Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Miguel A. Idoate"'
Autor:
Jesús Machuca-Aguado, Antonio Félix Conde-Martín, Alejandro Alvarez-Muñoz, Enrique Rodríguez-Zarco, Alfredo Polo-Velasco, Antonio Rueda-Ramos, Rosa Rendón-García, Juan José Ríos-Martin, Miguel A. Idoate
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16060 (2023)
The prognostic and predictive role of tumor-infiltrating lymphocytes (TILs) has been demonstrated in various neoplasms. The few publications that have addressed this topic in high-grade serous ovarian carcinoma (HGSOC) have approached TIL quantificat
Externí odkaz:
https://doaj.org/article/ec6e089434f94725a6be716915d6f202
Autor:
María Páramo, Eva Santamaría, Miguel A. Idoate, Macarena Rodríguez-Fraile, Alberto Benito, Maria Collantes, Gemma Quincoces, Iván Peñuelas, Carmen Berasain, Josepmaria Argemi, Jorge Quiroga, Bruno Sangro, José I. Bilbao, Mercedes Iñarrairaegui
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Lobar selective internal radiation therapy (SIRT) is widely used to treat liver tumors inducing atrophy of the treated lobe and contralateral hypertrophy. The lack of animal model has precluded further investigations to improve this treatmen
Externí odkaz:
https://doaj.org/article/9b8adb35808e471683505cf5bacd215d
Autor:
Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam Blattner, Barbara Worst, Christoph E. Heilig, Katja Beck, Peter Horak, Simon Kreutzfeldt, Elke Paff, Sebastian Stark, Pascal Johann, Florian Selt, Jonas Ecker, Dominik Sturm, Kristian W. Pajtler, Annekathrin Reinhardt, Annika K. Wefers, Philipp Sievers, Azadeh Ebrahimi, Abigail Suwala, Francisco Fernández-Klett, Belén Casalini, Andrey Korshunov, Volker Hovestadt, Felix K. F. Kommoss, Mark Kriegsmann, Matthias Schick, Melanie Bewerunge-Hudler, Till Milde, Olaf Witt, Andreas E. Kulozik, Marcel Kool, Laura Romero-Pérez, Thomas G. P. Grünewald, Thomas Kirchner, Wolfgang Wick, Michael Platten, Andreas Unterberg, Matthias Uhl, Amir Abdollahi, Jürgen Debus, Burkhard Lehner, Christian Thomas, Martin Hasselblatt, Werner Paulus, Christian Hartmann, Ori Staszewski, Marco Prinz, Jürgen Hench, Stephan Frank, Yvonne M. H. Versleijen-Jonkers, Marije E. Weidema, Thomas Mentzel, Klaus Griewank, Enrique de Álava, Juan Díaz Martín, Miguel A. Idoate Gastearena, Kenneth Tou-En Chang, Sharon Yin Yee Low, Adrian Cuevas-Bourdier, Michel Mittelbronn, Martin Mynarek, Stefan Rutkowski, Ulrich Schüller, Viktor F. Mautner, Jens Schittenhelm, Jonathan Serrano, Matija Snuderl, Reinhard Büttner, Thomas Klingebiel, Rolf Buslei, Manfred Gessler, Pieter Wesseling, Winand N. M. Dinjens, Sebastian Brandner, Zane Jaunmuktane, Iben Lyskjær, Peter Schirmacher, Albrecht Stenzinger, Benedikt Brors, Hanno Glimm, Christoph Heining, Oscar M. Tirado, Miguel Sáinz-Jaspeado, Jaume Mora, Javier Alonso, Xavier Garcia del Muro, Sebastian Moran, Manel Esteller, Jamal K. Benhamida, Marc Ladanyi, Eva Wardelmann, Cristina Antonescu, Adrienne Flanagan, Uta Dirksen, Peter Hohenberger, Daniel Baumhoer, Wolfgang Hartmann, Christian Vokuhl, Uta Flucke, Iver Petersen, Gunhild Mechtersheimer, David Capper, David T. W. Jones, Stefan Fröhling, Stefan M. Pfister, Andreas von Deimling
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Sarcomas are morphologically heterogeneous tumours rendering their classification challenging. Here the authors developed a classifier using DNA methylation data from several soft tissue and bone sarcoma subtypes, which has the potential to improve c
Externí odkaz:
https://doaj.org/article/c88e43d5043848c8bc27777e780e6d5b
Autor:
Miguel A. Idoate Gastearena, Álvaro López-Janeiro, Arturo Lecumberri Aznarez, Iñigo Arana-Iñiguez, Francisco Guillén-Grima
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1753 (2022)
Objectives: Immunostimulatory therapies using immune checkpoint blockers show clinical activity in a subset of glioblastoma (GBM) patients. Several inhibitory mechanisms play a relevant role in the immune response to GBM. With the objective of analyz
Externí odkaz:
https://doaj.org/article/d42781ec80334488b266222237a2434a
Publikováno v:
Diagnostics, Vol 12, Iss 2, p 450 (2022)
Osteosarcoma is a primary malignant bone tumor usually arising at the metaphysis of long bones, particularly around the knee. The physis has been regarded as a barrier capable of blocking tumor extension, thus allowing it to preserve their epiphysis
Externí odkaz:
https://doaj.org/article/5de7b869aceb4747a2456a1ca33861fb
Autor:
Alejandro Urdiciain, Elena Erausquin, María V. Zelaya, Idoya Zazpe, José L. Lanciego, Bárbara Meléndez, Juan A. Rey, Miguel A. Idoate, Natalia A. Riobo-Del Galdo, Javier S. Castresana
Publikováno v:
Biology, Vol 10, Iss 6, p 467 (2021)
Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents overexpression of mesenchymal markers Snail, Slug, and N-Cadherin and of the autophagic marke
Externí odkaz:
https://doaj.org/article/bdc0fba0691247a994f9dd392c66f8c4
Autor:
Ariel E. Cariaga-Martínez, Isabel Cortés, Esther García, Vicente Pérez-García, María J. Pajares, Miguel A. Idoate, Javier Redondo-Muñóz, Inés M. Antón, Ana C. Carrera
Publikováno v:
Biology Open, Vol 3, Iss 10, Pp 924-936 (2014)
The acquisition of invasiveness is characteristic of tumor progression. Numerous genetic changes are associated with metastasis, but the mechanism by which a cell becomes invasive remains unclear. Expression of p85β, a regulatory subunit of phosphoi
Externí odkaz:
https://doaj.org/article/f52bdff3710043a4ae543d16b34112db
Publikováno v:
Epigenomes, Vol 2, Iss 1, p 5 (2018)
Glioblastoma is the most common form of glioma, as well as the most aggressive. Patients suffering from this disease have a very poor prognosis. Surgery, radiotherapy, and temozolomide are the only approved treatments nowadays. Panobinostat is a pan-
Externí odkaz:
https://doaj.org/article/678570c32c7a450892e95d2015011c17
Autor:
Miguel A. Idoate‐Gastearena, Jesus Machuca‐Aguado, Inmaculada Trigo‐Sánchez, Pablo Gargallo‐Tatay, Enrique Rodriguez‐Zarco, Carmen Garcia De Sola, Juan Jose Rios‐Martin
Publikováno v:
Journal of Digestive Diseases. 24:142-146
Autor:
Miguel A. Idoate Gastearena
Publikováno v:
Revista Española de Patología. 56:73-75