Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Miguel Ortíz-Rentería"'
Autor:
Sara L. Morales-Lázaro, Itzel Llorente, Félix Sierra-Ramírez, Ana E. López-Romero, Miguel Ortíz-Rentería, Barbara Serrano-Flores, Sidney A. Simon, León D. Islas, Tamara Rosenbaum
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
TRPV1 channels are known to mediate pathological pain and itch. Here, the authors find a naturally occurring fatty acid, oleic acid, acts as a TRPV1 antagonist and can modulate capsaicin and histamine-mediated pain and itch response in mouse models.
Externí odkaz:
https://doaj.org/article/54aa5cbb43274e3e806447b790722427
Autor:
Ricardo González-Ramírez, Sara L. Morales-Lázaro, Sidney A. Simon, Rebeca Juárez-Contreras, Itzel Llorente, Miguel Ortíz-Rentería, León D. Islas, Marcia Hiriart, Tamara Rosenbaum, Félix Sierra-Ramírez
Publikováno v:
Proceedings of the National Academy of Sciences. 115
The Transient Receptor Potential Vanilloid 1 (TRPV1) ion channel is expressed in nociceptors where, when activated by chemical or thermal stimuli, it functions as an important transducer of painful and itch-related stimuli. Although the interaction o
Autor:
Félix Sierra-Ramírez, Itzel Llorente, Miguel Ortíz-Rentería, Sidney A. Simon, Barbara Serrano-Flores, Tamara Rosenbaum, Sara L. Morales-Lázaro, Ana E. López-Romero, León D. Islas
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is mainly found in primary nociceptive afferents whose activity has been linked to pathophysiological conditions including pain, itch and inflammation. Consequently, it is important to