Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Miguel Garcia Castro"'
Autor:
Rafael Contreras-Cáceres, H. A. Pérez-Ramírez, Arturo Moncho-Jordá, Francisco Sarabia, Miguel Garcia‐Castro, Gerardo Odriozola, Alicia Germán-Bellod, Juan Manuel López-Romero, Matej Kanduč, Ana Belén Jódar-Reyes
Publikováno v:
ACS Nano. 14:15227-15240
We study the nonequilibrium diffusive release of electroneutral molecular cargo encapsulated inside hollow hydrogel nanoparticles. We propose a theoretical model that includes osmotic, steric, and short-range polymer-cargo attractions to determine th
Publikováno v:
European Journal of Organic Chemistry. 2017:5660-5665
A facile access to enantiomerically pure derivatives of α-hydroxy-β-amino acids bearing a quaternary center and trifluoromethylated tertiary alcohols which represent highly important building blocks to therapeutically relevant small molecules, was
Publikováno v:
Angewandte Chemie. 128:7712-7732
Die Gerustdiversitat ist ein entscheidendes Merkmal von Verbindungskollektionen, das einen grosen Einfluss auf deren Erfolg beim biologischen Screening hat. Die Synthese hochkomplexer und verschiedenartiger Geruste, die beispielsweise auf Naturstoffe
Publikováno v:
RSC Advances. 6:56537-56543
The zwitterionic 1,3-dipoles generated by the addition of a bifunctional L-isoleucine derived N-acylaminophosphine to allenic esters as well as ketones were successfully trapped with isatin derived ketimines in a [3 + 2]-annulation reaction to delive
Autor:
M. S. Pino‐Gonzalez, Cristina García-Ruiz, Miguel Garcia‐Castro, Carlos Vivar-García, Samy Chammaa, Antonio Sánchez-Ruiz, Francisco Sarabia
Publikováno v:
European Journal of Organic Chemistry. 2014:3847-3867
A new class of chiral sulfonium salts, derived from L- and D-methionine, has been designed and successfully employed in our laboratories for the diastereoselective synthesis of glycidic amides. The epoxy amides obtained were converted cleanly into 1,
Publikováno v:
Asian Journal of Organic Chemistry. 2:646-649
Publikováno v:
ChemInform. 47
Catalytic addition of chiral phosphine, that is, (R)- or (S)-SITCP, to an α-substituted allene ester generated a zwitterionic dipole. Under optimized reaction conditions, this dipole could engage isatine-derived N-Boc-ketimines in a novel mode of [3
Publikováno v:
ChemInform. 47
affording a wide range of dihydropyrrolyl spirooxindoles with excellent enantioselectivities
Publikováno v:
ChemInform. 47
Scaffold diversity is a crucial feature of compound collections that has a huge impact on their success in biological screenings. The synthesis of highly complex and diverse scaffolds, which could be based on natural products, for example, is an ardu
Autor:
Francisca Martín-Gálvez, José F. Tejón-Blanco, Samy Chammaa, Miguel Garcia‐Castro, Francisco Sarabia, Antonio Sánchez-Ruiz
Publikováno v:
The Journal of Organic Chemistry. 73:8979-8986
A new approach to the stereoselective synthesis of polypropionate-type frameworks is reported utilizing reactions of amide-stabilized sulfur ylides with chiral aldehydes. To establish a new strategy for macrolide fragment synthesis, the stereoselecti