Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Miguel S. Barbosa"'
Autor:
Stephanie Lipps, Miguel S. Barbosa, Bernd Stein, May S Kung Sutherland, David W. Anderson, Nandita Patnaik, Weilin Xie, Sak Khammungkune, Helen Brady, Leah M. Gayo-Fung
Publikováno v:
Cytokine. 23:1-14
Bone metabolism requires tightly coupled activities exhibited by two unique cell populations, the bone-resorbing osteoclasts and the bone-forming osteoblasts. Imbalance in the function of these two cell types can result in osteoporosis, a condition c
Publikováno v:
Journal of General Virology. 82:1147-1155
Toward understanding the temporal regulation of human cytomegalovirus (HCMV) late genes, we studied the regulation of the late gene promoter (pp28US, UL99) when outside the context of the viral genome and its response to the immediate early (IE) prot
Publikováno v:
Journal of Virology. 72:236-244
Human cytomegalovirus (HCMV) gene expression is highly cell and tissue specific. Cell factor-mediated regulatory interactions are involved in regulating the restricted expression of the HCMV major immediate-early (IE) gene (J. F. Baskar, P. P. Smith,
Autor:
Miguel S. Barbosa, Ted R. Hupp, David P. Lane, Joseph Sambrook, Fourie Anne M, Bi-Ching Sang, Mary-Jane Gething
Publikováno v:
Journal of Biological Chemistry. 272:19471-19479
Mutations within conserved regions of the tumor suppressor protein, p53, result in oncogenic forms of the protein with altered tertiary structures. In most cases, the mutant p53 proteins are selectively recognized and bound by members of the HSP70 fa
Autor:
Miguel S. Barbosa, Bi-Ching Sang
Publikováno v:
Virology. 189:448-455
We characterized the state of the viral genome and transcription of human papillomavirus 18 oncogenes, E6 and E7, in immortalized human keratinocytes. At passage 9 after transfection with HPV 18 a homogeneous population of immortal clones was present
Autor:
León F. Garcı́a-Martı́nez, Graham K. Bilter, Robert Kovelman, Miguel S. Barbosa, Jun Wu, Joe O'Neill
Publikováno v:
Analytical biochemistry. 301(1)
We developed a 96-well microtiter-plate high-throughput screening (HTS) assay for the detection of modulators of transcription. This HTS assay consists of three steps: (1) the in vitro transcription reaction; (2) modification and hybridization of RNA
Publikováno v:
The Journal of general virology. 80
Human papillomaviruses (HPVs) cause a variety of clinical manifestations, including the most prevalent viral sexually transmitted disease, genital warts. HPV-6 is found in a greater number of genital warts than any other HPV. To increase our understa
Autor:
Miguel S. Barbosa
Publikováno v:
Critical reviews in oncogenesis. 7(1-2)
Each human papillomavirus (HPV) type is genotypically distinct and infects epithelial cells at unique anatomic sites. Among the HPV types described, a subgroup is associated with genital disease and a subset of these is found in 90% of genital cancer
Autor:
Bi-Ching Sang, Miguel S. Barbosa
HPV types associated with genital disease are termed "high-risk" or "low-risk" viruses according to their prevalence in cancers. Two viral genes, E6 and E7, are invariably expressed in cervical carcinomas. The E7 gene product has been found to bind t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cc468f9c3763a0686384a3d806b5ca
https://europepmc.org/articles/PMC49856/
https://europepmc.org/articles/PMC49856/
Autor:
Miguel S. Barbosa, Felix O. Wettstein
Publikováno v:
Virology. 165:134-140
The papillomavirus E7 protein may play an important role in oncogenesis as it is the major viral protein present in human cervical cancer-derived cell lines. Because of the relevance of the cottontail rabbit papillomavirus (CRPV) system for the study