Výsledky vyhledávání - "Miguel Valvano"

Akademický článek

Subfunctionalization influences the expansion of bacterial multidrug antibiotic resistance

Autor: Elena Perrin, Marco Fondi, Emanuele Bosi, Alessio Mengoni, Silvia Buroni, Viola Camilla Scoffone, Miguel Valvano, Renato Fani

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)

Abstract Background Antibiotic resistance is a major problem for human health. Multidrug resistance efflux pumps, especially those of the Resistance-Nodulation-Cell Division (RND) family, are major contributors to high-level antibiotic resistance in

Externí odkaz: https://doaj.org/article/cd36fe8f0ac8499a88b27b25899824ae

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Remodelling of the Gram-negative bacterial Kdo2-lipid A and its functional implications

Autor: Miguel Valvano

Publikováno v: Valvano, M A 2022, ' Remodelling of the Gram-negative bacterial Kdo2-lipid A and its functional implications ', Microbiology (United Kingdom) . https://doi.org/10.1099/mic.0.001159

The lipopolysaccharide (LPS) is a characteristic molecule of the outer leaflet of the Gram-negative bacterial outer membrane, which consists of lipid A, core oligosaccharide, and O antigen. The lipid A is embedded in outer membrane and provides an ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb02516b29d4fd298a23262c4934d27
https://doi.org/10.1099/mic.0.001159

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Bacterial conversion of a host weapon into a nutritional signal

Autor: Miguel Valvano

Publikováno v: Valvano, M A 2022, ' Bacterial conversion of a host weapon into a nutritional signal ', The Journal of Biological Chemistry, vol. 298, no. 11, 102600 . https://doi.org/10.1016/j.jbc.2022.102600

Bacteria engulfed by phagocytic cells must resist oxidation damage and adapt to cellular hypoxia, but the mechanisms involved in this process are not completely elucidated. Recent work by Kim et al. in the Journal of Biological Chemistry investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d134950a38a358e8921b762953fb4fb1
https://doi.org/10.1016/j.jbc.2022.102600

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The BCG dilemma: linear versus non-linear correlation models over the time of the COVID-19 pandemic

Autor: Guillermo Lopez-Campos, Christopher Hawthorne, Miguel Valvano

In this work we have analysed the use of two different correlation metrics and two different datasets, detecting differences in the extent and directionality of the correlation between COVID-19 infection and BCG immunization. Correlation between COVI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa73f191cb53bf37ea5a0ef2292dcb9
https://doi.org/10.1101/2020.06.13.20129569

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Inherent colistin resistance in Genogroups of the Enterobacter cloacae complex: epidemiological, genetic and biochemical analysis from the BSAC Resistance Surveillance Programme

Autor: Shazad Mushtaq, Rosy Reynolds, Gilmore, Michael C., Olubukola Eshu, Inmaculada García Romero, Aiysha Chaudhry, Carolyne Horner, Bartholomew, Toby L., Miguel Valvano, Magdalena Dry, John Murray, Bruno Pichon, Livermore On Behalf Of The Bsac Resistance Surveillance Committe, David M.

Publikováno v: Mushtaq, S, Reynolds, R, Gilmore, M C, Eshu, O, Garcia-Romero, I, Chaudhry, A, Horner, C, Bartholomew, T L, Valvano, M A, Dry, M, Murray, J, Pichon, B & Livermore on behalf of the BSAC Resistance Surveillance Committe, D M 2020, ' Inherent colistin resistance in Genogroups of the Enterobacter cloacae complex: epidemiological, genetic and biochemical analysis from the BSAC Resistance Surveillance Programme ', Journal of Antimicrobial Chemotherapy .
Queen's University Belfast-PURE

Background: Polymyxins have re-entered use against problem Gram-negative bacteria. Resistance rates are uncertain, with estimates confounded by selective testing. Methods: The BSAC Resistance Surveillance Programme has routinely tested colistin since

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::83c8841348b880a58b90e973ec9ac596
https://pure.qub.ac.uk/en/publications/inherent-colistin-resistance-in-genogroups-of-the-enterobacter-cloacae-complex-epidemiological-genetic-and-biochemical-analysis-from-the-bsac-resistance-surveillance-programme(5b9983c0-19dd-4b7d-a577-c71892a7aac2).html

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A Burkholderia cenocepacia gene encoding a non-functional tyrosine phosphatase is required for the delayed maturation of the bacteria-containing vacuoles in macrophages

Autor: Ángel G. Andrade, ANGEL ANDRADE, Miguel Valvano

Publikováno v: Andrade, A & Valvano, M A 2014, ' A Burkholderia cenocepacia gene encoding a non-functional tyrosine phosphatase is required for the delayed maturation of the bacteria-containing vacuoles in macrophages ', Microbiology . https://doi.org/10.1099/mic.0.077206-0

Burkholderia cenocepacia infects patients with cystic fibrosis. We have previously shown that B. cenocepacia can survive in macrophages within membrane vacuoles [B. cenocepacia-containing vacuoles (BcCVs)] that preclude fusion with the lysosome. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8004374310636480a73d200c5f5dfcfe
https://doi.org/10.1099/mic.0.077206-0

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