Cachexia causes time‐dependent activation of the inflammasome in the liver

Autor: Rodrigo Xavier dasNeves, Alex S. Yamashita, Daniela M.R. Riccardi, Julia Köhn‐Gaone, Rodolfo G. Camargo, Nelson I. Neto, Daniela Caetano, Silvio P. Gomes, Felipe H. Santos, Joanna D.C.C. Lima, Miguel L. Batista Jr, José Cesar Rosa‐Neto, Paulo Sérgio Martins De Alcântara, Linda F. Maximiano, José P. Otoch, Giorgio Trinchieri, Janina E.E. Tirnitz‐Parker, Marília Seelaender

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1621-1630 (2023)

Abstract Background Cachexia is a wasting syndrome associated with systemic inflammation and metabolic disruption. Detection of the early signs of the disease may contribute to the effective attenuation of associated symptoms. Despite playing a centr

Externí odkaz: https://doaj.org/article/f9b430f22f644714b3aa90b82e11b4ad

Exercise Training as Therapeutic Approach in Cancer Cachexia: A Review of Potential Anti-inflammatory Effect on Muscle Wasting

Autor: Luana G. Leal, Magno A. Lopes, Sidney B. Peres, Miguel L. Batista

Publikováno v: Frontiers in Physiology, Vol 11 (2021)

Cachexia is a multifactorial inflammatory syndrome with high prevalence in cancer patients. It is characterized by a metabolic chaos culminating in drastic reduction in body weight, mainly due to skeletal muscle and fat depletion. Currently, there is

Externí odkaz: https://doaj.org/article/2a53eb8c31da46f4a523543e1c084f8e

Sympathetic nerve-adipocyte interactions in response to acute stress

Autor: Akiva Mintz, Vasco Azevedo, Caroline C. Picoli, Rodrigo R. Resende, Jaime Henrique Amorim, Miguel L. Batista, Alinne C. Costa, Gabryella S P Santos, Alexander Birbrair, Mauro Cunha Xavier Pinto, Niels Olsen Saraiva Câmara, Debora C. Radicchi, Sheu Oluwadare Sulaiman, Beatriz G S Rocha

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Molecular Medicine (Berlin, Germany)

Psychological stress predisposes our body to several disorders. Understanding the cellular and molecular mechanisms involved in the physiological responses to psychological stress is essential for the success of therapeutic applications. New studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472bc74a902d0ed2f5d2a530606eebfd
https://doi.org/10.1007/s00109-021-02157-0

Three-Dimensional Adipocyte Culture as a Model to Study Cachexia-Induced White Adipose Tissue Remodeling

Autor: Miguel L. Batista, Kathleen Desevin, Stephen R. Farmer, Tova Meshulam, Nabil Rabhi

Publikováno v: Journal of visualized experiments : JoVE. (167)

Cancer cachexia (CC) presents itself as a syndrome with multiple manifestations, causing a marked multi-organ metabolic imbalance. Recently, cachectic wasting has been proposed to be stimulated by several inflammatory mediators, which may disrupt the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c5cb20f0fe16aab597d79224f330ef
https://pubmed.ncbi.nlm.nih.gov/33522508

Editorial: Skeletal Muscle Immunometabolism

Autor: Miguel L. Batista, Arthur J. Cheng, Capucine Trollet, Nicolas J. Pillon, Lykke Sylow

Publikováno v: Frontiers in Physiology
Frontiers in Physiology, 2021, 12, ⟨10.3389/fphys.2021.683088⟩
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Frontiers, 2021, 12, ⟨10.3389/fphys.2021.683088⟩
Trollet, C, Cheng, A J, Sylow, L, Batista, M L & Pillon, N J 2021, ' Editorial: Skeletal muscle immunometabolism ', Frontiers in Physiology, vol. 12, 683088 . https://doi.org/10.3389/fphys.2021.683088

Skeletal muscle inflammation is triggered by multiple physiological and pathological processes. Resident immune cells such as macrophages and dendritic cells respond to the inflammatory state of skeletal muscle, and circulating immune cells can be re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a36e130efe6db8df96c2e105379b1b
https://hal.sorbonne-universite.fr/hal-03229646