Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Miguel E Moreno-Garcia"'
Autor:
Della White, Alexandra Cote-Martin, Marina Bleck, Nicole Garaffa, Abdulsalam Shaaban, Helen Wu, Dongmei Liu, David Young, Justin Scheer, Ivo C. Lorenz, Andrew Nixon, Jay S. Fine, Fergus R. Byrne, M.Lamine Mbow, Miguel E. Moreno-Garcia
Publikováno v:
Molecular Immunology. 156:31-38
Publikováno v:
The Journal of Immunology. 182:33.31-33.31
In lymphocytes, the antigen receptor utilizes a unique scaffolding molecule, CARMA1, to organize an oligomerization cascade that ultimately activates NF-kappaB. Activation of CARMA1 is characterized by conformational changes that expose binding sites
Autor:
Blythe D Sather, Svitlana V Mikhalap, Miguel E Moreno-Garcia, Karen Sommer, Larysa M Shlapatska, Svetlana P Sidorenko, David J Rawlings
Publikováno v:
The Journal of Immunology. 182:88.19-88.19
Development of therapies for diffuse large B-cell lymphomas (DLBCL) requires a precise knowledge of signaling aberrations essential for tumor development. In normal B cells, the B cell receptor (BCR) initiates intracellular signals crucial for the su