Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Miguel A. Pérez-Pinzón"'
Autor:
Kunjan R. Dave, Ami P. Raval, Jesús Purroy, Ilias G. Kirkinezos, Carlos T. Moraes, Walter G. Bradley, Miguel A. Pérez-Pinzón
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 126-133 (2005)
Protein kinase C (PKC) was suggested to play a role in the pathology of amyotrophic lateral sclerosis (ALS) patients. Activation of PKC delta (δPKC) modulates mitochondrially induced apoptosis. The goal of the present study was to define whether δP
Externí odkaz:
https://doaj.org/article/4fe0b2119d044d27be734cb168c62a6a
Autor:
Gary K. Steinberg, Nariman Panahian, Miguel A. Pérez-Pinzón, Guo-Hua Sun, Marlene W. Modi, Jerry Sepinwall
Publikováno v:
Neurobiology of Disease, Vol 2, Iss 2, Pp 109-118 (1995)
N-methyl-d-aspartate (NMDA) receptor antagonists have been shown to protect against focal cerebral ischaemia when administered either before or soon after the onset of ischaemia. However, the precise therapeutic window for protection using these drug
Externí odkaz:
https://doaj.org/article/6f6bca0832854a4d99ef83d8cfbb33b5
Autor:
Eric Fagerli, Charles W. Jackson, Iris Escobar, Fernando J. Ferrier, Efrain J. Perez Lao, Isabel Saul, Jorge Gomez, Kunjan R. Dave, Oliver Bracko, Miguel A. Perez-Pinzon
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 984 (2024)
Vascular cognitive impairment and dementia (VCID) is the second leading cause of dementia. There is currently no effective treatment for VCID. Resveratrol (RSV) is considered an antioxidant; however, our group has observed pleiotropic effects in stro
Externí odkaz:
https://doaj.org/article/0c25d7ebbefb41b6b1afe1c0e5914e91
Cerebral preconditioning is a phenomenon wherein a mild insult or stress induces cellular and tissue adaptation or tolerance to a later, severe injury, therefore reflecting the efficacy of endogenous mechanisms of cerebrovascular protection. Initiall
Autor:
Eric Fagerli, Iris Escobar, Fernando J. Ferrier, Charles W. Jackson, Efrain J. Perez-Lao, Miguel A. Perez-Pinzon
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Sirtuins are an evolutionarily conserved family of regulatory proteins that function in an NAD+ -dependent manner. The mammalian family of sirtuins is composed of seven histone deacetylase and ADP-ribosyltransferase proteins (SIRT1-SIRT7) that are fo
Externí odkaz:
https://doaj.org/article/f62d38df2ffe4a01838d28c1fadf6a68
Autor:
Shahil H. Patel, Alba Timón-Gómez, Hari Pradhyumnan, Berk Mankaliye, Kunjan R. Dave, Miguel A. Perez-Pinzon, Ami P. Raval
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16075 (2022)
Smoking-derived nicotine (N) and oral contraceptive (OC) synergistically exacerbate ischemic brain damage in females, and the underlying mechanisms remain elusive. In a previous study, we showed that N + OC exposure altered brain glucose metabolism i
Externí odkaz:
https://doaj.org/article/39d3845fc487419fa5dbc79a0bd31560
Autor:
Ashish K. Rehni, Sunjoo Cho, Zhexuan Zhang, Priyanka Khushal, Ami P. Raval, Sebastian Koch, Miguel A. Perez-Pinzon, Weizhao Zhao, Wenche Jy, Kunjan R. Dave
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15167 (2022)
Spontaneous intracerebral hemorrhage (sICH) is a disabling stroke sub-type, and tobacco use is a prominent risk factor for sICH. We showed that chronic nicotine exposure enhances bleeding post-sICH. Reduction of hematoma growth is a promising effecti
Externí odkaz:
https://doaj.org/article/cea1dc00373f4479b2bc7e704e736697
Autor:
Ashish K. Rehni, Sunjoo Cho, Zhexuan Zhang, Weizhao Zhao, Ami P. Raval, Miguel A. Perez-Pinzon, Kunjan R. Dave
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 621 (2022)
Spontaneous intracerebral hemorrhage (sICH) is a deadly stroke subtype, and tobacco use increases sICH risk. However epidemiological studies show that, there are no confirmatory studies showing the effect of tobacco use on sICH outcome. Therefore, we
Externí odkaz:
https://doaj.org/article/b5d282e95f4843328a861cf6c12c066d
Autor:
Miguel A. Pérez-Pinzón
Publikováno v:
Journal of Bioenergetics & Biomembranes; Aug2004, Vol. 36 Issue 4, p323-327, 5p