Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Miguel Cacho Teixeira"'
Autor:
Michiyo Okamoto, Keiko Nakano, Azusa Takahashi-Nakaguchi, Kaname Sasamoto, Masashi Yamaguchi, Miguel Cacho Teixeira, Hiroji Chibana
Publikováno v:
Journal of Fungi, Vol 9, Iss 2, p 240 (2023)
Mitochondrial dysfunction or morphological abnormalities in human pathogenic fungi are known to contribute to azole resistance; however, the underlying molecular mechanisms are unknown. In this study, we investigated the link between mitochondrial mo
Externí odkaz:
https://doaj.org/article/dfc649e4cb3e4deb91035884946e46a7
Autor:
Pedro Pais, Mónica Galocha, Romeu Viana, Mafalda Cavalheiro, Diana Pereira, Miguel Cacho Teixeira
Publikováno v:
Microbial Cell, Vol 6, Iss 3, Pp 142-159 (2019)
Infections by the pathogenic yeasts Candida albicans and Candida glabrata are among the most common fungal diseases. The success of these species as human pathogens is contingent on their ability to resist antifungal therapy and thrive within the hum
Externí odkaz:
https://doaj.org/article/af7d65d4d9f54ffb9a6cc0e2c5b48a05
Autor:
Sandra Godinho Silva, Patrícia Paula, José Paulo da Silva, Dalila Mil-Homens, Miguel Cacho Teixeira, Arsénio Mendes Fialho, Rodrigo Costa, Tina Keller-Costa
Publikováno v:
Marine Drugs, Vol 20, Iss 7, p 423 (2022)
Two novel natural products, the polyketide cuniculene and the peptide antibiotic aquimarin, were recently discovered from the marine bacterial genus Aquimarina. However, the diversity of the secondary metabolite biosynthetic gene clusters (SM-BGCs) i
Externí odkaz:
https://doaj.org/article/28d966a9ab094e6082942e338c527d96
Autor:
Sophie Klemm, Martina Baum, Haoyi Qiu, Zibin Nan, Mafalda Cavalheiro, Miguel Cacho Teixeira, Claire Tendero, Anna Gapeeva, Rainer Adelung, Etienne Dague, Mickaël Castelain, Cécile Formosa-Dague
Publikováno v:
Nanomaterials, Vol 11, Iss 2, p 271 (2021)
The attachment of bacteria and other microbes to natural and artificial surfaces leads to the development of biofilms, which can further cause nosocomial infections. Thus, an important field of research is the development of new materials capable of
Externí odkaz:
https://doaj.org/article/dbaed8c3b8e746079fae9c8320e8af39
Publikováno v:
Journal of Fungi, Vol 6, Iss 3, p 171 (2020)
Candida albicans is one of the most impactful fungal pathogens and the most common cause of invasive candidiasis, which is associated with very high mortality rates. With the rise in the frequency of multidrug-resistant clinical isolates, the identif
Externí odkaz:
https://doaj.org/article/b6a952791da24fa88f674e2ba1428a7b
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Candida species are fungal pathogens known for their ability to cause superficial and systemic infections in the human host. These pathogens are able to persist inside the host due to the development of pathogenicity and multidrug resistance traits,
Externí odkaz:
https://doaj.org/article/0cfabf4ba90b4000884df54e0ffa7b6c
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Transcription factors are key players in the control of the activation or repression of gene expression programs in response to environmental stimuli. The study of regulatory networks taking place in fungal pathogens is a promising research topic tha
Externí odkaz:
https://doaj.org/article/3c5bf79437be4fe3a0794dec3dc69f99
Autor:
Catarina eCosta, Jonathan eRibeiro, Isabel M Miranda, Ana Isabel Silva-Dias, Mafalda eCavalheiro, Sofia eCosta-de-Oliveira, Acácio Gonçalves Rodrigues, Miguel Cacho Teixeira
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
For years, antifungal drug resistance in Candida species has been associated to the expression of ATP-Binding Cassette (ABC) multidrug transporters. More recently, a few drug efflux pumps from the Drug:H+ Antiporter (DHA) family have also been shown
Externí odkaz:
https://doaj.org/article/71e9d37df4c2412bb04e8fa85e1cd4d5
Autor:
Catarina Costa, Andreia Ponte, Pedro Pais, Rui Santos, Mafalda Cavalheiro, Takashi Yaguchi, Hiroji Chibana, Miguel Cacho Teixeira
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135110 (2015)
5-Flucytosine is currently used as an antifungal drug in combination therapy, but fungal pathogens are rapidly able to develop resistance against this drug, compromising its therapeutic action. The understanding of the underlying resistance mechanism
Externí odkaz:
https://doaj.org/article/d12f3f49283749c695d333a2e431f482