Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mihir B Doshi"'
Autor:
Andrew L Hong, Yuen-Yi Tseng, Jeremiah A Wala, Won-Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles WM Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William C Hahn
Publikováno v:
eLife, Vol 8 (2019)
Renal medullary carcinoma (RMC) is a rare and deadly kidney cancer in patients of African descent with sickle cell trait. We have developed faithful patient-derived RMC models and using whole-genome sequencing, we identified loss-of-function intronic
Externí odkaz:
https://doaj.org/article/ea9c3a1d96864bb8bbdbc626e575f019
Autor:
Namgyu Lee, Sung Jin Park, Mike Lange, Tenzin Tseyang, Mihir B. Doshi, Tae Yong Kim, Yoseb Song, Dong In Kim, Paul L. Greer, James A. Olzmann, Jessica B. Spinelli, Dohoon Kim
The canonical biological function of selenium is in the production of selenocysteine residues of selenoproteins, and this forms the basis for its role as an essential antioxidant and cytoprotective micronutrient. Here, we demonstrate that selenium, v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238be02ad131d1d3798fc4e04a2721d0
https://doi.org/10.1101/2023.04.13.535674
https://doi.org/10.1101/2023.04.13.535674
Autor:
William C. Hahn, Jonathan E. Rosenberg, Anthony Letai, Rameen Beroukhim, David J. Kwiatkowski, Rosalyn M. Adam, Amy J. Schlauch, Rebecca Modiste, Anna C. Schinzel, Won Jun Kim, Bryan D. Kynnap, Mihir B. Doshi, Jennifer L. Guerriero, Andrew L. Hong
Copy number variation (CNV) of samples in TCGA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9a8ed12e71126e7f256efe59322271
https://doi.org/10.1158/1541-7786.22512646.v1
https://doi.org/10.1158/1541-7786.22512646.v1
Autor:
William C. Hahn, Jonathan E. Rosenberg, Anthony Letai, Rameen Beroukhim, David J. Kwiatkowski, Rosalyn M. Adam, Amy J. Schlauch, Rebecca Modiste, Anna C. Schinzel, Won Jun Kim, Bryan D. Kynnap, Mihir B. Doshi, Jennifer L. Guerriero, Andrew L. Hong
DEDD and MCL1 overexpression are not necessary for initiation of tumorigenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e738a76d52fbbf3534c9e7ef0c1e5af
https://doi.org/10.1158/1541-7786.22512655
https://doi.org/10.1158/1541-7786.22512655
Autor:
William C. Hahn, Aviad Tsherniak, David E. Root, Matthew Meyerson, Todd R. Golub, Charles W. Roberts, Kimberly Stegmaier, Levi A. Garraway, Glenn S. Cowley, Gregory Kryukov, Coyin Oh, Andrew D. Cherniack, Amy Goodale, Yenarae Lee, Sasha Pantel, Guozhi Jiang, Levi D. Ali, Han Xu, Stanley Gill, Maria Kost-Alimova, Mihir B. Doshi, William F. Harrington, Gavin Ha, April Cook, Uri Ben-David, Cheng-Zhong Zhang, Francisca Vazquez, Barbara A. Weir, Robin M. Meyers, Andrew J. Aguirre
Supplementary Figure S1. Genome-scale CRISPR-Cas9 screening identifies a strong correlation between copy number and sensitivity to CRISPR-Cas9 genome editing. Supplementary Figure S2. Global summary of the relationship of CRISPR-Cas9 guide scores to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a19689f343908709fb1c22c634cf7b
https://doi.org/10.1158/2159-8290.22531296
https://doi.org/10.1158/2159-8290.22531296
Autor:
William C. Hahn, Aviad Tsherniak, David E. Root, Matthew Meyerson, Todd R. Golub, Charles W. Roberts, Kimberly Stegmaier, Levi A. Garraway, Glenn S. Cowley, Gregory Kryukov, Coyin Oh, Andrew D. Cherniack, Amy Goodale, Yenarae Lee, Sasha Pantel, Guozhi Jiang, Levi D. Ali, Han Xu, Stanley Gill, Maria Kost-Alimova, Mihir B. Doshi, William F. Harrington, Gavin Ha, April Cook, Uri Ben-David, Cheng-Zhong Zhang, Francisca Vazquez, Barbara A. Weir, Robin M. Meyers, Andrew J. Aguirre
Sample Information: Table with cell line identities and relevant information for this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e85aa9705ce87ea97e87829b5808053
https://doi.org/10.1158/2159-8290.22531287.v1
https://doi.org/10.1158/2159-8290.22531287.v1
Autor:
William C. Hahn, Jonathan E. Rosenberg, Anthony Letai, Rameen Beroukhim, David J. Kwiatkowski, Rosalyn M. Adam, Amy J. Schlauch, Rebecca Modiste, Anna C. Schinzel, Won Jun Kim, Bryan D. Kynnap, Mihir B. Doshi, Jennifer L. Guerriero, Andrew L. Hong
Focal amplification of chromosome 1q23.3 in patients with advanced primary or relapsed urothelial carcinomas is associated with poor survival. We interrogated chromosome 1q23.3 and the nearby focal amplicon 1q21.3, as both are associated with increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af212e75eaf64b3e7378fe26930013c5
https://doi.org/10.1158/1541-7786.c.6540298.v1
https://doi.org/10.1158/1541-7786.c.6540298.v1
Autor:
William C. Hahn, Aviad Tsherniak, David E. Root, Matthew Meyerson, Todd R. Golub, Charles W. Roberts, Kimberly Stegmaier, Levi A. Garraway, Glenn S. Cowley, Gregory Kryukov, Coyin Oh, Andrew D. Cherniack, Amy Goodale, Yenarae Lee, Sasha Pantel, Guozhi Jiang, Levi D. Ali, Han Xu, Stanley Gill, Maria Kost-Alimova, Mihir B. Doshi, William F. Harrington, Gavin Ha, April Cook, Uri Ben-David, Cheng-Zhong Zhang, Francisca Vazquez, Barbara A. Weir, Robin M. Meyers, Andrew J. Aguirre
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cecf82a440fa137362f858bfcadb07
https://doi.org/10.1158/2159-8290.22531290
https://doi.org/10.1158/2159-8290.22531290
Autor:
Sharon B. Cantor, Neil Johnson, Lihua J. Zhu, Bin Deng, Jianhong Ou, Matt Bere, Mihir B. Doshi, Jennifer A. Calvo, Samuel M. Bond, Sumeet U. Nayak, Michelle Mosqueda, Min Peng, Ke Cong, John J. Krais, Nicholas J. Panzarino
Defects in DNA repair and the protection of stalled DNA replication forks are thought to underlie the chemosensitivity of tumors deficient in the hereditary breast cancer genes BRCA1 and BRCA2 (BRCA). Challenging this assumption are recent findings t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06de07f4f7ad1796e1fb15bd0f3b947c
https://doi.org/10.1158/0008-5472.c.6512572.v1
https://doi.org/10.1158/0008-5472.c.6512572.v1
Autor:
Sharon B. Cantor, Neil Johnson, Lihua J. Zhu, Bin Deng, Jianhong Ou, Matt Bere, Mihir B. Doshi, Jennifer A. Calvo, Samuel M. Bond, Sumeet U. Nayak, Michelle Mosqueda, Min Peng, Ke Cong, John J. Krais, Nicholas J. Panzarino
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5154b074718c1c75fc74fd60d98c0d25
https://doi.org/10.1158/0008-5472.22427155
https://doi.org/10.1158/0008-5472.22427155