Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Miha Tišler"'
Publikováno v:
Journal of Heterocyclic Chemistry. 26:1751-1754
Oxidation reactions of various methyl substituted azolopyridazines 2a-d, 3a-h, 4a,b were investigated in order to gain access to the title compounds. This procedure was found to be of limited scope affording only the carboxylic acids 5, 7 and 9. A va
Publikováno v:
Journal of Heterocyclic Chemistry. 34:1067-1098
Autor:
Miha, Tišler
Publikováno v:
Acta chimica Slovenica. 58(1)
Particular and rare examples of aromatic nucleophilic substitution are described as tele-substitution. Usually strong nucleophiles are involved and the entering group is introduced at a position distant from the expected leaving group. Examples of te
Publikováno v:
Journal of Heterocyclic Chemistry. 33:465-474
A comparative study of the reactivity of methyl groups towards N, N-dimethylformamide dimethyl acetal and tert-butoxybis(dimethylamino)methane was carried out on methyl substituted six-membered nitrogen containing heterocycles 1 to give enamines 2, w
Publikováno v:
Journal of Heterocyclic Chemistry. 32:425-434
5-(1,2,4-Triazinyl) substituted enamines 3 react with 5(4H)-oxazolones 4 in acetic anhydride to give acetylated products 5, while in toluene-acetic acid mixture nonacetylated products 9 are formed. Both types of products were isolated as (E,Z) mixtur
Autor:
Miha Tišler, Patrik Kolar
Publikováno v:
Journal of Heterocyclic Chemistry. 32:141-144
Substituted pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]imidazoles are prepared in a simple one pot reaction sequence from esters of heterocyclic or aromatic α-amino acids. The reaction involves condensation with acetoine followed by cyclization with
Publikováno v:
Journal of Heterocyclic Chemistry. 31:1259-1266
Optically active and racemic isomers of aspartic acid (1) were transformed into the corresponding N-trifluoroacetyl-5-bromo-4-oxonorvaline methyl esters (6, R = Me) and N-trifluoroacetyl-3-formylalanine methyl esters 13, which were used as starting c
Autor:
Miha Tišler, Patrik Kolar
Publikováno v:
Synthetic Communications. 24:1887-1893
A new simple synthesis of substituted pyrroles from alkyl, aryl or heteroaryl substituted α-amino acids is described. Esters of α-amino acids are first reacted with dimethyl acetylenedicarboxylate and in the in situ formed enamines are there-after
Autor:
Miha Tišler, K. Djinovic‐Carugo, Branko Stanovnik, Ljubo Golič, Ivan Leban, J. Svete, C. Tate
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 50:239-245
The molecular structures of three substituted 3-amino-2-benzoylaminopropenoic acid derivatives, methyl (Z)-2-benzoylamino-3-dimethylaminopropenoate (A), methyl (Z)-2-benzoylamino-3-(4,6-dimethyl-2-pyrimidinylamino)propenoate (B) and N-[(Z)-2-benzoyla
Publikováno v:
Journal of Heterocyclic Chemistry. 31:199-203
2-Alkoxy-4-heteroarylaminomethylene-5(4H)-thiazolones 4 were converted with various nucleophiles into β-heteroarylamino-α,β-dehydro-α-amino acid derivatives 11, 14, 15, 16, 17, 18, and 19. Reduction of 4 with sodium borohydride in ethanol saturat