Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miguel Pérez-Aso"'
Autor:
Julia Bajsert, Valérie De Glas, Emilie Faway, Catherine Lambert de Rouvroit, Miguel Pérez-Aso, Paul W. Cook, Yves Poumay
Publikováno v:
JID Innovations, Vol 4, Iss 5, Pp 100298- (2024)
The Reconstructed Human Epidermis (RHE) model derived from epidermal keratinocytes offers an ethical and scientific alternative to animal experimentation, particularly in cutaneous toxicology and dermatological research, where the elimination of anim
Externí odkaz:
https://doaj.org/article/3c1eae6cb5be494cb4e0d23859db43a7
Autor:
Vanessa Segura, Miguel Pérez-Aso, Fermí Montó, Elena Carceller, María Antonia Noguera, John Pediani, Graeme Milligan, Ian Christie McGrath, Pilar D'Ocon
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64996 (2013)
AIMS: To compare the constitutive and agonist-dependent endosomal trafficking of α(1A)- and α(1B)-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype. METHODS: Using CypHer5 technolo
Externí odkaz:
https://doaj.org/article/18a98db5f7dc479da6aaa518089cf63d
Autor:
M. Dolores Ivorra, M. Carmen Montesinos, Nuria Carpena, Miguel Pérez-Aso, Pilar D'Ocon, Nicla Flacco
Publikováno v:
Vascular Pharmacology. 61:80-89
β-Adrenoceptors (β-ARs) modulate ERK1/2 and p38 in different cells, but little is known about the contribution of these signaling pathways to the function of β-ARs in vascular tissue. Immunoblotting analysis of rat aortic rings, primary endothelia
Autor:
Fermí Montó, Miguel Pérez-Aso, Graeme Milligan, Pilar D'Ocon, M.A. Noguera, Vanessa Segura, Domingo Barettino
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833:2322-2333
We analyzed the kinetic and spatial patterns characterizing activation of the MAP kinases ERK 1 and 2 (ERK1/2) by the three α1-adrenoceptor (α1-AR) subtypes in HEK293 cells and the contribution of two different pathways to ERK1/2 phosphorylation: p
Autor:
Miguel Pérez-Aso, M.A. Noguera, Francesc Jiménez-Altayó, Vanessa Segura, S Estrada, Ivorra, Elisabet Vila, Pilar D'Ocon, JF Seller, Nicla Flacco
Publikováno v:
British Journal of Pharmacology. 169:413-425
Background and Purpose To analyse the relative contribution of β1-, β2- and β3-adrenoceptors (Adrb) to vasodilatation in conductance and resistance vessels, assessing the role of cAMP and/or NO/cGMP signalling pathways. Experimental Approach Rat m
Autor:
Diana Vicente, Miguel Pérez-Aso, Pilar D'Ocon, M.A. Noguera, Maria Dolores Ivorra, Vanessa Segura, Jaime Parés, Nicla Flacco, John C. McGrath, Eva Serna
Publikováno v:
Pharmacology research & perspectives
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Pharmacology Research & Perspectives
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Pharmacology Research & Perspectives
The objective of this study was to determine whether the different time-course characteristics of α1-adrenoceptor-mediated contraction in arteries can be related to the subtypes involved. Contractile responses to noradrenaline (NA) were compared wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3329702bc459ae8fe23b9828779f4cdf
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4001
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4001
Autor:
M.A. Noguera, Elena Carceller, Fermí Montó, Graeme Milligan, Pilar D'Ocon, Miguel Pérez-Aso, John D. Pediani, Ian McGrath, Vanessa Segura
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64996 (2013)
PLoS ONE
PLoS ONE
AIMS: To compare the constitutive and agonist-dependent endosomal trafficking of α(1A)- and α(1B)-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype. METHODS: Using CypHer5 technolo
Autor:
María D. Valls, María Soldado, Jorge Arasa, Miguel Perez-Aso, Adrienne J. Williams, Bruce N. Cronstein, M. Antonia Noguera, M. Carmen Terencio, M. Carmen Montesinos
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Adenosine A2A receptor mediates the promotion of wound healing and revascularization of injured tissue, in healthy and animals with impaired wound healing, through a mechanism depending upon tissue plasminogen activator (tPA), a component of the fibr
Externí odkaz:
https://doaj.org/article/c8d2f273ff4446ee99617da77018caa8
Autor:
Jessica L Feig, Aranzazu Mediero, Carmen Corciulo, Hailing Liu, Jin Zhang, Miguel Perez-Aso, Laura Picard, Tuere Wilder, Bruce Cronstein
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188135 (2017)
Fibrosing diseases are a leading cause of morbidity and mortality worldwide and, therefore, there is a need for safe and effective antifibrotic therapies. Adenosine, generated extracellularly by the dephosphorylation of adenine nucleotides, ligates s
Externí odkaz:
https://doaj.org/article/150e3058fd5f4e169fc85986b8100cf6