Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Mihir Shetty"'
Autor:
Valentino Clemente, Asumi Hoshino, Joyce Meints, Mihir Shetty, Tim Starr, Michael Lee, Martina Bazzaro
Publikováno v:
Cells, Vol 10, Iss 7, p 1604 (2021)
UNC-45A (Protein unc-45 homolog A) is a cytoskeletal-associated protein with a dual and non-mutually exclusive role as a regulator of the actomyosin system and a Microtubule (MT)-destabilizing protein, which is overexpressed in human cancers includin
Externí odkaz:
https://doaj.org/article/f7f826690f354d06914917f04238e658
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4750 (2021)
Ovarian clear cell carcinoma (OCCC) is a rare but chemorefractory tumor. About 50% of all OCCC patients have inactivating mutations of ARID1A, a member of the SWI/SNF chromatin-remodeling complex. Members of the SWI/SNF remodeling have emerged as reg
Externí odkaz:
https://doaj.org/article/a93338dc0ea148118f7f8dce904a5726
Autor:
Michelle A. Glasgow, Peter Argenta, Juan E. Abrahante, Mihir Shetty, Shobhana Talukdar, Paula A. Croonquist, Mahmoud A. Khalifa, Timothy K. Starr
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2131 (2019)
The majority of patients with high-grade serous ovarian cancer (HGSOC) initially respond to chemotherapy; however, most will develop chemotherapy resistance. Gene signatures may change with the development of chemotherapy resistance in this populatio
Externí odkaz:
https://doaj.org/article/5d3deef6ec424645b88890fb7176e576
Autor:
Travis J Gates, Ce Yuan, Mihir Shetty, Thomas Kaiser, Andrew C Nelson, Aastha Chauhan, Timothy K Starr, Christopher Staley, Subbaya Subramanian
Publikováno v:
Cancers; Volume 15; Issue 8; Pages: 2260
Chronic inflammation of the colon (colitis) is a known risk factor for inflammatory-driven colorectal cancers (idCRC), and intestinal microbiota has been implicated in the etiology of id-CRC. Manipulation of the microbiome is a clinically viable ther
Autor:
Martina Bazzaro, Emil Lou, S. John Weroha, Mahmoud Khalifa, Nathan Rubin, Ruth Baker, Britt K. Erickson, Andrew Nelson, Mihir Shetty, Asumi Hoshino, Valentino Clemente
Targeting glutamine metabolism has emerged as a novel therapeutic strategy for several human cancers, including ovarian cancer. The primary target of this approach is the kidney isoform of glutaminase, glutaminase 1 (GLS1), a key enzyme in glutamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c1766da97b78ba4471e9bc1cc33067
https://doi.org/10.1158/2767-9764.c.6550917.v1
https://doi.org/10.1158/2767-9764.c.6550917.v1
Autor:
Martina Bazzaro, Emil Lou, S. John Weroha, Mahmoud Khalifa, Nathan Rubin, Ruth Baker, Britt K. Erickson, Andrew Nelson, Mihir Shetty, Asumi Hoshino, Valentino Clemente
Figure S1, Table S1, Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69768684865b977d2afaa5cbc88abfb7
https://doi.org/10.1158/2767-9764.22545360.v1
https://doi.org/10.1158/2767-9764.22545360.v1
Autor:
Martina Bazzaro, Melissa Gardner, Michael K. Lee, Joyce Meints, Teng Ai, Liqiang Chen, Mihir Shetty, Edith Emmings, Vijayalakshmi Shridhar, Mark McClellan, Courtney Coombes, Qing Yang, Yoshie Iizuka, Ashley Mooneyham
UNC-45A, a highly conserved member of the UCS (UNC45A/CRO1/SHE4P) protein family of cochaperones, plays an important role in regulating cytoskeletal-associated functions in invertebrates and mammalian cells, including cytokinesis, exocytosis, cell mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e73f2e83f4f2df708b1ac8317f54bcac
https://doi.org/10.1158/1541-7786.c.6541335
https://doi.org/10.1158/1541-7786.c.6541335
Autor:
Martina Bazzaro, Melissa Gardner, Michael K. Lee, Joyce Meints, Teng Ai, Liqiang Chen, Mihir Shetty, Edith Emmings, Vijayalakshmi Shridhar, Mark McClellan, Courtney Coombes, Qing Yang, Yoshie Iizuka, Ashley Mooneyham
Linear range for quantitative Western blot analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04adec59f54a3333e0eaf7d1e069c98d
https://doi.org/10.1158/1541-7786.22516284.v1
https://doi.org/10.1158/1541-7786.22516284.v1
Autor:
Martina Bazzaro, Melissa Gardner, Michael K. Lee, Joyce Meints, Teng Ai, Liqiang Chen, Mihir Shetty, Edith Emmings, Vijayalakshmi Shridhar, Mark McClellan, Courtney Coombes, Qing Yang, Yoshie Iizuka, Ashley Mooneyham
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99dc629960d3799e5b2d742b6cae8241
https://doi.org/10.1158/1541-7786.22516278.v1
https://doi.org/10.1158/1541-7786.22516278.v1
Autor:
Levi Waldron, Timothy K. Starr, Markus Riester, Li-Xuan Qin, Michael J. Birrer, Giovanni Parmigiani, Martin Morgan, Sally A. Mullany, Mihir Shetty, Shobhana Talukdar, Zenas Chang, Boris J. Winterhoff, Andrew C. Nelson, Claire Daughters, Sarah A. Munro, Christine M. Henzler, Rebecca S. LaRue, Lucas Schiffer, Marcel Ramos, Sehyun Oh, Ludwig Geistlinger
Multiple studies have identified transcriptome subtypes of high-grade serous ovarian carcinoma (HGSOC), but their interpretation and translation are complicated by tumor evolution and polyclonality accompanied by extensive accumulation of somatic abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c8ca21f7d271d0a414efc6e902b882
https://doi.org/10.1158/0008-5472.c.6512406.v1
https://doi.org/10.1158/0008-5472.c.6512406.v1