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pro vyhledávání: '"Miguel A. Manzanares"'
Akademický článek
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Autor:
Alyssa D Fronk, Miguel A Manzanares, Paulina Zheng, Adam Geier, Kendall Anderson, Shaleigh Stanton, Hasan Zumrut, Sakshi Gera, Robin Munch, Vanessa Frederick, Priyanka Dhingra, Gayatri Arun, Martin Akerman
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 676-701 (2024)
Abstract Splice-switching oligonucleotides (SSOs) are antisense compounds that act directly on pre-mRNA to modulate alternative splicing (AS). This study demonstrates the value that artificial intelligence/machine learning (AI/ML) provides for the id
Externí odkaz:
https://doaj.org/article/af0776e556f747fd855724c15473a6ed
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 3, Pp 151304- (2023)
Externí odkaz:
https://doaj.org/article/e6eb540abe724947b9576404b730658e
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 1, Pp 17-27 (2023)
Cancer-associated fibroblasts (CAFs) are a major point of interest in modern oncology. Their interest resides in their ability to favor tumor growth without carrying genetic mutations. From a translational standpoint, they are potential therapeutic t
Externí odkaz:
https://doaj.org/article/bd0e07eede6643deaa4ffffe025fe37d
Autor:
Manuela Escudero-Flórez, David Torres-Hoyos, Yaneth Miranda-Brand, Ryan L. Boudreau, Juan Carlos Gallego-Gómez, Miguel Vicente-Manzanares
Publikováno v:
Viruses, Vol 15, Iss 11, p 2252 (2023)
Ryan L [...]
Externí odkaz:
https://doaj.org/article/787ff7cb44be490ba72a1b56d1158d00
Autor:
Raúl Izquierdo-Serrano, Irene Fernández-Delgado, Olga Moreno-Gonzalo, Enrique Martín-Gayo, Diego Calzada-Fraile, Marta Ramírez-Huesca, Inmaculada Jorge, Emilio Camafeita, Joaquín Abián, Miguel Vicente-Manzanares, Esteban Veiga, Jesús Vázquez, Francisco Sánchez-Madrid
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Communication through cell-cell contacts and extracellular vesicles (EVs) enables immune cells to coordinate their responses against diverse types of pathogens. The function exerted by EVs in this context depends on the proteins and nucleic acids loa
Externí odkaz:
https://doaj.org/article/224fe3e484be403386e2a0ca676882e0
Autor:
Manuela Escudero-Flórez, David Torres-Hoyos, Yaneth Miranda-Brand, Ryan L. Boudreau, Juan Carlos Gallego-Gómez, Miguel Vicente-Manzanares
Publikováno v:
Viruses, Vol 15, Iss 7, p 1437 (2023)
Dengue virus (DENV) is a pathogenic arbovirus that causes human disease. The most severe stage of the disease (severe dengue) is characterized by vascular leakage, hypovolemic shock, and organ failure. Endothelial dysfunction underlies these phenomen
Externí odkaz:
https://doaj.org/article/6352608893284a7abba9bdd53711dbba
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 2, Iss 3, Pp 292-308 (2021)
Phosphorylation of cytoskeletal proteins regulates the dynamics of polymerization, stability, and disassembly of the different types of cytoskeletal polymers. These control the ability of cells to migrate and divide. Mutations and alterations of the
Externí odkaz:
https://doaj.org/article/be675c4783a94ec3a0cde37fd41e3296
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151236- (2022)
tT cells migrate to lymphoid organs to become activated through specific contacts with antigen-presenting cells bearing foreign antigens. During migration and activation, T lymphocytes are exposed not only to diverse biochemical inputs, but also to d
Externí odkaz:
https://doaj.org/article/bbfb9e1cfb8f4e89b88137d325e9778b