Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Miguel E. Moreno-García"'
Autor:
Cristina Trejo-Solís, Guadalupe Palencia, Sergio Zuñiga, Andrea Rodríguez-Ropon, Laura Osorio-Rico, Sanchez Torres Luvia, Isabel Gracia-Mora, Lucrecia Marquez-Rosado, Aurora Sánchez, Miguel E. Moreno-García, Arturo Cruz, María Elena Bravo-Gómez, Lena Ruiz-Ramírez, Sara Rodríquez-Enriquez, Julio Sotelo
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 6, Pp 563-574 (2005)
In this work, we investigated the effects of Casiopeina Il-gly (Cas ILgly)—a new copper compound exhibiting antineoplastic activity—on glioma C6 cells under both in vitro and in vivo conditions, as an approach to identify potential therapeutic ag
Externí odkaz:
https://doaj.org/article/b0b5eced13dd4d94bd6121342239dcb4
Autor:
Tiago Carvalheiro, Wioleta Marut, M. Inês Pascoal Ramos, Samuel García, Devan Fleury, Alsya J. Affandi, Aniek S. Meijers, Barbara Giovannone, Ralph G. Tieland, Eline Elshof, Andrea Ottria, Marta Cossu, Matthew L. Meizlish, Tineke Veenendaal, Meera Ramanujam, Miguel E. Moreno-García, Judith Klumperman, Nalan Liv, Timothy R.D.J. Radstake, Linde Meyaard
SummaryTissue repair is disturbed in fibrotic diseases like systemic sclerosis (SSc), where the deposition of large amounts of extracellular matrix components such as collagen interferes with organ function. LAIR-1 is an inhibitory collagen receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9be816d427ea40a4f319d28194692d26
https://doi.org/10.1101/2021.12.07.471103
https://doi.org/10.1101/2021.12.07.471103
Autor:
Marilyn R. Kehry, Troy D. Randall, Miguel E. Moreno-García, Kim Kusser, David J. Rawlings, Guixiu Shi, Shirly Becker-Herman, Kelly L. Hudkins, Melvin I. Simon, Denny Liggitt, Michael Tighe, Robert Dunn, Ann Marshak-Rothstein, Betty Mousseau, Ravi S. Misra, Charles E. Alpers, Frances E. Lund, Thi Sau Migone, Anil Thankappan
Publikováno v:
The Journal of Experimental Medicine
Survival of mature B cells is regulated by B cell receptor and BAFFR-dependent signals. We show that B cells from mice lacking the Gαq subunit of trimeric G proteins (Gnaq−/− mice) have an intrinsic survival advantage over normal B cells, even i
Autor:
Miguel E. Moreno-García, Karen Sommer, Tomohiro Kurosaki, Hisaaki Shinohara, Ashok D. Bandaranayake, David J. Rawlings
Publikováno v:
Molecular and Cellular Biology. 30:922-934
The adaptor protein CARMA1 is required for antigen receptor-triggered activation of IKK and JNK in lymphocytes. Once activated, the events that subsequently turn off the CARMA1 signalosome are unknown. In this study, we found that antigen receptor-ac
Autor:
Clayton Sontheimer, David J. Rawlings, Miguel E. Moreno-García, Claudia Haftmann, Karen Sommer, Sarah F. Andrews
Publikováno v:
The Journal of Immunology. 183:7362-7370
Phosphorylation of CARMA1 is a crucial event initiating the assembly of IκB kinase and JNK signaling complexes downstream of activated Ag receptors. We previously mapped three protein kinase C (PKC) target sites in murine CARMA1 in vitro, and demons
Publikováno v:
European Journal of Immunology. 37:358-367
It is becoming increasingly clear that the regulation of proliferation and differentiation of B cells to plasma cells involves the integration of a variety of intracellular signals provided by receptors of both the adaptive and innate immune system.
Autor:
Santiago Partida-Sanchez, Francis Schuber, Leopoldo Santos-Argumedo, Miguel E. Moreno-García, Héctor Romero-Ramírez, Hélène Muller-Steffner, Melissa Makris, Frances E. Lund, Norman J. Oppenheimer
Publikováno v:
International Immunology. 18:1029-1042
Cross-linking of CD38 on hematopoietic cells induces activation, proliferation and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an
Autor:
Andrea Rodríguez-Ropon, Sara Rodríquez-Enriquez, Arturo Cruz, Lucrecia Marquez-Rosado, Sergio Zuñiga, Julio Sotelo, Guadalupe Palencia, Miguel E. Moreno-García, Laura Osorio-Rico, Sanchez Torres Luvia, Aurora Sánchez, María Elena Bravo-Gómez, Isabel Gracia-Mora, Lena Ruiz-Ramirez, Cristina Trejo-Solís
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 6, Pp 563-574 (2005)
In this work, we investigated the effects of Casiopeina Il-gly (Cas ILgly)—a new copper compound exhibiting antineoplastic activity—on glioma C6 cells under both in vitro and in vivo conditions, as an approach to identify potential therapeutic ag
Publikováno v:
Molecular Immunology. 42:703-711
CD38 has been widely characterized both as an ecto-enzyme and as a receptor. As an enzyme, CD38 catalyzes the conversion of NAD+ and NADP to several metabolites including cADPR and NAADP, which mediate Ca2+ release from separate intracellular stores,
Autor:
Alejandro Zentella, Lucia N. López-Bojórques, Miguel E. Moreno-García, Lisa A. Humphries, Leopoldo Santos-Argumedo, David J. Rawlings
Publikováno v:
The Journal of Immunology. 174:2687-2695
The CD38 cell surface receptor is a potent activator for splenic, B lymphocytes. The molecular mechanisms regulating this response, however, remain incompletely characterized. Activation of the nonreceptor tyrosine kinase, Btk, is essential for CD38