Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mihaela Flueraru"'
Autor:
Leonid L. Chepelev, Tony Durst, Mihaela Flueraru, Martin Charron, Alexandru Chichirau, William G. Willmore, L.R.C. Barclay, James S. Wright
Publikováno v:
Free Radical Biology and Medicine. 39:1368-1377
We consider the cytotoxicity and the protection against oxidative stress for members of the naphthalenediol family and the known antioxidant epigallocatechin gallate (EGCG). Compounds include the 1,2-naphthalenediol (1,2-ND), 1,4-ND, 2,3-ND, 1,8-ND,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f212edc1cc43ef556032c3b5312b6e70
https://doi.org/10.1016/j.freeradbiomed.2005.06.020
https://doi.org/10.1016/j.freeradbiomed.2005.06.020
Autor:
Leonid L. Chepelev, James S. Wright, Gordana Babic, Helmi H. Hussain, and Alexandru Chichirau, Mihaela Flueraru, Tony Durst
Publikováno v:
The Journal of Organic Chemistry. 68:7023-7032
We are attempting to develop novel synthetic antioxidants aimed at retarding the effects of free-radical induced cell damage. In this paper we discuss the design strategy and report the synthesis of seven novel antioxidants, including six catechols a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb822a05db7fd8ccca6456fdb0e70ed
https://doi.org/10.1021/jo0301090
https://doi.org/10.1021/jo0301090
Autor:
Michael O. Poulter, William G. Willmore, Martin Charron, Tony Durst, Mihaela Flueraru, Remmick So, James S. Wright
Publikováno v:
Chemical research in toxicology. 19(9)
Some members of the naphthalenediol family have been shown in previous work on PC-12 cells to act as effective antioxidants while being relatively nontoxic. In the present work, we extend that study to examine the effect of naphthalenediols on rat pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba88ea1dca6d49a92453701432d29fc
https://pubmed.ncbi.nlm.nih.gov/16978027
https://pubmed.ncbi.nlm.nih.gov/16978027
Autor:
James S. Wright, Leonid L. Chepelev, Martin Charron, Helmi H. Hussain, Alexandru Chichirau, William G. Willmore, Mihaela Flueraru, Tony Durst
Publikováno v:
Free radical biologymedicine. 38(3)
ortho-Hydroxyphenols (catechols) form a common structural unit in naturally occurring antioxidants such as polyphenols. They also show pro-oxidant characteristics which depend on their particular structure. Here we examined the acetylated versions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207eb9c3f379bc97188a9e7a8596cdf8
https://pubmed.ncbi.nlm.nih.gov/15629863
https://pubmed.ncbi.nlm.nih.gov/15629863