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Muramyl dipeptide (MDP, N-acetylmuramyl-L-alanyl- D-isoglutamine) is the smallest peptidoglycan fragment capable to trigger the immune response. MDP acts as a pathogen-associated molecular pattern and activates the NOD2 (Nucleotide Binding Oligomeriz
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6aee01605d817c4ef776ede025e2ab3a
https://www.bib.irb.hr/1233666
https://www.bib.irb.hr/1233666
Adjuvants or immunostimulators are substances that are added to vaccines to improve the specific human immune response to a specific antigen. Derivatives of muramyl dipeptide (MDP, N- acetylmuramyl-L-alanyl-D-isoglutamine) as well as desmuramyl dipep
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::b28f8f527f8df7c939949062142b53dc
https://www.bib.irb.hr/1162483
https://www.bib.irb.hr/1162483
Adjuvanti su tvari koje se dodaju cjepivima radi pojačavanja imunološkog odgovora. Derivati muramil-dipeptida (N-acetilmuramil-L-alanil-D-izoglutamin, MDP) kao i derivati desmuramil-dipetida (L-Ala-D-isoGln), MDP-a bez šećerne N-acetilmuraminske
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::0d36650e403011bd855f707904950363
https://www.bib.irb.hr/1128174
https://www.bib.irb.hr/1128174
Autor:
Petrović Peroković, Vesna, Car, Željka, Bušljeta, Mia, Mihelec, Danijela, Paurević, Marija, Ivanković, Siniša, Stojković, Ranko, Ribić, Rosana
Publikováno v:
International Journal of Molecular Sciences; Aug2022, Vol. 23 Issue 15, p8628-8628, 20p
Autor:
Draženović, Josip, Ožegović, Antonija, Mihelec, Danijela, Car, Željka, Škalamera, Đani, Petrović-Peroković, Vesna, Ribić, Rosana
Imunostimulatori ili adjuvanti su imunomodulatori koji ubrzavaju, pojačavaju ili produljuju imunološki odgovor na određeni antigen te se dodaju cjepivima koja nisu dovoljno imunogenična.1 Derivati muramil-dipeptida (MurNAc-L-Ala-D-isoGln, MDP) i
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::ee6b7555bddc0aaeffeda1e2d31aeef5
https://www.bib.irb.hr/1052357
https://www.bib.irb.hr/1052357
Autor:
Mihelec, Danijela
U ovome diplomskom radu opisana je priprava lipofilnih adamantilnih derivata 3-hidroksi-1- (m- hidroksifenil)-2-metilpiridin-4-ona (1) te pokušaj sinteze njegovih manoznih derivata. Spoj 1 pripravljen je direktnim postupkom iz maltola i m- hidroksia
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::687537838ec6e974eca9b781b7ff87bf
https://www.bib.irb.hr/789738
https://www.bib.irb.hr/789738
Autor:
Mihelec, Danijela
Ilid je neutralna molekula koja ima negativan i pozitivan naboj. Delokalizacija naboja kroz funkcionalne grupe omogućava klasifikaciju ilida u tri glavne grupe: stabilizirani, polustabilizirani i nestabilizirani ilidi. Postoje nekoliko metoda za sin
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::df73a5a4fde09ccfbac1cc0b9f4f158c
https://www.bib.irb.hr/644364
https://www.bib.irb.hr/644364