Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miguel Santiago-Medina"'
Autor:
Maurish Bukhari, Navneeta Patel, Rosa Fontana, Miguel Santiago-Medina, Yike Jiang, Dongmei Li, Kersi Pestonjamasp, Victoria J. Christiansen, Kenneth W. Jackson, Patrick A. McKee, Jing Yang
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113302- (2023)
Summary: During metastasis, tumor cells invade through the basement membrane and intravasate into blood vessels and then extravasate into distant organs to establish metastases. Here, we report a critical role of a transmembrane serine protease fibro
Externí odkaz:
https://doaj.org/article/9eb9fb7b177049c08be28a366975d681
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743ce17d63664bd68c63d62c235b0624
https://doi.org/10.1016/b978-0-12-821618-7.00169-3
https://doi.org/10.1016/b978-0-12-821618-7.00169-3
Autor:
Jing Yang, Miguel Santiago-Medina
Publikováno v:
Cancer discovery, vol 6, iss 5
Summary: Oudin and colleagues report a novel and specific function of MENA in mediating directional migration of breast cancer cells toward a fibronectin gradient of increasing concentration. This MENA-mediated haptotactic response depends on the bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25006170afdc892a0988f7eaacbda8d9
https://doi.org/10.1158/2159-8290.cd-16-0231
https://doi.org/10.1158/2159-8290.cd-16-0231
Autor:
Jihoon Kim, Sara A. Courtneidge, Miguel Santiago-Medina, Jing Yang, Mark A. Eckert, Thinzar M. Lwin
The Twist1 transcription factor promotes tumor invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) and invadopodia-mediated extracellular matrix (ECM) degradation. The critical transcription targets of Twist1 for mediating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b1e0142b03d79787fcdf4216cc5068
https://europepmc.org/articles/PMC5482979/
https://europepmc.org/articles/PMC5482979/
PAK–PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth
Publikováno v:
Journal of Cell Science. 126:1122-1133
Summary The roles of P21-activated kinase (PAK) in the regulation of axon outgrowth downstream of extracellular matrix (ECM) proteins are poorly understood. Here we show that PAK1–3 and PIX are expressed in the developing spinal cord and differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b5433b1beb75c6913e667eeff25fcd
https://doi.org/10.1242/jcs.112607
https://doi.org/10.1242/jcs.112607
Publikováno v:
Developmental Neurobiology. 71:901-923
Developing neurons use a combination of guidance cues to assemble a functional neural network. A variety of proteins immobilized within the extracellular matrix (ECM) provide specific binding sites for integrin receptors on neurons. Integrin receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30078b04e6a460e668c677a78705e42e
https://doi.org/10.1002/dneu.20931
https://doi.org/10.1002/dneu.20931
Autor:
James R. Bamburg, Kevin C. Flynn, Miguel Santiago-Medina, Bonnie M. Marsick, Paul C. Letourneau
Publikováno v:
Developmental Neurobiology. 70:565-588
Proper neural circuitry requires that growth cones, motile tips of extending axons, respond to molecular guidance cues expressed in the developing organism. However, it is unclear how guidance cues modify the cytoskeleton to guide growth cone pathfin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a0911b8d3c115e8127211d0670548c
https://doi.org/10.1002/dneu.20800
https://doi.org/10.1002/dneu.20800
Xenopus laevis provides a robust model system to study cellular signaling and downstream processes during development both in vitro and in vivo. Intracellular signals must function within highly restricted spatial and temporal domains to activate spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7100f83a1737b13653571fcbf72aa3f9
https://europepmc.org/articles/PMC3158960/
https://europepmc.org/articles/PMC3158960/
Publikováno v:
Journal of Cell Science. 128:e1-e1
Invadopodia and podosomes, collectively referred to as invadosomes, are F-actin-rich basal protrusions of cells that provide sites of attachment to and degradation of the extracellular matrix. Invadosomes promote the invasion of cells, ranging from m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19ce9cb741c81fea36f7dfffab7eb6c
https://doi.org/10.1242/jcs.169201
https://doi.org/10.1242/jcs.169201