Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Miguel A. González-Cardenete"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16322 (2023)
Ferruginol is a promising abietane-type antitumor diterpene able to induce apoptosis in SK-Mel-28 human malignant melanoma. We aim to increase this activity by testing the effect of a small library of ferruginol analogues. After a screening of their
Externí odkaz:
https://doaj.org/article/6f9be773170249cd8eeada8c25797272
Autor:
Liliana Betancur-Galvis, Orlando José Jimenez-Jarava, Fatima Rivas, William E. Mendoza-Hernández, Miguel A. González-Cardenete
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1602 (2023)
Combining antiviral drugs with different mechanisms of action can help prevent the development of resistance by attacking the infectious agent through multiple pathways. Additionally, by using faster and more economical screening methods, effective s
Externí odkaz:
https://doaj.org/article/6429c8ca8792433b81997dd6cd0af4c0
Publikováno v:
Viruses, Vol 15, Iss 6, p 1342 (2023)
The abietane diterpene (+)-ferruginol (1), like other natural and semisynthetic abietanes, is distinguished for its interesting pharmacological properties such as antimicrobial activity, including antiviral. In this study, selected C18-functionalized
Externí odkaz:
https://doaj.org/article/ebebb60a7b6a404cb606574bd8c7b201
Publikováno v:
Molecules, Vol 27, Iss 20, p 6890 (2022)
Perylene-based compounds, either naturally occurring or synthetic, have shown interesting biological activities. In this study, we report on the broad-spectrum antifungal properties of two lead amphiphilic perylene bisimides, compounds 4 and 5, which
Externí odkaz:
https://doaj.org/article/6989860f79bc44c2a94a442dc151e006
Autor:
Jelver A. Sierra, Katherine Gilchrist, Jorge H. Tabares-Guevara, Liliana Betancur-Galvis, Jose R. Ramirez-Pineda, Miguel A. González-Cardenete
Publikováno v:
Molecules, Vol 27, Iss 19, p 6684 (2022)
Abietic acid (AA), dehydroabietic acid (DHA) and triptoquinones (TQs) are bioactive abietane-type diterpenoids, which are present in many edible vegetables and medicinal herbs with health-promoting properties. Evidence suggests that beneficial effect
Externí odkaz:
https://doaj.org/article/b6103eb393524b14a437817705bd853e
Autor:
Francisco Javier Miquel-Leal, Natalia González-Zapata, Orlando José Jimenez-Jarava, Yaneth M. Brand, Liliana Betancur-Galvis, Maria Luisa Marín, Miguel A. González-Cardenete
Publikováno v:
Chemistry Proceedings, Vol 8, Iss 1, p 2 (2021)
Virus-induced diseases are very common in our society, and we continuously need new treatments for these challenging infections. We discovered by serendipity some years ago that the molecule 18-(Phthalimide-2-yl)ferruginol, an analogue of the natural
Externí odkaz:
https://doaj.org/article/c37acbb55f124a5d8c6754cd44c42fbe
Autor:
Miguel A. González-Cardenete, Fatima Rivas, Rachel Basset, Marco Stadler, Steffen Hering, José M. Padrón, Ramón J. Zaragozá, María Auxiliadora Dea-Ayuela
Publikováno v:
Antibiotics, Vol 10, Iss 2, p 184 (2021)
The abietane-type diterpenoids are significant bioactive compounds exhibiting a varied range of pharmacological properties. In this study, the first synthesis and biological investigation of the new abietane-diterpenoid (+)-4-epi-liquiditerpenoid aci
Externí odkaz:
https://doaj.org/article/e9097f03b31546a1859fb52f75077f1b
Autor:
Lee S. Agudelo-Gómez, Yaneth Miranda-Brand, David Pérez-Guaita, Miguel A. González-Cardenete, Liliana A. Betancur-Galvis
Publikováno v:
Actualidades Biológicas, Vol 34, Iss 96, Pp 128-129 (2012)
Externí odkaz:
https://doaj.org/article/cd5335aa8f1a4b33a4ff0cfc2e30a650
Publikováno v:
Cancers
Volume 15
Issue 4
Pages: 1318
Volume 15
Issue 4
Pages: 1318
The abietane diterpenoids ferruginol (1), tanshinone IIA (3), and carnosol (4) are well-known for their interesting pharmacological properties, including antitumor, similar to other natural and semisynthetic abietanes. In this study, a pair of semisy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b491a66d5150a8e76e84bd37db50c814
Autor:
Miguel A, González-Cardenete, Damir, Hamulić, Francisco J, Miquel-Leal, Natalia, González-Zapata, Orlando J, Jimenez-Jarava, Yaneth M, Brand, Laura C, Restrepo-Mendez, Marlen, Martinez-Gutierrez, Liliana A, Betancur-Galvis, Maria L, Marín
Publikováno v:
Journal of Natural Products.
Viral infections affect several million patients annually. Although hundreds of viruses are known to be pathogenic, only a few can be treated in the clinic with available antiviral drugs. Naturally based pharmacotherapy may be a proper alternative fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32fa69e536eaa6073aba664ed838949
http://hdl.handle.net/10261/287514
http://hdl.handle.net/10261/287514