Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Miguel Angel Merlos Rodrigo"'
Autor:
Miguel Angel Merlos Rodrigo, Hana Michalkova, Ana Maria Jimenez Jimenez, Frantisek Petrlak, Tomas Do, Ladislav Sivak, Yazan Haddad, Petra Kubickova, Vivian de los Rios, J. Ignacio Casal, Marina Serrano-Macia, Teresa C. Delgado, Loreto Boix, Jordi Bruix, Maria L. Martinez Chantar, Vojtech Adam, Zbynek Heger
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Background & aims Metallothionein-3 (hMT3) is a structurally unique member of the metallothioneins family of low-mass cysteine-rich proteins. hMT3 has poorly characterized functions, and its importance for hepatocellular carcinoma (HCC) cell
Externí odkaz:
https://doaj.org/article/7a0c75ad3012498a9f15fd7e736949c9
Autor:
Katerina Mitrevska, Miguel Angel Merlos Rodrigo, Natalia Cernei, Hana Michalkova, Zbynek Splichal, David Hynek, Ondrej Zitka, Zbynek Heger, Pavel Kopel, Vojtech Adam, Vedran Milosavljevic
Publikováno v:
Materials Today Bio, Vol 19, Iss , Pp 100570- (2023)
The combination of in ovo and ex ovo chorioallantoic membrane (CAM) assay provides an excellent platform which extends its relevance in studying carcinogenesis to the field of screening of anticancer activity of platinum nanoparticles (PtNPs) and fur
Externí odkaz:
https://doaj.org/article/47d5ea2b873e41f8a37cfe70229958c8
Autor:
Miguel Angel Merlos Rodrigo, Hana Michalkova, Vladislav Strmiska, Berta Casar, Piero Crespo, Vivian de los Rios, J. Ignacio Casal, Yazan Haddad, Roman Guran, Tomas Eckschlager, Petra Pokorna, Zbynek Heger, Vojtech Adam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Metallothionein-3 has poorly characterized functions in neuroblastoma. Cisplatin-based chemotherapy is a major regimen to treat neuroblastoma, but its clinical efficacy is limited by chemoresistance. We investigated the impact of human metal
Externí odkaz:
https://doaj.org/article/c380e720965d4d49b73aadef566e6723
Autor:
Vedran Milosavljevic, Yazan Haddad, Miguel Angel Merlos Rodrigo, Amitava Moulick, Hana Polanska, David Hynek, Zbynek Heger, Pavel Kopel, Vojtech Adam
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0270734 (2022)
[This corrects the article DOI: 10.1371/journal.pone.0163983.].
Externí odkaz:
https://doaj.org/article/4c81043b58c244adb519870dc4dab8d9
Autor:
Yazan Haddad, Marketa Charousova, Hana Zivotska, Zbynek Splichal, Miguel Angel Merlos Rodrigo, Hana Michalkova, Sona Krizkova, Barbora Tesarova, Lukas Richtera, Petr Vitek, Kamila Stokowa-Soltys, David Hynek, Vedran Milosavljevic, Simona Rex, Zbynek Heger
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-20 (2020)
Abstract Background Currently, the diagnosis and treatment of neuroblastomas—the most frequent solid tumors in children—exploit the norepinephrine transporter (hNET) via radiolabeled norepinephrine analogs. We aim to develop a nanomedicine-based
Externí odkaz:
https://doaj.org/article/73fe3960cf4f45d9b8468c2fdd75c8aa
Autor:
Miguel Angel Merlos Rodrigo, Berta Casar, Hana Michalkova, Ana Maria Jimenez Jimenez, Zbynek Heger, Vojtech Adam
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe chick chorioallantoic membrane (CAM) assay can provide an alternative versatile, cost-effective, and ethically less controversial in vivo model for reliable screening of drugs. In the presented work, we demonstrate that CAM assay (in ovo a
Externí odkaz:
https://doaj.org/article/cb227be5fe354aacabdcb1816ddbcb0f
Autor:
Jan Hraběta, Marie Belhajová, Hana Šubrtová, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Tomáš Eckschlager
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4392 (2020)
Resistance to chemotherapeutics and targeted drugs is one of the main problems in successful cancer therapy. Various mechanisms have been identified to contribute to drug resistance. One of those mechanisms is lysosome-mediated drug resistance. Lysos
Externí odkaz:
https://doaj.org/article/2a64c230c017427d8d42287fa6476bfb
Autor:
Vedran Milosavljevic, Yazan Haddad, Miguel Angel Merlos Rodrigo, Amitava Moulick, Hana Polanska, David Hynek, Zbynek Heger, Pavel Kopel, Vojtech Adam
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204441 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0163983.].
Externí odkaz:
https://doaj.org/article/8a15f1049d8b4f968036a59dc5ba4be6
Autor:
Miguel Angel Merlos Rodrigo, Hana Buchtelova, Ana Maria Jimenez Jimenez, Pavlina Adam, Petr Babula, Zbynek Heger, Vojtech Adam
Publikováno v:
Cells, Vol 8, Iss 3, p 235 (2019)
The efficiency of cisplatin (CDDP) is significantly hindered by the development of resistance during the treatment course. To gain a detailed understanding of the molecular mechanisms underlying the development of cisplatin resistance, we comparative
Externí odkaz:
https://doaj.org/article/ff8031c230b74b17bfa58469496576a0
Autor:
Rene Kizek, Libuse Trnkova, Petr Babula, Jaromir Hubalek, Vojtech Adam, Miguel Angel Merlos Rodrigo, Pavel Kopel, Ludmila Krejcova, David Hynek
Publikováno v:
Viruses, Vol 5, Iss 7, Pp 1719-1739 (2013)
Since its first official detection in the Guangdong province of China in 1996, the highly pathogenic avian influenza virus of H5N1 subtype (HPAI H5N1) has reportedly been the cause of outbreaks in birds in more than 60 countries, 24 of which were Eur
Externí odkaz:
https://doaj.org/article/e79c4db53eff4b22a5c45ed9d65ad964