Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mihaela Loredana Vlad"'
Autor:
Alexandru Filippi, Alina Constantin, Nicoleta Alexandru, Cristina Ana Mocanu, Mihaela Loredana Vlad, Ioana Madalina Fenyo, Agneta Simionescu, Dan Teodor Simionescu, Ileana Manduteanu, Adriana Georgescu
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1077 (2022)
The number and function of endothelial progenitor cells (EPCs) are reduced in diabetes, contributing to deteriorated vascular repair and the occurrence of cardiovascular complications. Here, we present the results of treating early diabetic dyslipide
Externí odkaz:
https://doaj.org/article/43fde9ec37ff44a99e1ccb6c12d7926f
Autor:
Simona-Adriana Manea, Mihaela-Loredana Vlad, Alexandra-Gela Lazar, Horia Muresian, Maya Simionescu, Adrian Manea
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2382 (2022)
Dysregulated epigenetic mechanisms promote transcriptomic and phenotypic alterations in cardiovascular diseases. The role of histone methylation-related pathways in atherosclerosis is largely unknown. We hypothesize that lysine-specific demethylase 1
Externí odkaz:
https://doaj.org/article/1e1de9347e21402abd50c0a8ada04168
Autor:
Sergiu Cecoltan, Letitia Ciortan, Razvan D. Macarie, Mihaela Vadana, Andreea C. Mihaila, Monica Tucureanu, Mihaela-Loredana Vlad, Ionel Droc, Mihaela Gherghiceanu, Agneta Simionescu, Dan Teodor Simionescu, Elena Butoi, Ileana Manduteanu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Valvular endothelial cells (VEC) have key roles in maintaining valvular integrity and homeostasis, and dysfunctional VEC are the initiators and major contributors to aortic valve disease in diabetes. Previous studies have shown that HG st
Externí odkaz:
https://doaj.org/article/3e40bb1634e842aab75c613b393ecb72
Autor:
Alexandra-Gela Lazar, Mihaela-Loredana Vlad, Adrian Manea, Maya Simionescu, Simona-Adriana Manea
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1356 (2021)
Accumulating evidence implicates the histone acetylation-based epigenetic mechanisms in the pathoetiology of diabetes-associated micro-/macrovascular complications. Diabetic kidney disease (DKD) is a progressive chronic inflammatory microvascular dis
Externí odkaz:
https://doaj.org/article/32c9854163a94f8cb604c1e5802f6a24
Autor:
Maya Simionescu, Simona-Adriana Manea, Daniela Rebleanu, A.G. Lazar, Adrian Manea, Manuela Calin, Ioana Madalina Fenyo, Mihaela-Loredana Vlad
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Excessive production of reactive oxygen species (ROS) and the ensuing oxidative stress are instrumental in all phases of atherosclerosis. Despite the major achievements in understanding the regulatory pathways and molecular sources of ROS in the vasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee43390c914480c3cd9d397baa2d9d6
https://doi.org/10.1155/2021/6685612
https://doi.org/10.1155/2021/6685612
Autor:
Monica Raicu, Horia Muresian, Mihaela-Loredana Vlad, Adrian Manea, Maya Simionescu, A.G. Lazar, Simona-Adriana Manea
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Histone acetylation plays a major role in epigenetic regulation of gene expression. Monocyte-derived macrophages express functional NADPH oxidase 5 (Nox5) that contributes to oxidative stress in atherogenesis. The mechanisms of Nox5 regulation are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ea8e5ca9211fc93e3699730868fd84
https://doaj.org/article/6c2e82603c0d42fab4d3aec621a198be
https://doaj.org/article/6c2e82603c0d42fab4d3aec621a198be
Autor:
Horia Muresian, Adrian Manea, A.G. Lazar, Mihaela-Loredana Vlad, Maya Simionescu, Ioana Madalina Fenyo, Simona-Adriana Manea, Monica Raicu
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
NADPH oxidase (Nox)-derived reactive oxygen species (ROS) are instrumental in all inflammatory phases of atherosclerosis. Dysregulated histone deacetylase (HDAC)-related epigenetic pathways have been mechanistically linked to alterations in gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61e6e5181ae1d85fd82cbad6ec18bd5
https://doi.org/10.1016/j.redox.2019.101338
https://doi.org/10.1016/j.redox.2019.101338
Autor:
Simona-Adriana Manea, Mihaela-Loredana Vlad, Ioana Madalina Fenyo, Alexandra-Gela Lazar, Monica Raicu, Horia Muresian, Maya Simionescu, Adrian Manea
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
NADPH oxidase (Nox)-derived reactive oxygen species (ROS) are instrumental in all inflammatory phases of atherosclerosis. Dysregulated histone deacetylase (HDAC)-related epigenetic pathways have been mechanistically linked to alterations in gene expr
Externí odkaz:
https://doaj.org/article/f9222191c4894c2ea160952311591c0f