Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Miguel Chillon"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10025 (2021)
PolyPurine Reverse Hoogsteen Hairpins (PPRHs) are gene-silencing DNA-oligonucleotides developed in our laboratory that are formed by two antiparallel polypurine mirror repeat domains bound intramolecularly by Hoogsteen bonds. The aim of this work was
Externí odkaz:
https://doaj.org/article/1693b5ea8a6046388319c379fd45f27e
Autor:
Anna Massó, Angela Sánchez, Lydia Gimenez-Llort, Jose Miguel Lizcano, Manuel Cañete, Belen García, Virginia Torres-Lista, Meritxell Puig, Assumpció Bosch, Miguel Chillon
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143623 (2015)
The Klotho protein is a β-glucuronidase, and its overexpression is associated with life extension. Its mechanism of action is not fully understood, although it has been recently reported that αKlotho improves synaptic and cognitive functions, and i
Externí odkaz:
https://doaj.org/article/608ffecc3263482098786e5307450b34
Autor:
Estel Gil, Assumpcio Bosch, David Lampe, Jose M Lizcano, Jose C Perales, Olivier Danos, Miguel Chillon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73227 (2013)
DNA transposons are mobile elements with the ability to mobilize and transport genetic information between different chromosomal loci. Unfortunately, most transposons copies are currently inactivated, little is known about mariner elements in humans
Externí odkaz:
https://doaj.org/article/89aa1b2975ed46929838190c38e31688
Autor:
Stefania Piersanti, Letizia Astrologo, Valerio Licursi, Rossella Costa, Enrica Roncaglia, Aurelie Gennetier, Sandy Ibanes, Miguel Chillon, Rodolfo Negri, Enrico Tagliafico, Eric J Kremer, Isabella Saggio
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69808 (2013)
Several studies have demonstrated the potential for vector-mediated gene transfer to the brain. Helper-dependent (HD) human (HAd) and canine (CAV-2) adenovirus, and VSV-G-pseudotyped self-inactivating HIV-1 vectors (LV) effectively transduce human br
Externí odkaz:
https://doaj.org/article/39c5d6b4005843b8b4176af798979f6a
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42073 (2012)
The human adenovirus 40 (Ad40) is a promising tool for gene therapy of intestinal diseases. Since the production of Ad40 in vitro is extremely inefficient, chimeric Adenovirus 5/40S vectors carrying the Ad40 short fiber on the Ad5 capsid have been de
Externí odkaz:
https://doaj.org/article/85e73b1e1afc424f8a910e09ad795542
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19564 (2011)
We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain. These novel helper viruses have a significantly delayed viral life cy
Externí odkaz:
https://doaj.org/article/face692722f548ef84b28f4191e0ef99
Publikováno v:
Scientia
International Journal of Molecular Sciences, Vol 22, Iss 10025, p 10025 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 22, Iss 10025, p 10025 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
Dipòsit Digital de la UB
Universidad de Barcelona
Adenovirus; Terapia contra el cáncer; Vectores virales Adenovirus; Cancer therapy; Viral vectors Adenovirus; Teràpia contra el càncer; Vectors virals PolyPurine Reverse Hoogsteen Hairpins (PPRHs) are gene-silencing DNA-oligonucleotides developed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5de1d87a83147b4b35340c2678246c
https://hdl.handle.net/11351/7395
https://hdl.handle.net/11351/7395
Autor:
Armando Almeida, Rita C. Assunção-Silva, Sandra Barata-Antunes, Assumpcio Bosch, Nicholas M. Boulis, Alice Braga, Bing Chen, Miguel Chillon, Jorge E. Collazos-Castro, João Cortinhas, Jianwu Dai, Ignacio Delgado-Martínez, Jaume del Valle, Madalena Esteves, Razan Faraj, Thais Federici, Michael G. Fehlings, Aline M. Fernandes, Miguel Gago, Guillermo García-Alías, Julian L. Gendreau, Eduardo D. Gomes, Alex Greven, Laureen D. Hachem, Regan Hamel, R.M. Ichiyama, Pavla Jendelová, Kristýna Kárová, Kristýna Kekulová, R.W.P. Kissane, Zuzana Kočí, Šárka Kubinová, Hugo Leite-Almeida, Mariah Lelos, Zhijia Liang, Rui Lima, Sara Monteiro Lopes, Alvaro Machado, Cláudia R. Marques, Susana Monteiro, Pedro M.D. Moreno, Xavier Navarro, Itse Onuwaje, Ana P. Pêgo, Inês M. Pereira, Luís Pereira de Almeida, Luca Peruzzotti-Jametti, James B. Phillips, Stefano Pluchino, Sofia Rocha, Nataliya Romanyuk, Carola Rutigliani, António J. Salgado, Nadine Correia Santos, Nuno A. Silva, Jayden A. Smith, Barbora Svobodová, Fábio G. Teixeira, Andreia Teixeira-Castro, Pavlos Texakalidis, Muhibullah S. Tora, Lucia Machova Urdzíková, Zhifeng Xiao, Bryan Yu, Yannan Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33877bbd26bf36a71c983a078a4a0fa
https://doi.org/10.1016/b978-0-12-818084-6.00024-6
https://doi.org/10.1016/b978-0-12-818084-6.00024-6
Autor:
Joan Roig-Soriano, Cristina Sánchez-de-Diego, Jon Esandi-Jauregui, Sergi Verdés, Carmela R. Abraham, Assumpció Bosch, Francesc Ventura, Miguel Chillón
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The aging-protective gene α-Klotho (KL) produces two main transcripts. The full-length mRNA generates a transmembrane protein that after proteolytic ectodomain shedding can be detected in serum as processed Klotho (p-KL), and a shorter tran
Externí odkaz:
https://doaj.org/article/6d0e213469a84004ae0d9ef85a56bf58
Autor:
Miguel, Chillon, Ramon, Alemany
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 737
The most efficient system to introduce genes of interest within the adenovirus genome is by homologous recombination in microorganisms. In this chapter, the most popular procedures are described: two for homologous recombination in Escherichia coli,