Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Miguel Olivas-Aguirre"'
Publikováno v:
Cells, Vol 12, Iss 16, p 2065 (2023)
Degranulation mediated killing mechanism by NK cells is dependent on store-operated Ca2+ entry (SOCE) and has optimum at moderate intracellular Ca2+ elevations so that partial block of SOCE optimizes the killing process. In this study, we tested the
Externí odkaz:
https://doaj.org/article/0f6075c8d7b245f0a6960e22af3f35fe
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The G-protein–coupled estrogen receptor (GPER) mediates non-genomic action of estrogen. Due to its differential expression in some tumors as compared to the original healthy tissues, the GPER has been proposed as a therapeutic target. Accordingly,
Externí odkaz:
https://doaj.org/article/d278ba9d06cc4828a44797c25df68a02
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glucocorticoids (GCs) are a central component of multi-drug treatment protocols against T and B acute lymphoblastic leukemia (ALL), which are used intensively during the remission induction to rapidly eliminate the leukemic blasts. The primary respon
Externí odkaz:
https://doaj.org/article/fdbc6b34075a43adbc21245b8937c3b8
Publikováno v:
Frontiers in Plant Science, Vol 11 (2021)
This work critically discusses the direct and indirect effects of natural polyamines and their catabolites such as reactive oxygen species and γ-aminobutyric acid on the activity of key plant ion-transporting proteins such as plasma membrane H+ and
Externí odkaz:
https://doaj.org/article/db065657a14c4a34af3b43d87b92f652
Autor:
Miguel Olivas-Aguirre, Liliana Torres-López, Kathya Villatoro-Gómez, Sonia Mayra Perez-Tapia, Igor Pottosin, Oxana Dobrovinskaya
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 366 (2022)
Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent. CBD suppresses the development of cancer in both in vitro (cancer cell culture) and in vivo (xenografts in immunodefici
Externí odkaz:
https://doaj.org/article/6624975dd94b45e98e3211d949a6189d
Publikováno v:
Journal of Leukocyte Biology.
Acute lymphoblastic leukemia with the worst prognosis is related to minimal residual disease. Minimal residual disease not only depends on the individual peculiarities of leukemic clones but also reflects the protective role of the acute lymphoblasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9f3f80ae8a22d03d20edb472976a289
https://doi.org/10.1093/jleuko/qiad039
https://doi.org/10.1093/jleuko/qiad039
Autor:
Miguel Olivas-Aguirre, Jesús Pérez-Chávez, Liliana Torres-López, Arturo Hernández-Cruz, Igor Pottosin, Oxana Dobrovinskaya
Publikováno v:
Cancers; Volume 15; Issue 2; Pages: 445
ALL is a highly aggressive subtype of leukemia that affects children and adults. Glucocorticoids (GCs) are a critical component of the chemotherapeutic strategy against T-ALL. Cases of resistance to GC therapy and recurrent disease require novel stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccd45154a3eeec48975babcb2c43f8e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 204, p 204 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Anticancer activity of different phenols is documented, but underlying mechanisms remain elusive. Recently, we have shown that cannabidiol kills the cells of acute lymphoblastic leukemia (ALL) by a direct interaction with mitochondria, with their con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f713f2521713247f502d97df784e1df5
https://www.mdpi.com/1422-0067/22/1/204
https://www.mdpi.com/1422-0067/22/1/204
Publikováno v:
Journal of Leukocyte Biology. 105:935-946
Acute lymphoblastic leukemia (ALL) comprises a heterogeneous group of hematologic malignancies, arising from diverse genetic alterations in the early lymphocyte development. T-cell subtype of ALL (T-ALL) accounts for about 15% and 25% of ALL in child
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fafbf1350b52ab1653ee4f0fd6899d9
https://doi.org/10.1002/jlb.5vmr0818-330rr
https://doi.org/10.1002/jlb.5vmr0818-330rr
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Glucocorticoids (GCs) are a central component of multi-drug treatment protocols against T and B acute lymphoblastic leukemia (ALL), which are used intensively during the remission induction to rapidly eliminate the leukemic blasts. The primary respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2b841e8711cf976a5727a02ac077b0
https://doi.org/10.3389/fonc.2021.617937
https://doi.org/10.3389/fonc.2021.617937