Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Mihaela, Campan"'
1
Akademický článek
SARS-CoV-2 viral variants can rapidly be identified for clinical decision making and population surveillance using a high-throughput digital droplet PCR assay
Autor: Olivier Pernet, Maia Weisenhaus, Chrysovalantis Stafylis, Christopher Williams, Mihaela Campan, Jonas Pettersson, Nicole Green, David M. Lee, Paul D. Thomas, Pamela Ward, Howard Hu, Jeffrey D. Klausner, Andrea A. Z. Kovacs, the U. S. C. Variant Study Group
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Epidemiologic surveillance of circulating SARS-CoV-2 variants is essential to assess impact on clinical outcomes and vaccine efficacy. Whole genome sequencing (WGS), the gold-standard to identify variants, requires significant infrastructure
Externí odkaz: https://doaj.org/article/a3e275232a4b494395106d1abc82b1af
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3
Data from DNA Hypermethylation of ESR1 and PGR in Breast Cancer: Pathologic and Epidemiologic Associations
Autor: Mark E. Sherman, Montserrat Garcia-Closas, Peter W. Laird, David L. Rimm, Louise A. Brinton, Beata Peplonska, Jolanta Lissowska, Xiaohong R. Yang, Jonine D. Figueroa, Mihaela Campan, Mia M. Gaudet
Improved understanding of the etiology of estrogen receptor-α (ERα)–negative and progesterone receptor (PR)–negative breast cancers may permit improved risk prediction. In vitro studies implicate DNA hypermethylation of the ERα and PR promoter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113917fa9a1a49668dcbb2c71a446166
https://doi.org/10.1158/1055-9965.c.6514921.v1
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4
The Sulfotransferase
Autor: Candace, Johnson, Daniel J, Mullen, Suhaida A, Selamat, Mihaela, Campan, Ite A, Offringa, Crystal N, Marconett
Publikováno v: International Journal of Environmental Research and Public Health
Lung cancer is the leading cause of cancer-related death. Tobacco exposure is associated with 80–90% of lung cancer cases. The SULT1C2 sulfotransferase modifies xenobiotic compounds to enhance secretion but can also render these compounds carcinoge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4aa6caf9f5b5bb8ddc61a78c1711a383
https://pubmed.ncbi.nlm.nih.gov/35010676
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5
Akademický článek
Rapid and quantitative method of allele-specific DNA methylation analysis
Autor: Hui-Lee Wong, Hyang-Min Byun, Jennifer M. Kwan, Mihaela Campan, Sue A. Ingles, Peter W. Laird, Allen S. Yang
Publikováno v: BioTechniques, Vol 41, Iss 6, Pp 734-739 (2006)
Several biological phenomena depend on differential methylation of chromosomal strands. While understanding the role of these processes requires information on allele-specific methylation, the available methodologies are not quantitative or labor-int
Externí odkaz: https://doaj.org/article/dc855d569aff44ecb66d661c762a49b3
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6
The Sulfotransferase SULT1C2 is Epigenetically Activated and Transcriptionally Induced by Tobacco Exposure and is Associated with Patient Outcome in Lung Adenocarcinoma
Autor: Ite A. Offringa, Mihaela Campan, Candace Johnson, Daniel J. Mullen, Suhaida A. Selamat, Crystal N. Marconett
Publikováno v: International Journal of Environmental Research and Public Health, Vol 19, Iss 416, p 416 (2022)
International Journal of Environmental Research and Public Health; Volume 19; Issue 1; Pages: 416
Lung cancer is the leading cause of cancer-related death. Tobacco exposure is associated with 80–90% of lung cancer cases. The SULT1C2 sulfotransferase modifies xenobiotic compounds to enhance secretion but can also render these compounds carcinoge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458dff3d30c5eac3d2b4be44a9a1c5b1
https://doi.org/10.21203/rs.3.rs-795539/v1
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7
Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration
Autor: Peter W. Laird, Ruth M. Pfeiffer, Mark E. Sherman, Maxwell P. Lee, Clara Bodelon, Howard H. Yang, Brittny C Davis Lynn, Hannah P. Yang, Kathleen F. Arcaro, Daniel J. Weisenberger, Joshua N. Sampson, Eva P. Browne, Jeanne Murphy, Mihaela Campan, Douglas L. Anderton, Gretchen L. Gierach
Publikováno v: Cancer Prev Res (Phila)
Black women in the United States are disproportionately affected by early-onset, triple-negative breast cancer. DNA methylation has shown differences by race in healthy and tumor breast tissues. We examined associations between genome-wide DNA methyl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4dc14402045178cfe0ecc4d6e546c0c
https://doi.org/10.1158/1940-6207.capr-19-0169
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8
Akademický článek
Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer.
Autor: Christopher P E Lange, Mihaela Campan, Toshinori Hinoue, Roderick F Schmitz, Andrea E van der Meulen-de Jong, Hilde Slingerland, Peter J M J Kok, Cornelis M van Dijk, Daniel J Weisenberger, Hui Shen, Robertus A E M Tollenaar, Peter W Laird
Publikováno v: PLoS ONE, Vol 7, Iss 11, p e50266 (2012)
There is an increasing demand for accurate biomarkers for early non-invasive colorectal cancer detection. We employed a genome-scale marker discovery method to identify and verify candidate DNA methylation biomarkers for blood-based detection of colo
Externí odkaz: https://doaj.org/article/fada6eca2e264ae695fc74a84b5c1f63
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9
Abstract P6-10-07: Differences in genome-wide DNA methylation levels in breast milk by race and lactation duration
Autor: Maxwell P. Lee, Howard H. Yang, Douglas L. Anderton, Eva P. Browne, Clara Bodelon, Mark E. Sherman, Jeanne Murphy, Daniel J. Weisenberger, BC Davis Lynn, Peter W. Laird, Hannah P. Yang, Kathleen F. Arcaro, Ruth M. Pfeiffer, Gretchen L. Gierach, Mihaela Campan
Publikováno v: Cancer Research. 78:P6-10
Introduction: Identifying biomarkers of breast cancer risk among young women would have value in developing effective screening and prevention strategies at early ages. We have proposed that DNA methylation analysis of breast milk may provide breast
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0b164ec47b0ae668aa7e94d54d77e7c
https://doi.org/10.1158/1538-7445.sabcs17-p6-10-07
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10
Akademický článek
DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.
Autor: Suhaida A Selamat, Janice S Galler, Amit D Joshi, M Nicky Fyfe, Mihaela Campan, Kimberly D Siegmund, Keith M Kerr, Ite A Laird-Offringa
Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21443 (2011)
BackgroundAberrant DNA methylation is common in lung adenocarcinoma, but its timing in the phases of tumor development is largely unknown. Delineating when abnormal DNA methylation arises may provide insight into the natural history of lung adenocarc
Externí odkaz: https://doaj.org/article/b2eb146cafaf44aa9752ec800a46f547
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