Role of the Endogenous Cannabinoid System in the Regulation of Motor Activity

Autor: Fernando Rodrı́guez de Fonseca, Ignacio Del Arco, José Luis Martı́n-Calderón, Miguel Angel Gorriti, Miguel Navarro

Publikováno v: Neurobiology of Disease, Vol 5, Iss 6, Pp 483-501 (1998)

One of the prominent pharmacological features of drugs acting at the brain cannabinoid receptor (CB1) is the induction of alterations in motor behavior. Catalepsy, immobility, ataxia, or the impairment of complex behavioral acts are observed after ac

Externí odkaz: https://doaj.org/article/69135b9308944932ade4aea9d6db9b6d

Functional Interactions between Endogenous Cannabinoid and Opioid Systems: Focus on Alcohol, Genetics and Drug-Addicted Behaviors

Autor: José Antonio López-Moreno, Miguel Angel Gorriti, F. Rodríguez de Fonseca, A. Lopez-Jimenez

Publikováno v: Current Drug Targets. 11:406-428

Although the first studies regarding the endogenous opioid system and addiction were published during the 1940s, addiction and cannabinoids were not addressed until the 1970s. Currently, the number of opioid addiction studies indexed in PubMed-Medlin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e59f6204a77e074df03d977e9115733
https://doi.org/10.2174/138945010790980312

The anandamide transport inhibitor AM404 reduces ethanol self-administration

Autor: Fernando Rodríguez de Fonseca, Maurizio Massi, Miguel Navarro, Roberto Ciccocioppo, Ainhoa Bilbao, Andrea Cippitelli, Daniele Piomelli, Miguel Angel Gorriti

Publikováno v: European Journal of Neuroscience. 26:476-486

The endocannabinoid system mediates in the pharmacological actions of ethanol and genetic studies link endocannabinoid signaling to alcoholism. Drugs activating cannabinoid CB1 receptors have been found to promote alcohol consumption but their effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11c4ef967db526f4d42b66ef2153d825
https://doi.org/10.1111/j.1460-9568.2007.05665.x

Acute administration of reboxetine reduces alcohol self-administration but, after a subchronic treatment with this drug, alcohol self-administration is enhanced

Autor: J. Suarez, Manuel Vázquez, Miguel Angel Gorriti, F. Rodríguez de Fonseca, T. Marban Castro, M. Jaimez-Alameda, Francisco Alén, Antonia Serrano, M. Anton Valades, R. Gómez de Heras, María Teresa Ramírez-López, D. Ouco, A.J. Ballesta-Garcia, N. Blanco

Publikováno v: European Psychiatry. 33:S410-S411

IntroductionComorbidity between alcoholism and depression has long been acknowledged, and the possibility that similar brain mechanisms, involving both serotonergic (5-HT) and noradrenergic systems (NE), underlie both pathologies has been suggested.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6ca206adfd2ac11db2e84112fb44673
https://doi.org/10.1016/j.eurpsy.2016.01.1483

Role of the endogenous cannabinoid system as a modulator of dopamine transmission: Implications for Parkinson’s disease and schizophrenia

Autor: Fernando Rodríguez de Fonseca, Luis M. Garcia-Segura, Miguel Navarro, Ainhoa Bilbao, Miguel Angel Gorriti, Leticia Escuredo, Daniele Piomelli

Publikováno v: Rodríguez de Fonseca, F; Gorriti, MA; Bilbao, A; Escuredo, L; García-Segura, LM; Piomelli, D; et al.(2001). Role of the endogenous cannabinoid system as a modulator of dopamine transmission: Implications for Parkinson's disease and schizophrenia. Neurotoxicity Research, 3(1), 23-35. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/002464bk
Scopus-Elsevier

The endogenous cannabinoid system is a new signaling system composed by the central (CB1) and the peripheral (CB2) receptors, and several lipid transmitters including anandamide and 2-arachidonylglycerol. This system is the target of natural cannabin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7b74850e48cdcee370b3d3be8e78b6
https://doi.org/10.1007/bf03033228