Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Miguel Albuquerque"'
Autor:
Sonia Frendi, Chloé Martineau, Hélène Cazier, Rémy Nicolle, Anaïs Chassac, Miguel Albuquerque, Jérôme Raffenne, Julie Le Faouder, Valérie Paradis, Jérôme Cros, Anne Couvelard, Vinciane Rebours
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Although pancreatic precancerous lesions are known to be related to obesity and fatty pancreatic infiltration, the mechanisms remain unclear. We assessed the role of fatty infiltration in the process of pancreatic oncogenesis and obesity. A
Externí odkaz:
https://doaj.org/article/43883c2326d1432e9d151e071d492431
Primary liver cancer classification from routine tumour biopsy using weakly supervised deep learning
Autor:
Aurélie Beaufrère, Nora Ouzir, Paul Emile Zafar, Astrid Laurent-Bellue, Miguel Albuquerque, Gwladys Lubuela, Jules Grégory, Catherine Guettier, Kévin Mondet, Jean-Christophe Pesquet, Valérie Paradis
Publikováno v:
JHEP Reports, Vol 6, Iss 3, Pp 101008- (2024)
Background & Aims: The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly sup
Externí odkaz:
https://doaj.org/article/810dc17bccbc49af88039d6984aa7ea6
A new NRF2 activator for the treatment of human metabolic dysfunction-associated fatty liver disease
Autor:
Adel Hammoutene, Samira Laouirem, Miguel Albuquerque, Nathalie Colnot, Angélique Brzustowski, Dominique Valla, Nicolas Provost, Philippe Delerive, Valérie Paradis
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100845- (2023)
Background & Aims: Oxidative stress triggers metabolic-associated fatty liver disease (MAFLD) and fibrosis. Previous animal studies demonstrated that the transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2), the master regulator of
Externí odkaz:
https://doaj.org/article/797f996f516a4f5ebd96f64fabc15d6d
Autor:
Maxime K. Collard, Julien Tourneur-Marsille, Mathieu Uzzan, Miguel Albuquerque, Maryline Roy, Anne Dumay, Jean-Noël Freund, Jean-Pierre Hugot, Nathalie Guedj, Xavier Treton, Yves Panis, Eric Ogier-Denis
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 665-687 (2023)
Background & Aims: Although appendectomy may reduce colorectal inflammation in patients with ulcerative colitis (UC), this surgical procedure has been suggested to be associated with an increased risk of colitis-associated cancer (CAC). Our aim was t
Externí odkaz:
https://doaj.org/article/894e082372e54f2ba6b9d0ae5b45f5f6
Autor:
Audrey Laurain, Isabelle Rubera, Micheline Razzouk-Cadet, Stéphanie Bonnafous, Miguel Albuquerque, Valérie Paradis, Stéphanie Patouraux, Christophe Duranton, Olivier Lesaux, Georges Lefthériotis, Albert Tran, Rodolphe Anty, Philippe Gual, Antonio Iannelli, Guillaume Favre
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1496 (2022)
Liver fibrosis is associated with arterial calcification (AC). Since the liver is a source of inorganic pyrophosphate (PPi), an anti-calcifying compound, we investigated the relationship between plasma PPi ([PPi]pl), liver fibrosis, liver function, A
Externí odkaz:
https://doaj.org/article/d6db8d60a64c47cf92486e161bb4a866
Autor:
Pushpa Hegde, Emmanuel Weiss, Valérie Paradis, Jinghong Wan, Morgane Mabire, Sukriti Sukriti, Pierre-Emmanuel Rautou, Miguel Albuquerque, Olivia Picq, Abhishak Chandra Gupta, Gladys Ferrere, Hélène Gilgenkrantz, Badr Kiaf, Amine Toubal, Lucie Beaudoin, Philippe Lettéron, Richard Moreau, Agnès Lehuen, Sophie Lotersztajn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Hepatic fibrosis represents the liver response to chronic injury and can lead to cirrhosis. Here the authors show that mucosal-associated invariant T cells mediate chronic inflammation and fibrogenesis in the liver by inducing a proinflammatory pheno
Externí odkaz:
https://doaj.org/article/68dba654aed943aea66393450ba3bbd9
Autor:
Maxime Ronot, Simon A Lambert, Mathilde Wagner, Philippe Garteiser, Sabrina Doblas, Miguel Albuquerque, Valérie Paradis, Valérie Vilgrain, Ralph Sinkus, Bernard E Van Beers
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94679 (2014)
OBJECTIVE: To assess in a high-resolution model of thin liver rat slices which viscoelastic parameter at three-dimensional multifrequency MR elastography has the best diagnostic performance for quantifying liver fibrosis. MATERIALS AND METHODS: The s
Externí odkaz:
https://doaj.org/article/7ae02160e0274ebc800e7c0c867bf14c
Autor:
Bellili, Djamila, Bessadi, Ouarda, Da Silveira, Charlene, Djelouat, Fatima Zohra, Girard, Benoit, Legrand, Vanessa, Neveux, Nathalie, Meziani, Meriam, Roy, Ludovic, Sekour, Dahia, Sens, Manon, Slimani, Miassa, Zatout, Ouassila, Bachelet, Delphine, Bhavsar, Krishna, Mullaert, Basma Basli-Baillet Jimmy, Marcault, Estelle, Si-Mohammed, Nassima, Cosson, Emmanuel, Miguel Albuquerque, Doblas, Sabrina, Hammoutene, Adel, Gonzalez Montpetit, Estefania, Pagé, Gwenaël, Béatrice Parfait, Postic, Catherine, Lehuen, Agnès, Toubal, Amine, Rousseau, Camille, Fruchet, Blandine, Soulard, Pauline, Gouda, Zouriatou, Vidaud, Michel, Letourneur, Franck, Renault, Gilles, Scharfmann, Raphaël, Ait-Boudaoud, Amel, Barsamian, Charles, Carette, Claire, Rives-Lange, Claire, Baida, Rachel, Couture, Olivier, Decombas, Sofiane, Deffieux, Thomas, Nguyen, Thu-mai, Tanter, Mickael, Baltauss, Tania, Balzac, Edwige-Ludiwyne, Barbier Saint Hilaire, Pierre, Delerive, Philippe, Duvivier, Valérie, Fillon, Arnaud, Geronimi, Julia, Laplume, Jessica, Werner, Erwan, Xuereb, Laura, Liechti, Robin, Martin, Olivier, Mehl, Florence, Pruess, Manuela, Castille, Jean-Marie, Drane, Fabienne, Deckmyn, Olivier, Castelli, Florence, Cousin, Benoit Colsch Emmanuel, Fenaille, François, Guilbaud, Laure, Lohier, Allyre, Chambellin, Francois, Laaland, Lyddie, Clusel, Catherine, Hauduroy, Marie, Pautre, Pierre, Castera, Laurent, Garteiser, Philippe, Laouenan, Cédric, Vidal-Trécan, Tiphaine, Vallet-Pichard, Anaïs, Manchon, Pauline, Paradis, Valérie, Czernichow, Sébastien, Roulot, Dominique, Larger, Etienne, Pol, Stanislas, Bedossa, Pierre, Correas, Jean-Michel, Valla, Dominique, Gautier, Jean-François, Van Beers, Bernard E.
Publikováno v:
In Journal of Hepatology August 2024 81(2):195-206
Autor:
Vinciane Rebours, Miguel Albuquerque, Alain Sauvanet, Philippe Ruszniewski, Philippe Lévy, Valérie Paradis, Pierre Bedossa, Anne Couvelard
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76229 (2013)
Pancreatic stellate cells (PSC) are involved in fibrogenesis and oncogenesis by modulating the extracellular matrix.To evaluate the effect of cellular stress on PSC activation using a model of normal human pancreatic tissue slices culture preserving
Externí odkaz:
https://doaj.org/article/ccbd35da09dc40909b02df187f0f3bec
Autor:
Loïc Trapani, Aurélie Beaufrère, Christian Hobeika, Tatiana Codjia, Miguel Albuquerque, Mohamed Bouattour, Mickael Lesurtel, François Cauchy, Valérie Paradis
Publikováno v:
Histopathology.