Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Mihai Harza"'
Autor:
Cristian Surcel, Robert Dotzauer, Cristian Mirvald, Calin Popa, Cosmin Olariu, Catalin Baston, Mihai Harza, Constantin Gangu, Igor Tsaur, Ioanel Sinescu
Publikováno v:
Therapeutic Advances in Urology, Vol 16 (2024)
Background: En bloc removal of the kidney with tumor thrombus excision in a multidisciplinary team remains the standard treatment for renal cell carcinoma (RCC) with tumor thrombus extension. In order to minimize the hemodynamic impact of the surgica
Externí odkaz:
https://doaj.org/article/a9127dd4d45e46cbb51d5fb5cbc131a0
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Purpose: To prospectively determine the efficacy of naptumomab estafenatox (Nap) + IFNα versus IFN in metastatic renal cell carcinoma (RCC).Experimental Design: In a randomized, open-label, multicenter, phase II/III study, 513 patients with RCC rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32207290e588e558aa5fdbb5a6380aba
https://doi.org/10.1158/1078-0432.c.6523545.v1
https://doi.org/10.1158/1078-0432.c.6523545.v1
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Cox regression analysis with interaction between baseline covariates and treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6468db6e39fda0878203f9bffcc2ae57
https://doi.org/10.1158/1078-0432.22457241.v1
https://doi.org/10.1158/1078-0432.22457241.v1
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Anti-SEA/E-120 concentration in ITT and the subgroup SG at baseline and immediately before Nap cycle 2 (week 9), before Nap cycle 3 (week 17) and at week 25. Median{plus minus}SE is depicted.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d0d873a396743058269943cbaa358b
https://doi.org/10.1158/1078-0432.22457256
https://doi.org/10.1158/1078-0432.22457256
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Overlapping anti-SEA/E-120 windows in Moving median and adapted Subpopulation Treatment Effect Pattern Plot (STEPP) analysis. Anti-SEA/E-120 by blocks where min, median and max values are depicted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6427280763ab96ad4a657a124f96ae
https://doi.org/10.1158/1078-0432.22457265
https://doi.org/10.1158/1078-0432.22457265
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Anti-SEA/E-120 vs exposure of Nap. Concentration of Nap after Nap at day 1 of treatment. Moving median of 8 overlapping subgroups of patients with different baseline anti-SEA/E-120 (pmol/mL). Median{plus minus}SE is depicted.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f8f6a13b3a3a7cceaad1fce6213868
https://doi.org/10.1158/1078-0432.22457262
https://doi.org/10.1158/1078-0432.22457262
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Anti-SEA/E-120 vs IL-2 day 1 3h. Concentration of induced IL-2 after Nap at day 1 of treatment. Moving median of 8 overlapping subgroups of patients with different baseline anti-SEA/E-120 (pmol/mL). Median{plus minus}SE is depicted.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5fa95bce3b6baf7231a1b2fc636d5d
https://doi.org/10.1158/1078-0432.22457250
https://doi.org/10.1158/1078-0432.22457250
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Cytokine response after Nap treatment in ITT and the subgroup SG patients during cycle 1 (week 1), cycle 2 (week 9) and cycle 3 (week 17). IL-2 (A). IL-6 (B). IL-10 (C). IFN-ϒ (D). TNF-α (E). Geomean{plus minus}SE is depicted.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42330a8cb984c55e15501c45f94f5ba5
https://doi.org/10.1158/1078-0432.22457253.v1
https://doi.org/10.1158/1078-0432.22457253.v1
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Cox regression analyses with three way interaction stratified by either MSKCC or HENG risk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324b7e8c93d7bc3c8598160f40f572ad
https://doi.org/10.1158/1078-0432.22457244
https://doi.org/10.1158/1078-0432.22457244
Autor:
Timothy Eisen, Örjan Nordle, Goran Forsberg, Gunnar Hedlund, Rustem Khasanov, Oleg Karyakin, Petr Karlov, Igor Bondarenko, Serhii Polenkov, Mihai Harza, Tosho Ganev, Oleg Gladkov, Vladimir Bondar, Yaroslav Shparyk, Martin Gore, Robert E. Hawkins
Baseline anti-SEA/E-120 and plasma concentration of Nap Day 1 at 1h in different territories.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d66debe2f70a7c7f3b6788b5dbd7a75
https://doi.org/10.1158/1078-0432.22457247
https://doi.org/10.1158/1078-0432.22457247