Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mihail Y. Mastakov"'
Publikováno v:
Molecular Therapy. 5:371-380
Recombinant adeno-associated viruses (rAAVs) are among the most promising vectors for gene delivery into the CNS. However, a major hurdle for gene transfer to the mammalian brain is to achieve high transduction levels in target cells beyond the immed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f2c828ab2dc72acb81f7176dc90ceb
https://doi.org/10.1006/mthe.2002.0564
https://doi.org/10.1006/mthe.2002.0564
Autor:
Robert M. Kotin, C. Wymond Symes, Matthew J. During, Mihail Y. Mastakov, Claudia B. Leichtlein, Kristin Baer
Recombinant adeno-associated viruses (rAAV) are highly efficient vectors for gene delivery into the central nervous system (CNS). However, host inflammatory and immune responses may play a critical role in limiting the use of rAAV vectors for gene th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30febaa11262073e6bbb519fa3d857c4
https://cronfa.swan.ac.uk/Record/cronfa1345
https://cronfa.swan.ac.uk/Record/cronfa1345
Recombinant adeno-associated viruses (rAAV) are highly efficient vectors for gene transfer into the central nervous system (CNS). However, a major hurdle for gene delivery to the mammalian brain is to achieve high-level transduction in target cells b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da5e70ebd61de6dea3181441c121e82
https://cronfa.swan.ac.uk/Record/cronfa1346
https://cronfa.swan.ac.uk/Record/cronfa1346
Autor:
Paola Leone, Deborah Young, Mike Dragunow, P. Lawlor, K L Choi, Q Chen, Matthew J. During, Alexandre Mouravlev, Bridget Dicker, Christopher G. Janson, Helen L. Fitzsimons, Ruian Xu, Mihail Y. Mastakov, H Ma
Publikováno v:
Gene therapy. 8(17)
This study compared a range of mammalian CNS expression cassettes in recombinant adeno-associated virus (AAV-2) vectors using strong endogenous promoter sequences, with or without a strong post-regulatory element and polyadenylation signal. Changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d9843259af90c479488aa466ceefa9
https://pubmed.ncbi.nlm.nih.gov/11571569
https://pubmed.ncbi.nlm.nih.gov/11571569