Výsledky vyhledávání - "Miguel E. Ortiz"

Akademický článek

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

Autor: Miguel E. Ortiz, Andrew Thurman, Alejandro A. Pezzulo, Mariah R. Leidinger, Julia A. Klesney-Tait, Philip H. Karp, Ping Tan, Christine Wohlford-Lenane, Paul B. McCray, Jr., David K. Meyerholz

Publikováno v: EBioMedicine, Vol 60, Iss , Pp 102976- (2020)

Background: Zoonotically transmitted coronaviruses are responsible for three disease outbreaks since 2002, including the current COVID-19 pandemic, caused by SARS-CoV-2. Its efficient transmission and range of disease severity raise questions regardi

Externí odkaz: https://doaj.org/article/aca39e31195e472f99e4e21970a117e7

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Akademický článek

Lack of airway submucosal glands impairs respiratory host defenses

Publikováno v: eLife, Vol 9 (2020)

Submucosal glands (SMGs) are a prominent structure that lines human cartilaginous airways. Although it has been assumed that SMGs contribute to respiratory defense, that hypothesis has gone without a direct test. Therefore, we studied pigs, which hav

Externí odkaz: https://doaj.org/article/de4e52b4b350483bb95240e3006ac61e

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Impact of Atrial Fibrillation on In-Hospital Mortality and Thromboembolic Complications after Left Ventricular Assist Device Implantation

Autor: Stephen J. Greene, Vanessa Blumer, Veraprapas Kittipibul, Emer Joyce, Gabriel A. Hernandez, Sandra Chaparro, Miguel E Ortiz Bezara, Marat Fudim

Publikováno v: Journal of Cardiovascular Translational Research. 14:120-124

The association between atrial fibrillation (AF) and thromboembolic (TE) complications in left ventricular assist device (LVAD) recipients is controversial, and there is paucity of large-scale data evaluating the impact of AF on early outcomes after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::550caab598fccfdfc424a80a31b5afd8
https://doi.org/10.1007/s12265-020-09968-5

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Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

Publikováno v: Nature
Digital.CSIC. Repositorio Institucional del CSIC
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Coronavirus disease 2019 (COVID-19) is especially severe in aged populations1. Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are highly effective, but vaccine efficacy is partly compromised by the emergence of SARS-CoV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcd2efc0e805bd6c7c60820d81c8126

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Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19

Autor: Klaus Klumpp, Miguel E Ortiz Bezara, Jian Zheng, Fred Aswad, Alejandro A. Pezzulo, Peter J Szachowicz, Kevin Wilhelmsen, Kristen Fortney, Lok Yin Roy Wong, Makoto Murakami, David K. Meyerholz, Paul B. McCray, Kun Li, Stanley Perlman, Justin Rebo, Shut Narumiya, Nicholas J. Schnicker

Publikováno v: bioRxiv
article-version (status) pre
article-version (number) 1

Coronavirus disease 2019 (COVID-19) is especially severe in aged populations1. Resolution of the COVID-19 pandemic has been advanced by the recent development of SARS-CoV-2 vaccines, but vaccine efficacy is partly compromised by the recent emergence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49e7ae9f6093ec50c6787b17681bcf6
http://europepmc.org/articles/PMC8077574

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Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19

Publikováno v: The Journal of Immunology. 208:125.05-125.05

Coronavirus disease 2019 (COVID-19) is especially severe in aged populations. Resolution of the COVID-19 pandemic has been advanced by the recent development of SARS-CoV-2 vaccines, but vaccine efficacy is partly compromised by the recent emergence o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8469c7c3dbcb9665c53c1b87415be8df
https://doi.org/10.4049/jimmunol.208.supp.125.05

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K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia

Autor: David K. Meyerholz, Abhishek Kumar Verma, Stanley Perlman, Miguel E Ortiz Bezara, Paul B. McCray, Jian Zheng, Kun Li, Michael C. Kundson, Mariah R. Leidinger, Lok Yin Roy Wong, Christine L. Wohlford-Lenane

Publikováno v: Nature
bioRxiv

The ongoing COVID-19 pandemic is associated with substantial morbidity and mortality. While much has been learned in the first months of the pandemic, many features of COVID-19 pathogenesis remain to be determined. For example, anosmia is a common pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c97be3166439153cb8085c3afba1340
https://pubmed.ncbi.nlm.nih.gov/33166988

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