Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Miguel P. Méndez-González"'
Autor:
Miguel P. Méndez-González, David E. Rivera-Aponte, Jan Benedikt, Geronimo Maldonado-Martínez, Flavia Tejeda-Bayron, Serguei N. Skatchkov, Misty J. Eaton
Publikováno v:
Brain Sciences, Vol 10, Iss 2, p 72 (2020)
Epilepsy, characterized by recurrent seizures, affects 1% of the general population. Interestingly, 25% of diabetics develop seizures with a yet unknown mechanism. Hyperglycemia downregulates inwardly rectifying potassium channel 4.1 (Kir4.1) in cult
Externí odkaz:
https://doaj.org/article/35907673b6aa46e99c1ee02dcfdad9ba
Autor:
Zsolt Kovács, Serguei N. Skatchkov, Zsolt Szabó, Saif Qahtan, Miguel P. Méndez-González, Christian J. Malpica-Nieves, Misty J. Eaton, Julianna Kardos, László Héja
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8191
Endogenous anticonvulsant mechanisms represent a reliable and currently underdeveloped strategy against recurrent seizures and may recall novel original therapeutics. Here, we investigated whether the intensification of the astroglial Glu-GABA exchan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f3ae07976b90150248cc13621769bf
https://doi.org/10.3390/ijms23158191
https://doi.org/10.3390/ijms23158191
Autor:
Katya V. Melnik-Martínez, David E. Rivera-Aponte, Christian J Malpica-Nieves, Serguei N. Skatchkov, Flavia A Tejeda-Bayron, Misty J. Eaton, Miguel P. Méndez-González
Publikováno v:
Neuroreport
Protecting neurons from neurotoxicity is a job mainly performed by astrocytes through glutamate uptake and potassium buffering. These functions are aided principally by the Kir4.1 inwardly rectifying potassium channels located in the membrane of astr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5597696542ea41ec38088ebd8fd5f2af
https://europepmc.org/articles/PMC7127973/
https://europepmc.org/articles/PMC7127973/
Autor:
David E. Rivera-Aponte, Jan Benedikt, Misty J. Eaton, Flavia A Tejeda-Bayron, Gerónimo Maldonado-Martínez, Miguel P. Méndez-González, Serguei N. Skatchkov
Publikováno v:
Brain Sciences
Volume 10
Issue 2
Brain Sciences, Vol 10, Iss 2, p 72 (2020)
Volume 10
Issue 2
Brain Sciences, Vol 10, Iss 2, p 72 (2020)
Epilepsy, characterized by recurrent seizures, affects 1% of the general population. Interestingly, 25% of diabetics develop seizures with a yet unknown mechanism. Hyperglycemia downregulates inwardly rectifying potassium channel 4.1 (Kir4.1) in cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6cff53ca08ad52da65c65e1af2a82b
Autor:
Yaroslav M. Shuba, Astrid Zayas-Santiago, David E. Rivera-Aponte, Miguel P. Méndez-González, Misty J. Eaton, Christian J Malpica-Nieves, Aixa F. Rivera-Pagán, Serguei N. Skatchkov, Gerónimo Maldonado-Martínez, Katya V. Melnik-Martínez
Publikováno v:
Neuroscience. 384
A-kinase-anchoring proteins, AKAPs, are scaffolding proteins that associate with kinases and phosphatases, and direct them to a specific submembrane site to coordinate signaling events. AKAP150, a rodent ortholog of human AKAP79, has been extensively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92ed9f4e479539e73e0459198938383
https://pubmed.ncbi.nlm.nih.gov/29800717
https://pubmed.ncbi.nlm.nih.gov/29800717
Autor:
Liorimar Ramos-Medina, Amelia Merced, Agnes Acevedo-Canabal, Yancy Ferrer-Acosta, Alicia Landivar, María A Sosa-Lloréns, Astrid Zayas-Santiago, Aranza I. Torrado, Flavia Tejeda, Bermary Santos-Vera, Eduardo Quijano-Rivera, Ernesto Cabezas-Bou, Jennifer Colón-Mercado, Kimberleve Rolon-Reyes, Fabiola Cruz-Lopez, Ariadna Aldarondo-Hernández, Jonathan Crooke-Rosado, Luis Colón-Cruz, Zarcaly Quintero-Martinez, Miguel P. Méndez-González, Jose Otero-Rivera, María Inés De Jesús-Burgos, Christian Bravo-Rivera, Hector Bravo-Rivera, Manuel Díaz-Ríos, David E. Rivera-Aponte
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[EN] Puerto Rico is in dire need of transforming its education system to counter the current economic recession and ensure a future with talented Puerto Ricans at the forefront of scientific research and technology development. Here we present a grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d815b996a4b8670dc622ba47d392b97
http://hdl.handle.net/10251/109572
http://hdl.handle.net/10251/109572
Autor:
Gerónimo Maldonado-Martínez, Astrid Zayas-Santiago, Colin G. Nichols, Serguei N. Skatchkov, Wanda Vélez-Carrasco, Yuriy V. Kucheryavykh, Miguel P. Méndez-González, Misty J. Eaton, Luis A. Cubano
The KCNJ10 gene encoding Kir4.1 contains numerous SNPs whose molecular effects remain unknown. We investigated the functional consequences of uncharacterized SNPs (Q212R, L166Q, and G83V) on homomeric (Kir4.1) and heteromeric (Kir4.1-Kir5.1) channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1d24b686af54143c6a1f2fa0bcf139
https://europepmc.org/articles/PMC4817196/
https://europepmc.org/articles/PMC4817196/
Hyperglycemia reduces functional expression of astrocytic Kir4.1 channels and glial glutamate uptake
Autor:
Aixa F. Rivera-Pagán, Miguel P. Méndez-González, Lilia Kucheryavykh, Yuriy V. Kucheryavykh, David E. Rivera-Aponte, Misty J. Eaton, Serguei N. Skatchkov
Publikováno v:
Neuroscience. 310
Diabetics are at risk for a number of serious health complications including an increased incidence of epilepsy and poorer recovery after ischemic stroke. Astrocytes play a critical role in protecting neurons by maintaining extracellular homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91325de395a8ecdcb40b5799f6651de9
https://pubmed.ncbi.nlm.nih.gov/26404875
https://pubmed.ncbi.nlm.nih.gov/26404875