Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis

Autor: Pamela Uribe, María E Cabrillana, Miguel W Fornés, Favián Treulen, Rodrigo Boguen, Vladimir Isachenko, Evgenia Isachenko, Raúl Sánchez, Juana V Villegas

Publikováno v: Asian Journal of Andrology, Vol 20, Iss 6, Pp 600-607 (2018)

Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, its ability to trigger cel

Externí odkaz: https://doaj.org/article/b92ca59a5ef9494883cd17dc611715cf

Manchette-acrosome disorders during spermiogenesis and low efficiency of seminiferous tubules in hypercholesterolemic rabbit model.

Autor: Layla Simón, Abi K Funes, Martín A Yapur, María E Cabrillana, María A Monclus, Paola V Boarelli, Amanda E Vincenti, Tania E Saez Lancellotti, Miguel W Fornés

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0172994 (2017)

Hypercholesterolemia is a marker for several adult chronic diseases. Recently we demonstrated that sub/infertility is also associated to Hypercholesterolemia in rabbits. Seminal alterations included: abnormal sperm morphology, decreased sperm number

Externí odkaz: https://doaj.org/article/dbed43ee57174d15a845d91d0e0fb14f

Semen quality and sperm function loss by hypercholesterolemic diet was recovered by addition of olive oil to diet in rabbit.

Autor: Tania E Saez Lancellotti, Paola V Boarelli, Aida A Romero, Abi K Funes, Macarena Cid-Barria, María E Cabrillana, María A Monclus, Layla Simón, Amanda E Vicenti, Miguel W Fornés

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e52386 (2013)

Fat increment (0.05% cholesterol, chol) in standard diet promoted a significant increase in serum and sperm membrane chol, which ultimately altered membrane-coupled sperm specific functions: osmotic resistance, acrosomal reaction, and sperm capacitat

Externí odkaz: https://doaj.org/article/67093215fb4e4530a0fd12d4019f5fdd

A Mouse Model of Diet-Induced Obesity Resembling Most Features of Human Metabolic Syndrome

Autor: Miguel W. Fornés, Sandra E. Gomez Mejiba, Dario C. Ramirez, Marcos D. Muñoz, Maria Cecilia Della Vedova, Maria G. Plateo-Pignatari, Nidia N. Gomez, Silvina Lis García, Maria Jose Germano, Lucas Damián Santillán, Martin Rinaldi Tosi

Publikováno v: Nutrition and Metabolic Insights, Vol 2016, Iss 9, Pp 93-102 (2016)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nutrition and Metabolic Insights
Nutrition and Metabolic Insights, Vol 9 (2016)

Increased chicken-derived fat and fructose consumption in the human diet is paralleled by an increasing prevalence of obesity and metabolic syndrome (MS). Herein, we aimed at developing and characterizing a mouse model of diet-induced obesity (DIO) r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b912fbf11d48f4e16fa60af12f427169
http://www.la-press.com/a-mouse-model-of-diet-induced-obesity-resembling-most-features-of-huma-article-a6062

Diet-Induced Pulmonary Inflammation and Incipient Fibrosis in Mice: a Possible Role of Neutrophilic Inflammation

Autor: Sandra E. Gomez Mejiba, Dario C. Ramirez, Marcos D. Muñoz, M.C. Della Vedova, Nidia N. Gomez, F M Soler Garcia, Miguel W. Fornés

Chicken fat and fructose are added into food-processing to reduce costs and enhance acceptability; however, these additives turn food into unhealthy and hypercaloric meals. Herein we have hypothesized that chronic feeding with chicken fat and fructos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93529cc95773c02ec45f31500be8fae2
https://link.springer.com/article/10.1007/s10753-019-01051-9