Development of a Prodrug of Camptothecin for Enhanced Treatment of Glioblastoma Multiforme

Autor: Cristina Soto-Sánchez, Pablo Botella, Eduardo Fernández, Elisa Checa-Chavarria, Gema Martinez Navarrete, Miguel Angel Sanchez Martos, Eva Rivero-Buceta

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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Digital.CSIC. Repositorio Institucional del CSIC
Molecular Pharmaceutics

A novel therapeutic approach for glioblastoma multiforme (GBM) therapy has been carried out through in vitro and in vivo testing by using the prodrug camptothecin-20-O-(5-aminolevulinate) (CPT-ALA). The incorporation of ALA to CPT may promote uptake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168c06a7d1c910631f0c647ea7bc4389
http://hdl.handle.net/10261/268142