Zobrazeno 1 - 10
of 8 945
pro vyhledávání: '"Miguel J."'
Autor:
Birgit Stallmeyer, Clara Bühlmann, Rytis Stakaitis, Ann-Kristin Dicke, Farah Ghieh, Luisa Meier, Ansgar Zoch, David MacKenzie MacLeod, Johanna Steingröver, Özlem Okutman, Daniela Fietz, Adrian Pilatz, Antoni Riera-Escamilla, Miguel J. Xavier, Christian Ruckert, Sara Di Persio, Nina Neuhaus, Ali Sami Gurbuz, Ahmet Şalvarci, Nicolas Le May, Kevin McEleny, Corinna Friedrich, Godfried van der Heijden, Margot J. Wyrwoll, Sabine Kliesch, Joris A. Veltman, Csilla Krausz, Stéphane Viville, Donald F. Conrad, Dónal O’Carroll, Frank Tüttelmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract piRNAs are crucial for transposon silencing, germ cell maturation, and fertility in male mice. Here, we report on the genetic landscape of piRNA dysfunction in humans and present 39 infertile men carrying biallelic variants in 14 different p
Externí odkaz:
https://doaj.org/article/f298226160c54693a03e5498d577cfea
Autor:
Serena Di Cosimo, José Manuel Pérez-García, Meritxell Bellet, Florence Dalenc, Miguel J. Gil Gil, Manuel Ruiz-Borrego, Joaquín Gavilá, Elena Aguirre, Peter Schmid, Frederik Marmé, Joseph Gligorov, Andreas Schneeweiss, Joan Albanell, Pilar Zamora, Duncan Wheatley, Eduardo Martínez de Dueñas, Kepa Amillano, Eileen Shimizu, Miguel Sampayo-Cordero, Javier Cortés, Antonio Llombart-Cussac
Publikováno v:
Breast, Vol 76, Iss , Pp 103761- (2024)
Background: The capsule formulation of CDK4/6 inhibitor palbociclib has reduced solubility at gastric pH > 4.5 and may have decreased activity when used with proton-pump inhibitors (PPI). Herein, we report the effect of PPI on palbociclib capsule act
Externí odkaz:
https://doaj.org/article/d3b96315025744e9a531e42906d8d57a
Autor:
Alberto López-de la Rosa, Cecilia Díez-Montero, Elena Martínez-Plaza, Alberto López-Miguel, Miguel J. Maldonado
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 3, Pp 819-830 (2024)
Abstract Introduction Characterizing lens thickness (LT) in patients with cataracts is important for better understanding the lens aging process and for designing new intraocular lens power formulas. This study aimed to analyze the influence of commo
Externí odkaz:
https://doaj.org/article/7007e4ec9ce14c9ba042c3f2025156ef
Autor:
Eva Dopico, Marta Vila, David Tabernero, Josep Gregori, Ariadna Rando-Segura, Beatriz Pacín-Ruíz, Laura Guerrero, Itziar Ubillos, Miguel J. Martínez, Josep Costa, Josep Quer, Javier Pérez-Garreta, Alejandra González-Sánchez, Andrés Antón, Tomás Pumarola, Mar Riveiro-Barciela, Roser Ferrer-Costa, Maria Buti, Francisco Rodríguez-Frías, Maria Francesca Cortese
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5481 (2024)
Our aim was to develop an accurate, highly sensitive method for HBV genotype determination and detection of genotype mixtures. We examined the preS and 5′ end of the HBV X gene (5X) regions of the HBV genome using next-generation sequencing (NGS).
Externí odkaz:
https://doaj.org/article/8cc63ff3ff9e4ff8b59fb7dfc6670716
Autor:
Liina Nagirnaja, Alexandra M. Lopes, Wu-Lin Charng, Brian Miller, Rytis Stakaitis, Ieva Golubickaite, Alexandra Stendahl, Tianpengcheng Luan, Corinna Friedrich, Eisa Mahyari, Eloise Fadial, Laura Kasak, Katinka Vigh-Conrad, Manon S. Oud, Miguel J. Xavier, Samuel R. Cheers, Emma R. James, Jingtao Guo, Timothy G. Jenkins, Antoni Riera-Escamilla, Alberto Barros, Filipa Carvalho, Susana Fernandes, João Gonçalves, Christina A. Gurnett, Niels Jørgensen, Davor Jezek, Emily S. Jungheim, Sabine Kliesch, Robert I. McLachlan, Kenan R. Omurtag, Adrian Pilatz, Jay I. Sandlow, James Smith, Michael L. Eisenberg, James M. Hotaling, Keith A. Jarvi, Margus Punab, Ewa Rajpert-De Meyts, Douglas T. Carrell, Csilla Krausz, Maris Laan, Moira K. O’Bryan, Peter N. Schlegel, Frank Tüttelmann, Joris A. Veltman, Kristian Almstrup, Kenneth I. Aston, Donald F. Conrad
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The GEMINI consortium sequenced 1,000 cases of idiopathic male infertility and identified a plausible Mendelian cause in 20% of cases. The infertility genes can be grouped by expression pattern, facilitating their interpretation and follow-up.
Externí odkaz:
https://doaj.org/article/d33757f275f346459883626f17daf68f
Autor:
Mario Alberto Dantas L. da Costa, Nilson Soares P. de Mendonça, Miguel J. Froimtchuk, Sérgio E. Allan
Publikováno v:
Revista Brasileira de Cancerologia, Vol 32, Iss 1 (2023)
A osteoartropatia hipertrófica tem sido mais freqüentemente associada a câncer de pulmão. Raramente tem sido relacionada a doença metastática pulmonar, especialmente em osteossarcomas, sarcomas de partes moles, tumores do nasofaringe e uterinos
Externí odkaz:
https://doaj.org/article/6096e77179d445ddadcbf19c61fbae3c
Publikováno v:
Revista Brasileira de Cancerologia, Vol 34, Iss 2/3 (2023)
Entre agosto/83 e dezembro/85, oitenta e três pacientes portadores de câncer de mama avançado e resistente a múltiplos agentes quimioterápicos foram tratados com Mitomicina C 10mg/m2 iv 6/6 semanas e Vimblastina 6mg/m2 iv 3/3 semanas. Setenta e
Externí odkaz:
https://doaj.org/article/915d70c1dc7a4ba9b57df098164f0eb9
Autor:
Miguel J. Divo, José M. Marin, Ciro Casanova, Carlos Cabrera Lopez, Victor M. Pinto-Plata, Marta Marin-Oto, Francesca Polverino, Juan P. de-Torres, Dean Billheimer, Bartolome R. Celli, The BODE Collaborative Group
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Rationale and objective Patients with chronic obstructive pulmonary disease (COPD), usually diagnosed after the 6th decade, frequently suffer from comorbidities. Whether COPD patients 50 years or younger (Young COPD) have similar comorbiditi
Externí odkaz:
https://doaj.org/article/b2b6ecb0006c419f9337b0d9af77b7d5
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-7 (2022)
Probing the population of the cyanobacterium Synechococcus in an oligotrophic water column habitat at increasing depths reveals that light-harvesting quantum efficiency increases with depth.
Externí odkaz:
https://doaj.org/article/b251d510d43e415abe388a9f84a2f187
Publikováno v:
Selecciones Matemáticas, Vol 9, Iss 01, Pp 34-43 (2022)
This article presents a rigorous review of the conformable fractional derivative given by J. E. Napoles in [11], studying its classical properties, as a differential operator. Likewise, applications are given to Physics, specifically to the free fall
Externí odkaz:
https://doaj.org/article/16ba8ad521424b238f13940dfd45e8af