Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Mihir Parikh"'
Autor:
Mihir Parikh, Broderick C. Hirst, Kimberley A. O’Hara, Thane G. Maddaford, J. Alejandro Austria, Aleksandra Stamenkovic, Liping Yu, Branislav Kura, Bhavana Garg, Thomas Netticadan, Spencer D. Proctor, Grant N. Pierce
Publikováno v:
Nutrients, Vol 16, Iss 4, p 466 (2024)
Non-alcoholic fatty liver disease (NAFLD), a significant cause of chronic liver disease, presents a considerable public health concern. Despite this, there is currently no treatment available. This study aimed to investigate dietary flaxseed in the J
Externí odkaz:
https://doaj.org/article/2bdf158fee2f4593926b9e4ebbda766b
Publikováno v:
Heliyon, Vol 6, Iss 4, Pp e03803- (2020)
Doxorubicin (DOXO), a potent and widely used chemotherapeutic agent, causes irreversible heart failure by increasing oxidative stress, which limits its clinical utility. Nuclear factor erythroid-derived 2 -like 2 (Nrf2) is a prominent central regulat
Externí odkaz:
https://doaj.org/article/e2f92b1babf14a0e843187a24942a623
Autor:
Mihir Parikh, Saumya Shah, Ratnadeep Basu, Konrad S. Famulski, Daniel Kim, John C. Mullen, Philip F. Halloran, Gavin Y. Oudit
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2050 (2022)
Left ventricular assist device (LVAD) use in patients with dilated cardiomyopathy (DCM) can lead to a differential response in the LV and right ventricle (RV), and RV failure remains the most common complication post-LVAD insertion. We assessed trans
Externí odkaz:
https://doaj.org/article/e15d419bba0043c1b01e067e3e01b41f
Autor:
Pema Raj, Karen Sayfee, Mihir Parikh, Liping Yu, Jeffrey Wigle, Thomas Netticadan, Shelley Zieroth
Publikováno v:
Molecules, Vol 26, Iss 16, p 5006 (2021)
The development and progression of heart failure (HF) due to myocardial infarction (MI) is a major concern even with current optimal therapy. Resveratrol is a plant polyphenol with cardioprotective properties. Sacubitril/valsartan is known to be bene
Externí odkaz:
https://doaj.org/article/039ea422933a4235914cabaf62af130a
Autor:
Mihir Parikh, Grant N. Pierce
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4995 (2021)
Despite advances in diagnostic, prognostic, and treatment modalities, myocardial infarction (MI) remains a leading cause of morbidity and mortality. Impaired cellular signaling after an MI causes maladaptive changes resulting in cardiac remodeling. M
Externí odkaz:
https://doaj.org/article/2ab0b8aabdb54233a6b6191a35ef16b7
Autor:
Craig Resch, Mihir Parikh, J. Alejandro Austria, Spencer D. Proctor, Thomas Netticadan, Heather Blewett, Grant N. Pierce
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 1037 (2021)
There is an increased interest in the gut microbiota as it relates to health and obesity. The impact of diet and sex on the gut microbiota in conjunction with obesity also demands extensive systemic investigation. Thus, the influence of sex, diet, an
Externí odkaz:
https://doaj.org/article/ce1235d555334190bb9b0552c6871a8d
Autor:
Mihir Parikh, Branislav Kura, Kimberley A. O’Hara, Elena Dibrov, Thomas Netticadan, Jan Slezak, Grant N. Pierce
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1297 (2020)
MicroRNAs (miRNAs/miRs) such as miR-1, miR-133a, miR-133b, miR-135a, and miR-29b play a key role in many cardiac pathological remodeling processes, including apoptosis, fibrosis, and arrhythmias, after a myocardial infarction (MI). Dietary flaxseed h
Externí odkaz:
https://doaj.org/article/cea912f1e89a4f84abff5a83f7817c33
Autor:
Mihir Parikh, Thane G. Maddaford, J. Alejandro Austria, Michel Aliani, Thomas Netticadan, Grant N. Pierce
Publikováno v:
Nutrients, Vol 11, Iss 5, p 1171 (2019)
Flaxseed is a rich source of the omega-3 fatty acid, alpha linolenic acid, the lignan secoisolariciresinol diglucoside and fiber. These compounds provide bioactivity of value to the health of animals and humans through their anti-inflammatory action,
Externí odkaz:
https://doaj.org/article/742b1298757e4a99a049cc22daf6f51a
Publikováno v:
Molecules, Vol 24, Iss 8, p 1509 (2019)
Food quality and nutritional habits strongly influence human health status. Extensive research has been conducted to confirm that foods rich in biologically active nutrients have a positive impact on the onset and development of different pathologica
Externí odkaz:
https://doaj.org/article/dd2bb55b6c844d9b8b5ab19d55a6c7bb
Autor:
Mihir Parikh, Pema Raj, Liping Yu, Jo-Ann Stebbing, Suvira Prashar, Jay C. Petkau, Paramjit S. Tappia, Grant N. Pierce, Yaw L. Siow, Dan Brown, Heather Blewett, Thomas Netticadan
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 983 (2019)
The cardioprotective effects of ginseng root extracts have been reported. However, nothing is known about the myocardial actions of the phenolic compounds enriched in ginseng berry. Therefore, this study was undertaken to investigate the effects of A
Externí odkaz:
https://doaj.org/article/6d84df607efc4f1dbf6ff46ef0b9d692