HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content

Autor: Dedipya Yelamanchili, Baiba K. Gillard, Antonio M. Gotto, Jr., Miguel Caínzos Achirica, Khurram Nasir, Alan T. Remaley, Corina Rosales, Henry J. Pownall

Publikováno v: Journal of Lipid Research, Vol 66, Iss 1, Pp 100707- (2025)

High-density lipoprotein (HDL)-free cholesterol (FC) transfers to other lipoproteins and cells, the former by a spontaneous mechanism and the latter by both spontaneous and receptor-mediated mechanisms. Macrophages are an important cell type in all s

Externí odkaz: https://doaj.org/article/6d7cba0aea5d4f68b28b03eccc94afe4

Association of cardiovascular risk profile with healthcare expenditure and resource utilization in chronic obstructive pulmonary disease, with and without atherosclerotic cardiovascular disease

Autor: Zain Jafar, Javier Valero-Elizondo, Gul Jana Saeed, Isaac Acquah, Tamer Yahya, Shiwani Mahajan, Reed Mszar, Safi U. Khan, Miguel Caínzos-Achirica, Khurram Nasir

Publikováno v: American Journal of Preventive Cardiology, Vol 3, Iss , Pp 100084- (2020)

Objective: Atherosclerotic cardiovascular disease (ASCVD) and chronic obstructive pulmonary disease (COPD) are among the leading causes of morbidity, mortality, and economic burden in the United States (US). While previous reports have shown that an

Externí odkaz: https://doaj.org/article/a4eda3178fb7491c989320ea27eaa899

Clinical Determinants and Prognosis of Left Ventricular Reverse Remodelling in Non-Ischemic Dilated Cardiomyopathy

Autor: Carles Díez-López, Joel Salazar-Mendiguchía, Elena García-Romero, Lara Fuentes, Josep Lupón, Antoni Bayés-Genis, Nicolás Manito, Marta de Antonio, Pedro Moliner, Elisabet Zamora, Pablo Catalá-Ruiz, Miguel Caínzos-Achirica, Josep Comín-Colet, José González-Costello

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 9, Iss 1, p 20 (2022)

Aims: Non-ischaemic dilated cardiomyopathy (NIDCM) is characterized by left ventricular (LV) chamber enlargement and systolic dysfunction in the absence of coronary artery disease. Left ventricular reverse remodelling (LVRR) is the ability of a dilat

Externí odkaz: https://doaj.org/article/9e14b03f01cd4564adc4c588ba1dd3d6

Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults

Autor: Martin Bødtker Mortensen, Miguel Caínzos-Achirica, Flemming Hald Steffensen, Hans Erik Bøtker, Jesper Møller Jensen, Niels Peter Rønnow Sand, Michael Maeng, Jens Meldgaard Bruun, Michael J. Blaha, Henrik Toft Sørensen, Manan Pareek, Khurram Nasir, Bjarne L. Nørgaard

Publikováno v: Mortensen, M B, Caínzos-Achirica, M, Steffensen, F H, Bøtker, H E, Jensen, J M, Sand, N P R, Maeng, M, Bruun, J M, Blaha, M J, Sørensen, H T, Pareek, M, Nasir, K & Nørgaard, B L 2022, ' Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults ', JAMA Network Open, vol. 5, no. 2, e2148139 . https://doi.org/10.1001/jamanetworkopen.2021.48139
Mortensen, M B, Caínzos-Achirica, M, Steffensen, F H, Bøtker, H E, Jensen, J M, Sand, N P R, Maeng, M, Bruun, J M, Blaha, M J, Sørensen, H T, Pareek, M, Nasir, K & Nørgaard, B L 2022, ' Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults ', JAMA network open, vol. 5, no. 2, e2148139 . https://doi.org/10.1001/jamanetworkopen.2021.48139

Importance: Atherosclerosis burden and coronary artery calcium (CAC) are associated with the risk for atherosclerotic cardiovascular disease (ASCVD) events, with absence of plaque and CAC indicating low risk. Whether this is true in patients with ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f6306dbf3f736270e28ec6f4d9ca83
https://pubmed.ncbi.nlm.nih.gov/35147692

Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults.

Autor: Mortensen, Martin Bødtker, Caínzos-Achirica, Miguel, Steffensen, Flemming Hald, Bøtker, Hans Erik, Jensen, Jesper Møller, Sand, Niels Peter Rønnow, Maeng, Michael, Bruun, Jens Meldgaard, Blaha, Michael J., Sørensen, Henrik Toft, Pareek, Manan, Nasir, Khurram, Nørgaard, Bjarne L.

Publikováno v: JAMA Network Open; 2/11/2022, Vol. 5 Issue 2, pe2148139-e2148139, 1p