Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Miguel Carracedo"'
Autor:
Hernán González‐King, Patricia G. Rodrigues, Tamsin Albery, Benyapa Tangruksa, Ramya Gurrapu, Andreia M. Silva, Gentian Musa, Dominika Kardasz, Kai Liu, Bengt Kull, Karin Åvall, Katarina Rydén‐Markinhuhta, Tania Incitti, Nitin Sharma, Cecilia Graneli, Hadi Valadi, Kasparas Petkevicius, Miguel Carracedo, Sandra Tejedor, Alena Ivanova, Sepideh Heydarkhan‐Hagvall, Phillipe Menasché, Jane Synnergren, Niek Dekker, Qing‐Dong Wang, Karin Jennbacken
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Small extracellular vesicles (sEV) derived from various cell sources have been demonstrated to enhance cardiac function in preclinical models of myocardial infarction (MI). The aim of this study was to compare different sources of sEV for ca
Externí odkaz:
https://doaj.org/article/c768354e5bb04d27b8a38ee892355c5b
Autor:
Miguel Carracedo, Elke Ericson, Rasmus Ågren, Anna Forslöw, Katja Madeyski-Bengtson, Anna Svensson, Rebecca Riddle, Jonas Christoffersson, Hernán González-King Garibotti, Bojana Lazovic, Ryan Hicks, Lisa Buvall, Alessia Fornoni, Peter J. Greasley, Mark Lal
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106830- (2023)
Summary: Apolipoprotein L1 (APOL1) high-risk genotypes are associated with increased risk of chronic kidney disease (CKD) in people of West African ancestry. Given the importance of endothelial cells (ECs) in CKD, we hypothesized that APOL1 high-risk
Externí odkaz:
https://doaj.org/article/e7b72c9152f540b5a5332bc61f411e47
Autor:
Miguel Carracedo, PhD, Leif Stenke, MD, PhD, Anders Franco-Cereceda, MD, PhD, Magnus Bäck, MD, PhD
Publikováno v:
JACC. CardioOncology, Vol 2, Iss 1, Pp 123-126 (2020)
Externí odkaz:
https://doaj.org/article/fe33173362164742a676788739188429
Autor:
Magnus Bäck, Tamas Aranyi, M. Leonor Cancela, Miguel Carracedo, Natércia Conceição, Georges Leftheriotis, Vicky Macrae, Ludovic Martin, Yvonne Nitschke, Andreas Pasch, Daniela Quaglino, Frank Rutsch, Catherine Shanahan, Victor Sorribas, Flora Szeri, Pedro Valdivielso, Olivier Vanakker, Hervé Kempf
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2019)
The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed light on the consequences of loss-of-function mutations for differe
Externí odkaz:
https://doaj.org/article/3fe708b1561b45f9ade871982d4502e6
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Intimal hyperplasia remains a significant clinical problem in for example coronary artery bypass graft failure. Since omega-3 fatty acids reduce intimal hyperplasia, we hypothesized that the G protein-coupled receptor ChemR23 for the omega-3-derived
Externí odkaz:
https://doaj.org/article/ccd94a484cb94dfdafdc78468710c639
Autor:
Glykeria Karadimou, Oscar Plunde, Sven-Christian Pawelzik, Miguel Carracedo, Per Eriksson, Anders Franco-Cereceda, Gabrielle Paulsson-Berne, Magnus Bäck
Publikováno v:
Cells, Vol 9, Iss 7, p 1710 (2020)
Calcific aortic valve stenosis (CAVS) is a common age-related disease characterized by active calcification of the leaflets of the aortic valve. How innate immune cells are involved in disease pathogenesis is not clear. In this study we investigate t
Externí odkaz:
https://doaj.org/article/7de088f5defc440a8f2610bbe3e235c5
Autor:
Gonzalo Artiach, Miguel Carracedo, Till Seime, Oscar Plunde, Andres Laguna-Fernandez, Ljubica Matic, Anders Franco-Cereceda, Magnus Bäck
Publikováno v:
Cells, Vol 9, Iss 3, p 684 (2020)
Aortic valve stenosis (AVS), a consequence of increased fibrosis and calcification of the aortic valve leaflets, causes progressive narrowing of the aortic valve. Proteoglycans, structural components of the aortic valve, accumulate in regions with fi
Externí odkaz:
https://doaj.org/article/91029a4bb91e4f62b6f906ae82b0168d
Autor:
Miguel Carracedo, Oscar Persson, Peter Saliba-Gustafsson, Gonzalo Artiach, Ewa Ehrenborg, Per Eriksson, Anders Franco-Cereceda, Magnus Bäck
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1486 (2019)
Autophagy serves as a cell survival mechanism which becomes dysregulated under pathological conditions and aging. Aortic valve thickening and calcification causing left ventricular outflow obstruction is known as calcific aortic valve stenosis (CAVS)
Externí odkaz:
https://doaj.org/article/189f4e600c0a40ada2a32adc0dd1ecb8
Autor:
Miguel Carracedo, Sven‐Christian Pawelzik, Gonzalo Artiach, Marianne G. Pouwer, Oscar Plunde, Peter Saliba‐Gustafsson, Ewa Ehrenborg, Per Eriksson, Elsbet Pieterman, Leif Stenke, Hans M. G. Princen, Anders Franco‐Cereceda, Magnus Bäck
Publikováno v:
British journal of pharmacology. 179(19)
Tyrosine kinase inhibitors (TKI) used to treat chronic myeloid leukaemia (CML) have been associated with cardiovascular side effects, including reports of calcific aortic valve stenosis. The aim of this study was to establish the effects of first and
Autor:
Hildur Arnardottir, Peter Sjövall, Miguel Carracedo, Oscar Plunde, Silke Thul, Magnus Bäck, Gonzalo Artiach, Anders Franco-Cereceda, Craig E. Wheelock, Andres Laguna-Fernandez
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Aortic valve stenosis (AVS), which is the most common valvular heart disease, causes a progressive narrowing of the aortic valve as a consequence of thickening and calcification
Background: Aortic valve stenosis (AVS), which is the most common valvular heart disease, causes a progressive narrowing of the aortic valve as a consequence of thickening and calcification