Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Miguel Angel, Chiurillo"'
Autor:
Thaise Lara Teixeira, Miguel Angel Chiurillo, Noelia Lander, Cassiano Costa Rodrigues, Thiago Souza Onofre, Éden Ramalho Ferreira, Camila Miyagui Yonamine, Júlia de Gouveia Santos, Renato Arruda Mortara, Claudio Vieira da Silva, José Franco da Silveira
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
P21 is an immunomodulatory protein expressed throughout the life cycle of Trypanosoma cruzi, the etiologic agent of Chagas disease. In vitro and in vivo studies have shown that P21 plays an important role in the invasion of mammalian host cells and e
Externí odkaz:
https://doaj.org/article/5b2466fd38424206849d38a7812c6afa
Publikováno v:
Archives of Endocrinology and Metabolism, Vol 60, Iss 3, Pp 246-251 (2015)
Objective The global burden of diabetes mellitus will impact strongly American countries in the coming decades. Type 2 diabetes mellitus (T2DM) is a multifactorial disease and the basis for its genetic susceptibility remains not fully understood. Dif
Externí odkaz:
https://doaj.org/article/a403c252dca442fb93e1698347984fac
Publikováno v:
Microbiology Spectrum
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Protein phosphorylation is involved in several key biological roles in the complex life cycle of Trypanosoma cruzi, the etiological agent of Chagas disease, and protein kinases are potential drug targets. Here, we report that the AGC essential kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1bd517b9a78c35ad6c5b172c2a6e276
https://doi.org/10.1128/spectrum.00738-21
https://doi.org/10.1128/spectrum.00738-21
Autor:
Thaise Lara, Teixeira, Miguel Angel, Chiurillo, Noelia, Lander, Cassiano Costa, Rodrigues, Thiago Souza, Onofre, Éden Ramalho, Ferreira, Camila Miyagui, Yonamine, Júlia de Gouveia, Santos, Renato Arruda, Mortara, Claudio Vieira, da Silva, José Franco, da Silveira
Publikováno v:
Frontiers in cellular and infection microbiology. 12
P21 is an immunomodulatory protein expressed throughout the life cycle of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1499b281bd2ad121380461955f320456
https://pubmed.ncbi.nlm.nih.gov/35252026
https://pubmed.ncbi.nlm.nih.gov/35252026
Autor:
Newton Valério Verbisck, Márcia Regina Machado dos Santos, David M Engman, Miguel Angel Chiurillo, José Luis Ramirez, Jorge Enrique Araya, Renato Arruda Mortara, José Franco da Silveira
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 98, Iss 1, Pp 129-133 (2003)
We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi. Steady-state level of transcripts of this sequence family appeared to be developme
Externí odkaz:
https://doaj.org/article/a8c1ce22a9054e1584ed4e889badd9ca
Autor:
Miguel Angel Chiurillo, Noelia Lander
Publikováno v:
J Eukaryot Microbiol
CRISPR/Cas9 technology has revolutionized biology. This prokaryotic defense system against foreign DNA has been repurposed for genome editing in a broad range of cell tissues and organisms. Trypanosomatids are flagellated protozoa belonging to the or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a89e6c6f0417b4464abec485c9f2e0b
https://doi.org/10.1111/jeu.12747
https://doi.org/10.1111/jeu.12747
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 3, Pp 343-346 (2002)
Here we have characterized Leishmania major (Friedlin) telomeric terminus (the very end) using recombinants obtained by a vector-adaptor cloning protocol. As in L. donovani, the last nine nucleotides of L. major terminus are 5'-GGTTAGGGT-OH 3', diffe
Externí odkaz:
https://doaj.org/article/ae00b093b1ea40b78de13a1c53462a8d
Autor:
Patrícia Hermes Stoco, Glauber Wagner, Carlos Talavera-Lopez, Alexandra Gerber, Arnaldo Zaha, Claudia Elizabeth Thompson, Daniella Castanheira Bartholomeu, Débora Denardin Lückemeyer, Diana Bahia, Elgion Loreto, Elisa Beatriz Prestes, Fábio Mitsuo Lima, Gabriela Rodrigues-Luiz, Gustavo Adolfo Vallejo, José Franco da Silveira Filho, Sérgio Schenkman, Karina Mariante Monteiro, Kevin Morris Tyler, Luiz Gonzaga Paula de Almeida, Mauro Freitas Ortiz, Miguel Angel Chiurillo, Milene Höehr de Moraes, Oberdan de Lima Cunha, Rondon Mendonça-Neto, Rosane Silva, Santuza Maria Ribeiro Teixeira, Silvane Maria Fonseca Murta, Thais Cristine Marques Sincero, Tiago Antonio de Oliveira Mendes, Turán Peter Urmenyi, Viviane Grazielle Silva, Wanderson Duarte DaRocha, Björn Andersson, Alvaro José Romanha, Mário Steindel, Ana Tereza Ribeiro de Vasconcelos, Edmundo Carlos Grisard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3176 (2014)
Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans and other wild and domestic mammals across Central and South America. It does not cause human disease, but it can be mistaken for the etiologic agent of Chagas disease, Trypa
Externí odkaz:
https://doaj.org/article/273adbbc20c343ca9c85932103282936
Autor:
Noelia Lander, Miguel Angel Chiurillo, Roberto Docampo, Ana Catarina Rezende Leite, Anibal E. Vercesi, Guilherme Rodrigo R M Dos Santos
Publikováno v:
The FASEB Journal. 35
Leucine zipper-EF-hand containing transmembrane protein 1 (Letm1) is a mitochondrial inner membrane protein involved in Ca2+ and K+ homeostasis in mammalian cells. Here, we demonstrate that the Letm1 orthologue of Trypanosoma cruzi, the etiologic age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d2489a681b3f8450ce52b4590e4f64c
https://doi.org/10.1096/fj.202100120rr
https://doi.org/10.1096/fj.202100120rr
Autor:
Raquel S. Negreiros, Roberto Docampo, Noelia Lander, Anibal E. Vercesi, Miguel Angel Chiurillo
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
Trypanosoma cruzi is the causative agent of Chagas disease. Pyruvate is the end product of glycolysis, and its transport into the mitochondrion is mediated by the mitochondrial pyruvate carrier (MPC) subunits.
Pyruvate is the final metabolite of
Pyruvate is the final metabolite of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5898277f7cc13adf56fdecbb918acfee
https://doi.org/10.1128/mbio.00540-21
https://doi.org/10.1128/mbio.00540-21