Zobrazeno 1 - 10
of 712
pro vyhledávání: '"Miguel A. Molina"'
Autor:
Rodrigo de Oliveira Cavagna, Edilene Santos de Andrade, Monise Tadin Reis, Flávia Escremim de Paula, Gustavo Noriz Berardinelli, Murilo Bonatelli, Gustavo Ramos Teixeira, Beatriz Garbe Zaniolo, Josiane Mourão Dias, Flávio Augusto Ferreira da Silva, Carlos Eduardo Baston Silva, Marina Xavier Reis, Erika Lopes Maia, Thainara Santos de Alencar, Alexandre Arthur Jacinto, Rachid Eduardo Noleto da Nóbrega Oliveira, Miguel A. Molina-Vila, Letícia Ferro Leal, Rui Manuel Reis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract NTRK1, 2, and 3 fusions are important therapeutic targets for NSCLC patients, but their prevalence in South American admixed populations needs to be better explored. NTRK fusion detection in small biopsies is a challenge, and distinct method
Externí odkaz:
https://doaj.org/article/859d3b2ebdf74c9bad341755af15f1df
Autor:
Ana Giménez‐Capitán, Estela Sánchez‐Herrero, Lucía Robado de Lope, Andrés Aguilar‐Hernández, Ivana Sullivan, Virginia Calvo, Irene Moya‐Horno, Santiago Viteri, Carlos Cabrera, Cristina Aguado, Noelia Armiger, Joselyn Valarezo, Clara Mayo‐de‐las‐Casas, Noemí Reguart, Rafael Rosell, Mariano Provencio, Atocha Romero, Miguel A. Molina‐Vila
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1884-1897 (2023)
ALK, ROS1, and RET fusions and MET∆ex14 variant associate with response to targeted therapies in non‐small‐cell lung cancer (NSCLC). Technologies for fusion testing in tissue must be adapted to liquid biopsies, which are often the only material
Externí odkaz:
https://doaj.org/article/895f32ea609d4f95922800c025292cd9
Publikováno v:
Sensors, Vol 24, Iss 12, p 3777 (2024)
Breast cancer is the second most common cancer worldwide, primarily affecting women, while histopathological image analysis is one of the possibile methods used to determine tumor malignancy. Regarding image analysis, the application of deep learning
Externí odkaz:
https://doaj.org/article/f8bd866dd75e4a97bc6fbae14ca7e619
Autor:
Jordi Bertran-Alamillo, Ana Giménez-Capitán, Ruth Román, Sara Talbot, Rebecca Whiteley, Nicolas Floc’h, Elizabeth Martínez-Pérez, Matthew J. Martin, Paul D. Smith, Ivana Sullivan, Mikkel G. Terp, Jamal Saeh, Cristina Marino-Buslje, Giulia Fabbri, Grace Guo, Man Xu, Cristian Tornador, Andrés Aguilar-Hernández, Noemí Reguart, Henrik J. Ditzel, Alejandro Martínez-Bueno, Núria Nabau-Moretó, Amaya Gascó, Rafael Rosell, J. Elizabeth Pease, Urszula M. Polanska, Jon Travers, Jelena Urosevic, Miguel A. Molina-Vila
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-24 (2023)
Abstract Background Drugs targeting the spindle assembly checkpoint (SAC), such as inhibitors of Aurora kinase B (AURKB) and dual specific protein kinase TTK, are in different stages of clinical development. However, cell response to SAC abrogation i
Externí odkaz:
https://doaj.org/article/0503e7da1cca40afa0953e96d2560af7
Autor:
José A. Rodríguez-Rodríguez, Ezequiel López-Rubio, Juan A. Ángel-Ruiz, Miguel A. Molina-Cabello
Publikováno v:
Sensors, Vol 24, Iss 3, p 821 (2024)
The application of deep learning to image and video processing has become increasingly popular nowadays. Employing well-known pre-trained neural networks for detecting and classifying objects in images is beneficial in a wide range of application fie
Externí odkaz:
https://doaj.org/article/13069b93f4ac41c792974a8af8d1b42b
Autor:
Diogo Fortunato, Stavros Giannoukakos, Ana Giménez-Capitán, Michael Hackenberg, Miguel A. Molina-Vila, Nataša Zarovni
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-24 (2022)
Abstract Background Intercellular communication is mediated by extracellular vesicles (EVs), as they enclose selectively packaged biomolecules that can be horizontally transferred from donor to recipient cells. Because all cells constantly generate a
Externí odkaz:
https://doaj.org/article/a32e0c24638f4896964ad6d0c176dec0
Autor:
Maria Gonzalez-Cao, Clara Mayo de las Casas, Juana Oramas, Miguel A. Berciano-Guerrero, Luis de la Cruz, Pablo Cerezuela, Ana Arance, Eva Muñoz-Couselo, Enrique Espinosa, Teresa Puertolas, Roberto Diaz Beveridge, Sebastian Ochenduszko, Maria-Jose Villanueva, Laura Basterretxea, Lorena Bellido, Delvys Rodriguez, Begoña Campos, Clara Montagut, Ana Drozdowskyj, Miguel A. Molina, Jose Antonio Lopez-Martin, Alfonso Berrocal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Whether intermittent strategies of delivering drugs can improve cancer patients survival is still unclear. Here, the authors reports the results of a randomized phase II clinical trial aimed to compare the efficacy and safety of two dosing regimens (
Externí odkaz:
https://doaj.org/article/bcf9c314e06143fd83f1b0b564d0166e
Autor:
Silvia D’Ambrosi, Stavros Giannoukakos, Mafalda Antunes-Ferreira, Carlos Pedraz-Valdunciel, Jillian W. P. Bracht, Nicolas Potie, Ana Gimenez-Capitan, Michael Hackenberg, Alberto Fernandez Hilario, Miguel A. Molina-Vila, Rafael Rosell, Thomas Würdinger, Danijela Koppers-Lalic
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4881 (2023)
Despite the diversity of liquid biopsy transcriptomic repertoire, numerous studies often exploit only a single RNA type signature for diagnostic biomarker potential. This frequently results in insufficient sensitivity and specificity necessary to rea
Externí odkaz:
https://doaj.org/article/508b8d699bbb4150bd895b6180ff88bf
Autor:
Cristina Aguado, Cristina Teixido, Ruth Román, Roxana Reyes, Ana Giménez‐Capitán, Elba Marin, Carlos Cabrera, Nuria Viñolas, Sergi Castillo, Silvia Muñoz, Ainara Arcocha, Laura López‐Vilaró, Ivana Sullivan, Erika Aldeguer, Sonia Rodríguez, Irene Moya, Santiago Viteri, Andrés Felipe Cardona, Ramon Palmero, Cristina Sainz, Miguel Mesa‐Guzmán, Maria D. Lozano, Andrés Aguilar‐Hernández, Alejandro Martínez‐Bueno, María González‐Cao, Elena Gonzalvo, William P. J. Leenders, Rafael Rosell, Luis M. Montuenga, Aleix Prat, Miguel A. Molina‐Vila, Noemi Reguart
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 350-363 (2021)
MET inhibitors have shown activity in non‐small‐cell lung cancer patients (NSCLC) with MET amplification and exon 14 skipping (METΔex14). However, patient stratification is imperfect, and thus, response rates have varied widely. Here, we studied
Externí odkaz:
https://doaj.org/article/5db041644f0248ee90bd178c373b1867
Autor:
Jillian W. P. Bracht, Ana Gimenez-Capitan, Chung-Ying Huang, Nicolas Potie, Carlos Pedraz-Valdunciel, Sarah Warren, Rafael Rosell, Miguel A. Molina-Vila
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Extracellular vesicles (EVs) are double-layered phospholipid membrane vesicles that are released by most cells and can mediate intercellular communication through their RNA cargo. In this study, we tested if the NanoString nCounter platform
Externí odkaz:
https://doaj.org/article/b409b0d38d0943b78e064bba707fd0fb