Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Miguel Garcia‐Castro"'
Autor:
Rafael Contreras-Cáceres, H. A. Pérez-Ramírez, Arturo Moncho-Jordá, Francisco Sarabia, Miguel Garcia‐Castro, Gerardo Odriozola, Alicia Germán-Bellod, Juan Manuel López-Romero, Matej Kanduč, Ana Belén Jódar-Reyes
Publikováno v:
ACS Nano. 14:15227-15240
We study the nonequilibrium diffusive release of electroneutral molecular cargo encapsulated inside hollow hydrogel nanoparticles. We propose a theoretical model that includes osmotic, steric, and short-range polymer-cargo attractions to determine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feadec5f44a43935c2ceaa0719ca72cb
https://doi.org/10.1021/acsnano.0c05480
https://doi.org/10.1021/acsnano.0c05480
Publikováno v:
European Journal of Organic Chemistry. 2017:5660-5665
A facile access to enantiomerically pure derivatives of α-hydroxy-β-amino acids bearing a quaternary center and trifluoromethylated tertiary alcohols which represent highly important building blocks to therapeutically relevant small molecules, was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1092689ce450a859fff3f4ebe22a1d91
https://doi.org/10.1002/ejoc.201701148
https://doi.org/10.1002/ejoc.201701148
Publikováno v:
Angewandte Chemie. 128:7712-7732
Die Gerustdiversitat ist ein entscheidendes Merkmal von Verbindungskollektionen, das einen grosen Einfluss auf deren Erfolg beim biologischen Screening hat. Die Synthese hochkomplexer und verschiedenartiger Geruste, die beispielsweise auf Naturstoffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39199c577b4f447a797275f19e3e0fe
https://doi.org/10.1002/ange.201508818
https://doi.org/10.1002/ange.201508818
Publikováno v:
RSC Advances. 6:56537-56543
The zwitterionic 1,3-dipoles generated by the addition of a bifunctional L-isoleucine derived N-acylaminophosphine to allenic esters as well as ketones were successfully trapped with isatin derived ketimines in a [3 + 2]-annulation reaction to delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d5eb6ca0301ed6bf4eb0fcec04f1f79
https://doi.org/10.1039/c6ra12387b
https://doi.org/10.1039/c6ra12387b
Autor:
M. S. Pino‐Gonzalez, Cristina García-Ruiz, Miguel Garcia‐Castro, Carlos Vivar-García, Samy Chammaa, Antonio Sánchez-Ruiz, Francisco Sarabia
Publikováno v:
European Journal of Organic Chemistry. 2014:3847-3867
A new class of chiral sulfonium salts, derived from L- and D-methionine, has been designed and successfully employed in our laboratories for the diastereoselective synthesis of glycidic amides. The epoxy amides obtained were converted cleanly into 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de727da3f0b0b4693f04cd643dc297d5
https://doi.org/10.1002/ejoc.201402221
https://doi.org/10.1002/ejoc.201402221
Publikováno v:
Asian Journal of Organic Chemistry. 2:646-649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea59c073b5546c08ed49fb7c40b63331
https://doi.org/10.1002/ajoc.201300120
https://doi.org/10.1002/ajoc.201300120
Publikováno v:
ChemInform. 47
Catalytic addition of chiral phosphine, that is, (R)- or (S)-SITCP, to an α-substituted allene ester generated a zwitterionic dipole. Under optimized reaction conditions, this dipole could engage isatine-derived N-Boc-ketimines in a novel mode of [3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432f8efbb3fb814b8227065bed1cc67f
https://doi.org/10.1002/chin.201650081
https://doi.org/10.1002/chin.201650081
Publikováno v:
ChemInform. 47
affording a wide range of dihydropyrrolyl spirooxindoles with excellent enantioselectivities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8ac1da04bc2bf09343e5d38497c623
https://doi.org/10.1002/chin.201643099
https://doi.org/10.1002/chin.201643099
Publikováno v:
ChemInform. 47
Scaffold diversity is a crucial feature of compound collections that has a huge impact on their success in biological screenings. The synthesis of highly complex and diverse scaffolds, which could be based on natural products, for example, is an ardu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bb332bcb91578d00edac547219b78ad
https://doi.org/10.1002/chin.201635174
https://doi.org/10.1002/chin.201635174
Autor:
Francisca Martín-Gálvez, José F. Tejón-Blanco, Samy Chammaa, Miguel Garcia‐Castro, Francisco Sarabia, Antonio Sánchez-Ruiz
Publikováno v:
The Journal of Organic Chemistry. 73:8979-8986
A new approach to the stereoselective synthesis of polypropionate-type frameworks is reported utilizing reactions of amide-stabilized sulfur ylides with chiral aldehydes. To establish a new strategy for macrolide fragment synthesis, the stereoselecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0d22456cc7f413aff7d20c9e383689
https://doi.org/10.1021/jo801728s
https://doi.org/10.1021/jo801728s