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pro vyhledávání: '"Miho Ikenaga"'
A Novel CYP11B2-Specific Imaging Agent for Detection of Unilateral Subtypes of Primary Aldosteronism
Autor:
William F. Young, Yoshihiro Doi, Hideo Saji, Abe Tsutomu, Izawa Akihiro, Miho Ikenaga, Kei Akama, Hiroki Matsumoto, Hiroyuki Kimura, Yuki Okumura, Mitsuhide Naruse, Kuniaki Mukai, Nobuya Kobashi
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:1008-1015
Although adrenal vein sampling is the standard method to distinguish unilateral from bilateral forms of primary aldosteronism, it is an invasive and technically difficult procedure. (11)C-metomidate (MTO)-positron emission tomography was reported as
Publikováno v:
Molecular Pharmaceutics. 11:568-579
In recent years, it has become increasingly important to test the safety of circulating metabolites of novel drugs as part of drug discovery and development programs. Accordingly, it is essential to develop suitable methods for identifying the major
Publikováno v:
Toxicology and Applied Pharmacology. 263:244-250
We previously reported a quantitative time-lapse imaging (QTLI)-based analysis method to assess drug-drug interactions (DDI) at multidrug resistance-associated protein 2 (Mrp2) in rat sandwich-cultured hepatocyte (SCH) system, utilizing the fluoresce