Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Miguel Foronda"'
Autor:
Miguel Foronda, Yusuke Tarumoto, Emma M Schatoff, Benjamin I Leach, Bianca J Diaz, Jill Zimmerman, Sukanya Goswami, Michael Shusterman, Christopher R Vakoc, Lukas E Dow
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226645 (2019)
Tankyrase (TNKS) 1/2 are positive regulators of WNT signaling by controlling the activity of the ß-catenin destruction complex. TNKS inhibitors provide an opportunity to suppress hyperactive WNT signaling in tumors, however, they have shown limited
Externí odkaz:
https://doaj.org/article/fe38eb09ce16417485ff4b1070b18de3
Autor:
Miguel Foronda, Lucia Morgado-Palacin, Gonzalo Gómez-López, Orlando Domínguez, David G. Pisano, Maria A. Blasco
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 21-24 (2015)
Adult stem cells (ASCs) reside in specific niches in a quiescent state in adult mammals. Upon specific cues they become activated and respond by self-renewing and differentiating into newly generated specialised cells that ensure appropriate tissue f
Externí odkaz:
https://doaj.org/article/1d95d3dfa3fa466fa89a6e75092f08b4
Autor:
Miguel Foronda, Paula Martínez, Stefan Schoeftner, Gonzalo Gómez-López, Ralph Schneider, Juana M. Flores, David G. Pisano, Maria A. Blasco
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 487-500 (2014)
Sox4 expression is restricted in mammals to embryonic structures and some adult tissues, such as lymphoid organs, pancreas, intestine, and skin. During embryogenesis, Sox4 regulates mesenchymal and neural progenitor survival, as well as lymphocyte an
Externí odkaz:
https://doaj.org/article/6a1efdbee50f4598af9c1085606d9d62
Autor:
Tania-Marisa Freitas-Simoes, Montserrat Cofán, Maria A. Blasco, Nora Soberón, Miguel Foronda, Mercè Serra-Mir, Irene Roth, Cinta Valls-Pedret, Mónica Doménech, Elena Ponferrada-Ariza, Carlos Calvo, Sujatha Rajaram, Joan Sabaté, Emilio Ros, Aleix Sala-Vila
Publikováno v:
Nutrients, Vol 10, Iss 12, p 1907 (2018)
Randomized controlled trials on diet and shortening of leukocyte telomere length (LTL) mostly focus on marine-derived n-3 polyunsaturated fatty acids (PUFA). Walnuts are a sustainable source of n-3 PUFA. We investigated whether inclusion of walnuts (
Externí odkaz:
https://doaj.org/article/22766dfc97e8401d96176b1ab9ca9495
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 732-737 (2012)
Aberrantly short telomeres result in decreased longevity in both humans and mice with defective telomere maintenance. Normal populations of humans and mice present high interindividual variation in telomere length, but it is unknown whether this is a
Externí odkaz:
https://doaj.org/article/5e59b0ec9fe14382beeb680b7e8830b3
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53760 (2013)
Caloric restriction (CR), a reduction of food intake while avoiding malnutrition, can delay the onset of cancer and age-related diseases in several species, including mice. In addition, depending of the genetic background, CR can also increase or dec
Externí odkaz:
https://doaj.org/article/8f7fba8dd6f641bfa6c085b5d64d3f8d
Autor:
Raffaele Strippoli, Jesús Loureiro, Vanessa Moreno, Ignacio Benedicto, María Luisa Pérez Lozano, Olga Barreiro, Teijo Pellinen, Susana Minguet, Miguel Foronda, Maria Teresa Osteso, Enrique Calvo, Jesús Vázquez, Manuel López Cabrera, Miguel Angel del Pozo
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 357-357 (2015)
Externí odkaz:
https://doaj.org/article/a3a2916583224270974b1bee55e89501
Autor:
Lukas E. Dow, Bianca J. Diaz, Alyna Katti, Benjamin I. Leach, Michael Shusterman, Miguel Foronda, Maria Paz Zafra, Sukanya Goswami, Emma M. Schatoff
The majority of colorectal cancers show hyperactivated WNT signaling due to inactivating mutations in the adenomatous polyposis coli (APC) tumor suppressor. Genetically restoring APC suppresses WNT and induces rapid and sustained tumor regression, im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5abd6f8d58ad9ae339c892d786ec2b32
https://doi.org/10.1158/2159-8290.c.6547946.v1
https://doi.org/10.1158/2159-8290.c.6547946.v1
Autor:
Lukas E. Dow, Bianca J. Diaz, Alyna Katti, Benjamin I. Leach, Michael Shusterman, Miguel Foronda, Maria Paz Zafra, Sukanya Goswami, Emma M. Schatoff
Results of statistical tests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0b9ba1071f5f57dad2b6c86dd09d0c
https://doi.org/10.1158/2159-8290.22535804
https://doi.org/10.1158/2159-8290.22535804
Autor:
Lukas E. Dow, Bianca J. Diaz, Alyna Katti, Benjamin I. Leach, Michael Shusterman, Miguel Foronda, Maria Paz Zafra, Sukanya Goswami, Emma M. Schatoff
Oligonucleotide sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a1c48b09351fa1c886882d1a7c571d
https://doi.org/10.1158/2159-8290.22535807
https://doi.org/10.1158/2159-8290.22535807