Zobrazeno 1 - 10 of 375 pro vyhledávání: '"Mihailov, E"'
1
Akademický článek
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
Autor: Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., Trompet, S., Cooper, R. S., Chowdhury, R., Dedoussis, G., de Faire, U., Feranil, A. B., Sheu, W. H.- H., Ferrucci, L., Freimer, N. B., Gieger, C., Sengupta, S., Grallert, H., Groop, L. C., Gudnason, V., Tanaka, T., Gyllensten, U., Hamsten, A., Erdmann, J., Harris, T. B., Shuldiner, A. R., Hingorani, A., Hirschhorn, J. N., Gravito, M. L., Wilson, J. F., Hofman, A., Hovingh, G. K., Hsiung, C. A., Humphries, S. E., Teslovich, T. M., Hunt, S. C., Hveem, K., Iribarren, C., Siegbahn, A., Groves, C. J., Nordestgaard, B. G., Njolstad, I., Jarvelin, M.-R., Jula, A., Kahonen, M., Kaprio, J., Kesaniemi, A., Kivimaki, M., Thorleifsson, G., Kooner, J. S., Hallmans, G., Koudstaal, P. J., Kuulasmaa, K., Gustafsson, S., Krauss, R. M., Kuh, D., Nielsen, S. F., Kuusisto, J., Kyvik, K. O., Laakso, M., Lakka, T. A., Hartikainen, A.-L., Lind, L., Van den Herik, E. G., Lindgren, C. M., Kanoni, S., Spector, T. D., Martin, N. G., Marz, W., McCarthy, M. I., McKenzie, C. A., Tybjaerg-Hansen, A., Assimes, T. L., Meneton, P., Metspalu, A., Moilanen, L., Morris, A. D., Ganna, A., Voight, B. F., Stefansson, K., Munroe, P. B., van Pelt, L. J., Waite, L. L., Hayward, C., Strachan, D. P., Tayo, B. O., Tremoli, E., Tuomilehto, J., Uusitupa, M., Chen, J., van Duijn, C. M., Vollenweider, P., Wallentin, L., Liu, D. J., Hernandez, D., Vedantam, S., Wareham, N. J., Jukema, J. W., Whitfield, J. B., Wolffenbuttel, B. H. R., Ordovas, J. M., Buchkovich, M. L., Boerwinkle, E., Palmer, C. N. A., Thorsteinsdottir, U., Hicks, A. A., Chasman, D. I., Rotter, J. I., Wainwright, N., Franks, P. W., Perola, M., Wong, A., Riatti, S., Mora, S., Cupples, L. A., Sandhu, M. S., Rauramaa, R., Rich, S. S., Boehnke, M., Deloukas, P., Mohlke, K. L., Wijmenga, C., Ingelsson, E., Gu, D., Roberts, R., Beckmann, J. S., Wu, Y., Peloso, G. M., Blankenberg, S., Watkins, H., Clarke, R., Collins, R., Kim, B.-J., Wild, S. H., McPherson, R., Nieminen, M. S., Barroso, I., Holm, H., O'Donnell, C., Schreiber, S., Zhang, W., Salomaa, V., Zalloua, P. A., Mannisto, S., Amouyel, P., Willemsen, G., Arveiler, D., Hung, Y.-J., Bragg-Gresham, J. L., Ferrieres, J., Muller-Nurasyid, M., Ferrario, M., Kee, F., Absher, D., Willer, C. J., Samani, N., Schunkert, H., Butterworth, A. S., Sattar, N., Wilsgaard, T., Chang, H.-Y., Howson, J. M. M., Pedersen, N. L., Di Angelantonio, E., Demirkan, A., Den Hertog, H. M., Do, R., Donnelly, L. A., Ehret, G. B., Illig, T., Esko, T., Feitosa, M. F., Ferreira, T., Been, L. F., Power, C., Fischer, K., Song, C., Fontanillas, P., Fraser, R. M., Freitag, D. F., Jones, M. R., Gurdasani, D., Heikkila, K., Hypponen, E., Isaacs, A., Jackson, A. U., Pramstaller, P. P., Johansson, A., Bolton, J. L., Young, E. H., Johnson, T., Kaleebu, P., Kaakinen, M., Kettunen, J., Kleber, M. E., Li, X., Luan, J., Lyytikainen, L.-P., Price, J. F., Magnusson, P. K. E., Mangino, M., Mihailov, E., Kastelein, J. J. P., Zhao, J. H., Bonnycastle, L. L., Montasser, M. E., Nolte, I. M., OConnell, J. R., Palmer, C. D., Petersen, A.-K., Schmidt, R. F., Sanna, S., Saxena, R., Bandinelli, S., Service, S. K., Shah, S., Adair, L. S., Shungin, D., Brambilla, P., Sidore, C., De Craen, A., Burnett, M. S., Psaty, B. M., Cesana, G., Khaw, K.-T., Dimitriou, M., Doney, A. S. F., Doring, A., Elliott, P., Epstein, S. E., Eyjolfsson, G. I., Gigante, B., Goodarzi, M. O., Quertermous, T., Kim, E., Stitziel, N. O., Volcik, K. A., Klopp, N., Komulainen, P., Kumari, M., Langenberg, C., Ford, I., Lehtimaki, T., Lin, S.-Y., Lindstrom, J., Bennett, F., Danesh, J., Loos, R. J. F., Uitterlinden, A. G., Mach, F., McArdle, W. L., Meisinger, C., Mitchell, B. D., Muller, G., Nagaraja, R., Packard, C., Narisu, N., Kathiresan, S., Nieminen, T. V. M., Bochud, M., Nsubuga, R. N., Olafsson, I., Ong, K. K., Palotie, A., Papamarkou, T., Pomilla, C., Pouta, A., Rader, D. J., Reilly, M. P., Majumder, A. a. S., Ridker, P. M., Sanghera, D. K., Boehm, B. O., Rivadeneira, F., Rudan, I., Ruokonen, A., Scharnagl, H., Seeley, J., Asiki, G., Silander, K., Stancakova, A., Stirrups, K., Swift, A. J., Saramies, J., Alam, D. S., Boomsma, D. I., Tiret, L., Strawbridge, R. J., Abecasis, G., Watson, S., Borecki, I. B., Bornstein, S. R., Bovet, P., Burnier, M., Campbell, H., Schwarz, P. E. H., Chakravarti, A., Chambers, J. C., Chen, Y.-D. I., Collins, F. S., Schmidt, E. M., Surakka, I.
Scavenger receptor BI (SR-BI) is the major receptor for high-density lipoprotein (HDL) cholesterol (HDL-C). In humans, high amounts of HDL-C in plasma are associated with a lower risk of coronary heart disease (CHD). Mice that have depleted Scarb1 (S
Externí odkaz: http://hdl.handle.net/10150/623258
http://arizona.openrepository.com/arizona/handle/10150/623258
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2
Akademický článek
The Vagueness of Integrating the Empirical and the Normative: Researchers' Views on Doing Empirical Bioethics.
Autor: Wangmo, T., Provoost, V., Mihailov, E.
Publikováno v: Journal of Bioethical Inquiry; Jun2024, Vol. 21 Issue 2, p295-308, 14p
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Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults A 2-Sample Mendelian Randomization Study
Autor: Choi, K.W., Chen, C.Y., Stein, M.B., Klimentidis, Y.C., Wang, M.J., Koenen, K.C., Smoller, J.W., Wray, N.R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E.M., Abdellaoui, A., Adams, M.J., Agerbo, E., Air, T., Andlauer, T.F.M., Bacanu, S.A., Baekvad-Hansen, M., Beekman, A.T.F., Bigdeli, T.B., Binder, E.B., Blackwood, D.H.R., Bryois, J., Buttenschon, H.N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Hvarregaard, J., Christensen, J.H., Clarke, T.K., Coleman, J.R.I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G.E., Davies, G., Deary, I.J., Degenhardt, F., Derks, E.M., Direk, N., Dolan, C.V., Dunn, E.C., Eley, T.C., Escott-Price, V., Kiadeh, F.F.H., Finucane, H.K., Forstner, A.J., Frank, J., Gaspar, H.A., Gill, M., Goes, F.S., Gordon, S.D., Grove, J., Hall, L.S., Hansen, C.S., Hansen, T.F., Herms, S., Hickie, I.B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J.J., Hougaard, D.M., Ising, M., Jansen, R., Jorgenson, E., Knowles, J.A., Kohane, I.S., Kraft, J., Kretzschmar, W., Krogh, J., Kutalik, Z., Li, Y.H., Lind, P.A., MacIntyre, D.J., MacKinnon, D.F., Maier, R.M., Marchini, J., McGrath, P., McGuffin, P., Medland, S.E., Mehta, D., Middeldorp, C.M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F.M., Montgomery, G.W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M.G., Nyholt, D.R., O'Reilly, P.F., Oskarsson, H., Owen, M.J., Painter, J.N., Pedersen, C.B., Pedersen, M.G., Peterson, R.E., Pettersson, E., Peyrot, W.J., Pistis, G., Posthuma, D., Quiroz, J.A., Qvist, P., Rice, J.P., Riley, B.P., Rivera, M., Saeed, S., Schoevers, R., Schulte, E.C., Shen, L., Shi, J.X., Shyn, S.I., Sigurdsson, E., Sinnamon, G.C.B., Smit, J.H., Smith, D.J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K.E., Teismann, H., Teumer, A., Thompson, W., Thomson, P.A., Thorgeirsson, T.E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A.G., Umbricht, D., Auwera, S. van der, Hemert, A.M. van, Viktorin, A., Visscher, P.M., Wang, Y.P., Webb, B.T., Weinsheimer, S.M., Wellmann, J., Willemsen, G., Witt, S.H., Wu, Y., Xi, H.L.S., Yang, J., Zhang, F.T., Arolt, V., Baune, B.T., Berger, K., Boomsma, D.I., Cichon, S., Dannlowski, U., Geus, E.J.C. de, DePaulo, J.R., Domenici, E., Domschke, K., Esko, T., Grabe, H.J., Hamilton, S.P., Hayward, C., Heath, A.C., Kendler, K.S., Kloiber, S., Lewis, G., Li, Q.Q.S., Lucae, S., Madden, P.A.F., Magnusson, P.K., Martin, N.G., McIntosh, A.M., Metspalu, A., Mors, O., Mortensen, P.B., Nordentoft, M., Nothen, M.M., O'Donovan, M.C., Paciga, S.A., Pedersen, N.L., Penninx, B.W.J.H., Perlis, R.H., Porteous, D.J., Potash, J.B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T.G., Stefansson, K., Tiemeier, H., Uher, R., Volzke, H., Weissman, M.M., Werge, T., Lewis, C.M., Levinson, D.F., Breen, G., Borglum, A.D., Sullivan, P.F., Major Depressive Disorder Working
Publikováno v: Choi, K W, Chen, C-Y, Stein, M B, Klimentidis, Y C, Wang, M-J, Koenen, K C, Smoller, J W & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults : A 2-Sample Mendelian Randomization Study ', JAMA Psychiatry, vol. 76, no. 4, pp. 399-408 . https://doi.org/10.1001/jamapsychiatry.2018.4175
JAMA Psychiatry, 76(4), 399-408. AMER MEDICAL ASSOC
JAMA Psychiatry, 76(4), 399-408. American Medical Association
Choi, K W, Chen, C Y, Stein, M B, Klimentidis, Y C, Wang, M J, Koenen, K C, Smoller, J W & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Assessment of bidirectional relationships between physical activity and depression among adults : A 2-Sample Mendelian Randomization Study ', JAMA Psychiatry, vol. 76, no. 4, pp. 399-408 . https://doi.org/10.1001/jamapsychiatry.2018.4175
JAMA psychiatry, 76(4), 399-408. American Medical Association
Choi, K W, Abdellaoui, A, Beekman, A T F, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Posthuma, D, Willemsen, G, Boomsma, D I, de Geus, E J C, Penninx, B W J H, Sullivan, P F & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study ', JAMA Psychiatry, vol. 76, no. 4, pp. 399-408 . https://doi.org/10.1001/jamapsychiatry.2018.4175
Importance: Increasing evidence shows that physical activity is associated with reduced risk for depression, pointing to a potential modifiable target for prevention. However, the causality and direction of this association are not clear; physical ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab17463265a7b6c32312b9668ae25c3a
https://hdl.handle.net/1765/116928
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7
Akademický článek
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Autor: Lagou, Vasiliki, Mägi, Reedik, Hottenga, Jouke- Jan, Grallert, Harald, Perry, John R. B., Bouatia-Naji, Nabila, Marullo, Letizia, Rybin, Denis V., Jansen, Rick, Min, JL, Dimas, AS, Ulrich, Anna, Zudina, Liudmila, Gådin, Jesper R., Jiang, Longda, Faggian, Alessia, Bonnefond, Amélie, Fadista, Joao, Stathopoulou, Maria G., Isaacs, Aaron, Willems, Sara M., Navarro, Pau, Tanaka, Toshiko, Jackson, Anne U., Montasser, May E., O’Connell, Jeff R., Bielak, Lawrence F., Webster, Rebecca J., Saxena, Richa, Stafford, Jeanette M., Pourcain, Beate St, Timpson, Nicholas J., Salo, Perttu, Shin, SY, Amin, Najaf, Smith, Albert V., Li, G, Verweij, Niek, Goel, Anuj, Ford, Ian, Johnson, Paul C. D., Johnson, Toby, Kapur, Karen, Thorleifsson, Gudmar, Strawbridge, Rona J., Rasmussen-Torvik, Laura J., Esko, Tõnu, Mihailov, E, Fall, Tove, Fraser, Ross M, Mahajan, Anubha, Kanoni, Stavroula, Giedraitis, Vilmantas, Kleber, Marcus E., Silbernagel, Günther, Meyer, Julia, Müller-Nurasyid, Martina, Ganna, Andrea, Sarin, Antti-Pekka, Yengo, Loic, Shungin, D, Luan, Jian’an, Horikoshi, Momoko, An, Ping, Sanna, Serena, Boettcher, Yvonne, Rayner, Nigel W, Nolte, Ilja M., Zemunik, Tatijana, Iperen, Erik van, Kovacs, Peter, Hastie, Nicholas D., Wild, Sarah H., McLachlan, Stela, Campbell, Susan, Polasek, Ozren, Carlson, Olga, Egan, Josephine, Kiess, Wieland, Willemsen, Gonneke, Kuusisto, Johanna, Laakso, Markku, Dimitriou, M, Hicks, Andrew A., Rauramaa, Rainer, Bandinelli, Stefania, Thorand, Barbara, Liu, Yongmei, Miljkovic, Iva, Lind, Lars, Doney, Alex, Perola, Markus, Hingorani, Aroon, Kivimaki, Mika, Kumari, Meena, Bennett, Amanda J., Groves, Christopher J., Herder, Christian, Koistinen, Heikki A., Kinnunen, Leena, Faire, Ulf de, Bakker, Stephan J. L., Uusitupa, Matti, Palmer, Colin N. A., Jukema, J. Wouter, Sattar, Naveed, Pouta, Anneli, Snieder, Harold, Boerwinkle, Eric, Pankow, James S., Magnusson, Patrik K., Krus, Ulrika, Scapoli, Chiara, de Geus, Eco J. C. N., Blüher, Matthias, Wolffenbuttel, Bruce H. R., Province, Michael A., Abecasis, Goncalo R., Meigs, James B., Hovingh, G. Kees, Lindström, Jaana, Wilson, JF, Wright, Alan F., Dedoussis, George, Bornstein, Stefan R., Schwarz, Peter E. H., Tönjes, Anke, Winkelmann, Bernhard R., Boehm, Bernhard O., März, Winfried, Metspalu, Andres, Price, Jackie F., Deloukas, Panos, Körner, Antje, Lakka, Timo A., Keinanen-Kiukaanniemi, Sirkka M., Saaristo, Timo E., Bergman, Richard N., Tuomilehto, Jaakko, Wareham, Nick, Langenberg, Claudia, Männistö, Satu, Franks, Paul W, Hayward, Caroline, Vitart, Veronique, Kaprio, Jaakko, Visvikis-Siest, Sophie, Balkau, Beverley, Altshuler, D, Rudan, Igor, Stumvoll, Michael, Campbell, Harry, van Duijn, Cornelia M., Gieger, Christian, Illig, Thomas, Ferrucci, Luigi, Pedersen, Nancy L., Pramstaller, Peter P., Boehnke, Michael, Frayling, TM, Shuldiner, Alan R., Peyser, Patricia A., Kardia, Sharon L. R., Palmer, Lyle J., Penninx, Brenda W., Meneton, Pierre, Harris, Tamara B., Navis, Gerjan, Harst, Pim van der, Smith, George Davey, Forouhi, Nita G., Loos, Ruth J. F., Salomaa, Veikko, Soranzo, Nicole, Boomsma, Dorret I., Groop, L, Tuomi, Tiinamaija, Hofman, Albert, Munroe, Patricia B., Gudnason, Vilmundur, Siscovick, David S., Watkins, Hugh, Lecoeur, Cecile, Vollenweider, Peter, Franco-Cereceda, Anders, Eriksson, Per, Jarvelin, Marjo-Riitta, Stefansson, Kari, Hamsten, Anders, Nicholson, George, Karpe, Fredrik, Dermitzakis, Emmanouil T., Lindgren, Cecilia M., McCarthy, Mark I., Froguel, Philippe, Kaakinen, Marika A., Lyssenko, Valeriya, Watanabe, Richard M., Ingelsson, Erik, Florez, Jose C., Dupuis, Josée, Barroso, I, Morris, Andrew P., Prokopenko, Inga
Externí odkaz: https://hdl.handle.net/11250/2991366
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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
Autor: Erzurumluoglu, AM, Liu, M, Jackson, VE, Barnes, DR, Datta, G, Melbourne, CA, Young, R, Batini, C, Surendran, P, Jiang, T, Adnan, SD, Afaq, S, Agrawal, A, Altmaier, E, Antoniou, AC, Asselbergs, FW, Baumbach, C, Beirut, L, Bertelsen, S, Boehnke, M, Bots, ML, Brazel, DM, Chambers, JC, Chang-Claude, J, Chen, C, Corley, J, Chou, Y-L, David, SP, de Boer, RA, de Leeuw, CA, Dennis, JG, Dominiczak, AF, Dunning, AM, Easton, DF, Eaton, C, Elliott, P, Evangelou, E, Faul, JD, Foroud, T, Goate, A, Gong, J, Grabe, HJ, Haessler, J, Haiman, C, Hallmans, G, Hammerschlag, AR, Harris, SE, Hattersley, A, Heath, A, Hsu, C, Iacono, WG, Kanoni, S, Kapoor, M, Kaprio, J, Kardia, SL, Karpe, F, Kontto, J, Kooner, JS, Kooperberg, C, Kuulasmaa, K, Laakso, M, Lai, D, Langenberg, C, Le, N, Lettre, G, Loukola, A, Luan, J, Madden, PAF, Mangino, M, Marioni, RE, Marouli, E, Marten, J, Martin, NG, McGue, M, Michailidou, K, Mihailov, E, Moayyeri, A, Moitry, M, Müller-Nurasyid, M, Naheed, A, Nauck, M, Neville, MJ, Nielsen, SF, North, K, Perola, M, Pharoah, PDP, Pistis, G, Polderman, TJ, Posthuma, D, Poulter, N, Qaiser, B, Rasheed, A, Reiner, A, Renström, F, Rice, J, Rohde, R, Rolandsson, O, Samani, NJ, Samuel, M, Schlessinger, D, Scholte, SH, Scott, RA, Sever, P, Shao, Y, Shrine, N, Smith, JA, Starr, JM, Stirrups, K, Stram, D, Stringham, HM, Tachmazidou, I, Tardif, J-C, Thompson, DJ, Tindle, HA, Tragante, V, Trompet, S, Turcot, V, Tyrrell, J, Vaartjes, I, van der Leij, AR, van der Meer, P, Varga, TV, Verweij, N, Völzke, H, Wareham, NJ, Warren, HR, Weir, DR, Weiss, S, Wetherill, L, Yaghootkar, H, Yavas, E, Jiang, Y, Chen, F, Zhan, X, Zhang, W, Zhao, W, Zhou, K, Amouyel, P, Blankenberg, S, Caulfield, MJ, Chowdhury, R, Cucca, F, Deary, IJ, Deloukas, P, Di Angelantonio, E, Ferrario, M, Ferrières, J, Franks, PW, Frayling, TM, Frossard, P, Hall, IP, Hayward, C, Jansson, J-H, Jukema, JW, Kee, F, Männistö, S, Metspalu, A, Munroe, PB, Nordestgaard, BG, Palmer, CNA, Salomaa, V, Sattar, N, Spector, T, Strachan, DP, Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ Consortium, van der Harst, P, Zeggini, E, Saleheen, D, Butterworth, AS, Wain, LV, Abecasis, GR, Danesh, J, Tobin, MD, Vrieze, S, Liu, DJ, Howson, JMM
Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking behaviour-related traits. We tes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2dcc9e0cb996255a99cde2618200dfa2
https://openaccess.sgul.ac.uk/id/eprint/110459/20/s41380-018-0313-0.pdf
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