Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Mihaela-Rita Mihailescu"'
Publikováno v:
ACS Omega, Vol 9, Iss 34, Pp 36148-36164 (2024)
Externí odkaz:
https://doaj.org/article/4adb9bf7c64a4cdab71a2823b86d5146
Autor:
Morgan Shine, Sarah E. Harris, Kendy A. Pellegrene, Adam H. Kensinger, Mihaela Rita Mihailescu, Jeffrey D. Evanseck, Patrick E. Lackey
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 469-481 (2023)
Histone mRNA degradation is controlled by the unique 3’ stem-loop of histone mRNA and the stem-loop binding protein (SLBP). As part of this process, the 3’ stem-loop is trimmed by the histone-specific 3’ exonuclease (3’hExo) and uridylated by
Externí odkaz:
https://doaj.org/article/b925eb4193f543169eda435f71228798
Autor:
Joseph A. Makowski, Adam H. Kensinger, Caylee L. Cunningham, Caleb J. Frye, Morgan Shine, Patrick E. Lackey, Mihaela Rita Mihailescu, Jeffrey D. Evanseck
Publikováno v:
ACS Physical Chemistry Au, Vol 3, Iss 5, Pp 434-443 (2023)
Externí odkaz:
https://doaj.org/article/2d7f187ab20f45b2ab853bce661dc4a7
Autor:
Joshua A. Imperatore, Damian S. McAninch, Arielle N. Valdez-Sinon, Gary J. Bassell, Mihaela Rita Mihailescu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Fused in sarcoma (FUS), identified as the heterogeneous nuclear ribonuclear protein P2, is expressed in neuronal and non-neuronal tissue, and among other functions, has been implicated in messenger RNA (mRNA) transport and possibly local translation
Externí odkaz:
https://doaj.org/article/051afea0607741cabf4cd9736d900473
Autor:
Adam H. Kensinger, Joseph A. Makowski, Kendy A. Pellegrene, Joshua A. Imperatore, Caylee L. Cunningham, Caleb J. Frye, Patrick E. Lackey, Mihaela Rita Mihailescu, Jeffrey D. Evanseck
Publikováno v:
ACS Physical Chemistry Au. 3:30-43
The functional role of the highly conserved stem-loop II motif (s2m) in SARS-CoV and SARS-CoV-2 in the viral lifecycle remains enigmatic and an intense area of research. Structure and dynamics of the s2m are key to establishing a structure-function c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9a4b3c610114edd64d566fdb8b0868
https://doi.org/10.1021/acsphyschemau.2c00032
https://doi.org/10.1021/acsphyschemau.2c00032
Autor:
Brett DeMarco, Snezana Stefanovic, Allison Williams, Kathryn R Moss, Bart R Anderson, Gary J Bassell, Mihaela Rita Mihailescu
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217275 (2019)
Fragile X syndrome, the most common inherited form of intellectual disability, is caused by the CGG trinucleotide expansion in the 5'-untranslated region of the Fmr1 gene on the X chromosome, which silences the expression of the fragile X mental reta
Externí odkaz:
https://doaj.org/article/21419c285934444e9b599f540b21e554
Publikováno v:
bioRxiv
The 2019 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has marked the spread of a novel human coronavirus. While the viral life cycle is well understood, most of the interactions at the virus-host interface rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97582103f0dfde55a6be2e5e8a1fee8
https://doi.org/10.1101/2023.05.18.541401
https://doi.org/10.1101/2023.05.18.541401
Autor:
Caylee L. Cunningham, Caleb J. Frye, Joseph A. Makowski, Adam H. Kensinger, Morgan Shine, Ella J. Milback, Patrick E. Lackey, Jeffrey D. Evanseck, Mihaela-Rita Mihailescu
Publikováno v:
bioRxiv
The stem loop 2 motif (s2m), a highly conserved 41-nucleotide hairpin structure in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome, serves as an attractive therapeutic target that may have important roles in the virus life cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e30e35df0c69297718d7df1263af25
https://doi.org/10.1101/2023.02.10.528014
https://doi.org/10.1101/2023.02.10.528014
Autor:
Caleb J. Frye, Morgan Shine, Joseph A. Makowski, Adam H. Kensinger, Caylee L. Cunningham, Ella J. Milback, Jeffrey D. Evanseck, Patrick E. Lackey, Mihaela Rita Mihailescu
Publikováno v:
Journal of Medical Virology. 95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b9ddafb1e03b8e6690115066ee843d
https://doi.org/10.1002/jmv.28467
https://doi.org/10.1002/jmv.28467
Autor:
Joshua A Imperatore, Caylee L Cunningham, Kendy A Pellegrene, Robert G Brinson, John P Marino, Jeffrey D Evanseck, Mihaela Rita Mihailescu
Publikováno v:
Nucleic Acids Research
The ongoing COVID-19 pandemic highlights the necessity for a more fundamental understanding of the coronavirus life cycle. The causative agent of the disease, SARS-CoV-2, is being studied extensively from a structural standpoint in order to gain insi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bd81b034dec1e63515faf89db5a7f3
http://europepmc.org/articles/PMC8789046
http://europepmc.org/articles/PMC8789046