei Yamazaki
Publikováno v:
Journal of Cardiovascular Pharmacology. 26:957-964
To investigate the role of the hyperpolarization-activated current (If) on the subsidiary pacemaker activity of the heart, we studied the effects of an I f inhibitor, zatebradine, and a L-type Ca channel inhibitor, verapamil, on the atrioventicular (
Autor:
Osamu, Akasaka, Shigeru, Iwase, Haruo, Miwa, Tomoko, Ando, Seie, Morita, Ryonho, Koh, Miho, Kasama, Rie, Matsueda, Hideaki, Anan
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 36(11)
We performed combination chemotherapy using S-1 and CPT-11 for advanced and recurrent stomach carcinoma in order to study the clinical efficacy thereof. The subjects comprised 13 patients aged 55 to 78 with a PS of 0 to 2, who had histologically conf
Publikováno v:
Masui. The Japanese journal of anesthesiology. 58(10)
We report the case of a 37-year-old woman who developed severe pain in bilateral legs and hip in the eighth month of pregnancy. She was diagnosed as transient osteoporosis of the hip in pregnancy by the MRI findings. NSAID is contraindicated for late
Publikováno v:
Japanese journal of pharmacology. 78(4)
We investigated the effects of hypothermia (25 degrees C) on the chronotropic and inotropic effects of zatebradine (a blocker of hyperpolarization-activated inward current, I(f)), E-4031 (a blocker of the rapid type of the delayed rectifier K+ curren
Autor:
Yasuyuki Furukawa, Hiroshi Imamura, Takanori Yonezawa, Yuji Hoyano, Miho Kasama, Shigetoshi Chiba
Publikováno v:
Japanese journal of pharmacology. 76(1)
Vagal activation influences various cardiac functions as well as occurrence of arrhythmias. Inhibition of a rapid type of delayed rectifier K+ current (I[Kr]) has been reported to be effective for the treatment of both ventricular and supraventricula
Publikováno v:
European journal of pharmacology. 297(3)
To investigate the effect of the delayed rectifier K+ current (IK) on the atrioventricular (AV) node of the heart in situ, we studied the direct effects of (1-[2-(6-methyl-2-pyridyl)ethyl]-4-(methylsulfonyl-aminobenzoyl)piperidi ne (E-4031), an IKr (
Autor:
Yasuyuki Furukawa, Hiroshi Imamura, Miho Kasama, Yuji Hoyano, Shigetoshi Chiba, Takeshi Oguchi
Publikováno v:
Journal of cardiovascular pharmacology. 27(1)
The clinical use of doxorubicin, an anthracycline antineoplastic agent, is limited by its cardiotoxicity. Although several previous reports have shown neurotoxic effects of doxorubicin, there is little information about the acute effects of doxorubic