Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mihaela, Druta"'
Autor:
Alexandra Gyurdieva, Stefan Zajic, Ya-Fang Chang, E. Andres Houseman, Shan Zhong, Jaegil Kim, Michael Nathenson, Thomas Faitg, Mary Woessner, David C. Turner, Aisha N. Hasan, John Glod, Rosandra N. Kaplan, Sandra P. D’Angelo, Dejka M. Araujo, Warren A. Chow, Mihaela Druta, George D. Demetri, Brian A. Van Tine, Stephan A. Grupp, Gregg D. Fine, Ioanna Eleftheriadou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Biomarkers predictive of response to T cell therapy remain to be better defined. This study identifies potential predictive and pharmacodynamic markers of response to NY-ESO-1 T-cell therapy in a solid tumor that may inform lymphodepletion, cell dose
Externí odkaz:
https://doaj.org/article/96c810f6a32a4df78125147d2a952087
Autor:
Zhiyan Fu, Evita B. Henderson-Jackson, Barbara A. Centeno, Gregory Y. Lauwers, Mihaela Druta, Daniel A. Anaya, Yukihiro Nakanishi
Publikováno v:
Case Reports in Pathology, Vol 2023 (2023)
A 73-year-old man with a history of atrial myxoma and basal cell carcinoma presented with unexplained fever. Contrast-enhanced CT abdomen showed a large left hepatic lobe mass with early enhancement and delayed venous washout, concerning for hepatoce
Externí odkaz:
https://doaj.org/article/b1a1ea661588408ebd9416636892a6c8
Autor:
Hailey Krzyston, Brian Morse, Danielle Deperalta, Anupam Rishi, Roger Kayaleh, Ghassan El-Haddad, Johnna Smith, Mihaela Druta, Bela Kis
Publikováno v:
Diagnostic and Interventional Radiology, Vol 26, Iss 5, Pp 449-455 (2020)
PURPOSEThe purpose of this study was to determine the safety and efficacy of liver-directed therapies in patients with unresectable metastatic leiomyosarcoma to the liver. Liver-directed therapies included in this study were transarterial chemoemboli
Externí odkaz:
https://doaj.org/article/f996892dd7a542779f020132c6efece8
Autor:
Seth M. Pollack, Neeta Somaiah, Dejka M. Araujo, Mihaela Druta, Brian A. Van Tine, Melissa A. Burgess, Sant P. Chawla, Mahesh Seetharam, Scott H. Okuno, Chet Bohac, Michael Chen, Sergey Yurasov, Steven Attia
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4593-4602 (2020)
Abstract Background Outcomes data regarding advanced synovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL) are limited, consisting primarily of retrospective series and post hoc analyses of clinical trials. Methods In this multi‐center ret
Externí odkaz:
https://doaj.org/article/2292b5dd195549049e097c6c426bed12
Autor:
Indu Ramachandran, Daniel E. Lowther, Rebecca Dryer-Minnerly, Ruoxi Wang, Svetlana Fayngerts, Daniel Nunez, Gareth Betts, Natalie Bath, Alex J. Tipping, Luca Melchiori, Jean-Marc Navenot, John Glod, Crystal L. Mackall, Sandra P. D’Angelo, Dejka M. Araujo, Warren A. Chow, George D. Demetri, Mihaela Druta, Brian A. Van Tine, Stephan A. Grupp, Albiruni R. Abdul Razak, Breelyn Wilky, Malini Iyengar, Trupti Trivedi, Erin Van Winkle, Karen Chagin, Rafael Amado, Gwendolyn K. Binder, Samik Basu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Gene-modified autologous T cells expressing NY-ESO-1c259, an affinity-enhanced T-cell receptor (TCR) reactive against the NY-ESO-1-specific HLA-A*02-restricted peptide SLLMWITQC (NY-ESO-1 SPEAR T-cells; GSK 794), have demonstrated
Externí odkaz:
https://doaj.org/article/08dda14b5f1b4ef08600740b083a4b11
Autor:
David S. Hong, Brian A. Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L. Johnson, Anthony J. Olszanski, Jeffrey M. Clarke, Dejka Araujo, George R. Blumenschein, Partow Kebriaei, Quan Lin, Alex J. Tipping, Joseph P. Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D. Bushman, John K. Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G. Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand’Maison, Philip McCarthy, Paula M. Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A. Liebner, Kunle Odunsi, Marcus O. Butler
Publikováno v:
Nature Medicine. 29:104-114
Affinity-optimized T cell receptors can enhance the potency of adoptive T cell therapy. Afamitresgene autoleucel (afami-cel) is a human leukocyte antigen-restricted autologous T cell therapy targeting melanoma-associated antigen A4 (MAGE-A4), a cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bcb18cec08cabb466f42330474d0ce
https://doi.org/10.1038/s41591-022-02128-z
https://doi.org/10.1038/s41591-022-02128-z
Autor:
David Turner, John Glod, Alexandra Gyurdieva, Stefan Zajic, Ya-Fang Chang, E Andres Houseman, Shan Zhong, Jaegil Kim, Laura Johnson, Jenna Tress, Aisha Hasan, Victoria Chiou, Naimish Pandya, Dejka Araujo, Warren Chow, Mihaela Druta, George Demetri, Brian Van Tine
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/f169156f7e384e7ea3190d60112f28c7
Autor:
Neeta Somaiah, Sant P. Chawla, Matthew S. Block, John C. Morris, Khanh Do, Joseph W. Kim, Mihaela Druta, Kamalesh K. Sankhala, Patrick Hwu, Robin L. Jones, Sacha Gnjatic, Seunghee Kim-Schulze, Kevin Tuballes, Mahlet Yishak, Hailing Lu, Adam Yakovich, Jan Ter Meulen, Michael Chen, Richard T. Kenney, Chet Bohac, Seth M. Pollack
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Preclinical data suggest that a “prime-boost” vaccine regimen using a target-expressing lentiviral vector for priming, followed by a recombinant protein boost, may be effective against cancer; however, this strategy has not been evaluated in a cl
Externí odkaz:
https://doaj.org/article/aeaf8cf7e6dc4867be463362683d875c
Autor:
Ruoyu Miao, Jennifer Swank, Dan Melzer, Steven Ludlow, Leah Clark, Molly Finger, Damon R. Reed, Mihaela Druta, Andrew S. Brohl
Publikováno v:
Cancer Immunology, Immunotherapy.
Background Immune checkpoint inhibitors (ICIs) have shown modest antitumor activity in unselected advanced sarcomas. Histology driven approach to patient selection is the current standard for off-label anti-programmed cell death 1 (PD1) immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dbb65a2c4aa85d079740e1f73451459
https://doi.org/10.1007/s00262-023-03387-6
https://doi.org/10.1007/s00262-023-03387-6
Autor:
Gurpreet Kapoor, Stefan Zajic, Sunil Suchindran, Jaegil Kim, Uma Saxena, Aishwarya Bhaskar, Heather Kaczynski, Michael Nathenson, Jimson D'Souza, Benjamin Rich, Sandra D'Angelo, Mihaela Druta, Brian Van Tine, Neeta Somaiah, David Liebner, Scott Schuetze, Ioanna Eleftheriadou
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e345a61468fc594a656a5c54b5a416
https://doi.org/10.1136/jitc-2022-sitc2022.0601
https://doi.org/10.1136/jitc-2022-sitc2022.0601